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Questions and Answers
What is the primary purpose of the housekeeper wave in the gastrointestinal tract?
What is the primary purpose of the housekeeper wave in the gastrointestinal tract?
Peristalsis is a voluntary movement of the gastrointestinal tract.
Peristalsis is a voluntary movement of the gastrointestinal tract.
False
Name one neurotransmitter involved in the peristalsis process.
Name one neurotransmitter involved in the peristalsis process.
Acetylcholine
The portion of the GIT that moves food from the proximal to the distal region is called the ______.
The portion of the GIT that moves food from the proximal to the distal region is called the ______.
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Match the following terms with their definitions:
Match the following terms with their definitions:
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Which nerve is associated with the sensory and motor functions of the mandible?
Which nerve is associated with the sensory and motor functions of the mandible?
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The GIT can store foodstuff in its current location.
The GIT can store foodstuff in its current location.
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What major activity is associated with gastrin?
What major activity is associated with gastrin?
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Somatostatin is released from the G cells located in the stomach.
Somatostatin is released from the G cells located in the stomach.
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Which stimuli trigger the release of gastrin?
Which stimuli trigger the release of gastrin?
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Somatostatin inhibits _______ and HCl release.
Somatostatin inhibits _______ and HCl release.
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Match the gastrointestinal hormone to its location:
Match the gastrointestinal hormone to its location:
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Where is somatostatin primarily secreted?
Where is somatostatin primarily secreted?
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What effect does somatostatin have on gastric secretions?
What effect does somatostatin have on gastric secretions?
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Amino acids can stimulate the release of gastrin.
Amino acids can stimulate the release of gastrin.
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Gastrin is primarily involved in the secretion of ____________ and pepsinogen.
Gastrin is primarily involved in the secretion of ____________ and pepsinogen.
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What hormone is primarily believed to mediate hunger in fasting states?
What hormone is primarily believed to mediate hunger in fasting states?
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Gastrin is released from the stomach in response to food and stimulates the secretion of gastric juice.
Gastrin is released from the stomach in response to food and stimulates the secretion of gastric juice.
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Name the phase characterized by the release of intestinal gastrin from intestinal cells.
Name the phase characterized by the release of intestinal gastrin from intestinal cells.
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The ___________ complex is triggered by motility and stimulates gastric juice secretion.
The ___________ complex is triggered by motility and stimulates gastric juice secretion.
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Which hormone is secreted during the postprandial state?
Which hormone is secreted during the postprandial state?
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The vagal stimulation primarily affects only the small intestine.
The vagal stimulation primarily affects only the small intestine.
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What triggers the release of most GI hormones after eating?
What triggers the release of most GI hormones after eating?
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__________ is released from the stomach and stimulates the gastric phase.
__________ is released from the stomach and stimulates the gastric phase.
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Match the following hormones to their respective roles:
Match the following hormones to their respective roles:
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Which phase involves reflex responses that stimulate gastric juice secretion?
Which phase involves reflex responses that stimulate gastric juice secretion?
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What is the main secretory product of Chief cells in the gastric gland?
What is the main secretory product of Chief cells in the gastric gland?
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Parietal cells secrete HCl and intrinsic factor.
Parietal cells secrete HCl and intrinsic factor.
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What is the secretory product of G cells?
What is the secretory product of G cells?
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The surface mucous cells secrete mucin in an __________ fluid.
The surface mucous cells secrete mucin in an __________ fluid.
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Match the gastric gland cells with their secretory products:
Match the gastric gland cells with their secretory products:
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Which cells are responsible for secreting intrinsic factor?
Which cells are responsible for secreting intrinsic factor?
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Acetylcholine is a secretory product of Chief cells.
Acetylcholine is a secretory product of Chief cells.
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What is the role of secretin in the digestive system?
What is the role of secretin in the digestive system?
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The secretion of __________ stimulates the intestinal secretion of water and electrolytes.
The secretion of __________ stimulates the intestinal secretion of water and electrolytes.
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What is the primary secretion of mucous neck cells?
What is the primary secretion of mucous neck cells?
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Tonic contractions are characterized by sustained amounts of calcium, leading to continuous contractions even in the absence of external stimuli.
Tonic contractions are characterized by sustained amounts of calcium, leading to continuous contractions even in the absence of external stimuli.
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What is the primary function of tonic contractions in sphincters?
What is the primary function of tonic contractions in sphincters?
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Which of the following is NOT a characteristic of phasic contractions?
Which of the following is NOT a characteristic of phasic contractions?
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Phasic contractions are responsible for the ______ movements that propel food through the digestive tract.
Phasic contractions are responsible for the ______ movements that propel food through the digestive tract.
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Match the following terms with their corresponding descriptions:
Match the following terms with their corresponding descriptions:
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Which of the following arteries is NOT involved in the arterial supply of the gastrointestinal tract?
Which of the following arteries is NOT involved in the arterial supply of the gastrointestinal tract?
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What is the primary purpose of the celiac artery in the GI tract?
What is the primary purpose of the celiac artery in the GI tract?
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The hepatic arteries exclusively supply blood to the liver.
The hepatic arteries exclusively supply blood to the liver.
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The arterial supply of the gastrointestinal tract is essential for providing ______ and ______ to the digestive organs.
The arterial supply of the gastrointestinal tract is essential for providing ______ and ______ to the digestive organs.
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Which of the following is NOT a potential result of this deficiency?
Which of the following is NOT a potential result of this deficiency?
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Gastrulation of the gastrointestinal tract occurs between the 3rd and 32nd weeks of gestation.
Gastrulation of the gastrointestinal tract occurs between the 3rd and 32nd weeks of gestation.
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What is a condition where a portion of the gastrointestinal tract is closed or absent?
What is a condition where a portion of the gastrointestinal tract is closed or absent?
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Meconium Ileus occurs when the first stool blocks the last part of the baby's ______.
Meconium Ileus occurs when the first stool blocks the last part of the baby's ______.
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Match the following embryological defects with their descriptions:
Match the following embryological defects with their descriptions:
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Which germ layer of the gastrointestinal tract is responsible for muscle and connective tissue development?
Which germ layer of the gastrointestinal tract is responsible for muscle and connective tissue development?
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Hypertrophy/Pyloric Stenosis involves the failure of the tract to develop.
Hypertrophy/Pyloric Stenosis involves the failure of the tract to develop.
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What characterizes radiating pain?
What characterizes radiating pain?
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Referred pain presents as somatic pain confined to a well-defined location.
Referred pain presents as somatic pain confined to a well-defined location.
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What is the primary difference between referred pain and radiating pain?
What is the primary difference between referred pain and radiating pain?
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Pain that initially is confined to a small area but then spreads is called __________ pain.
Pain that initially is confined to a small area but then spreads is called __________ pain.
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Match the following types of pain with their descriptions:
Match the following types of pain with their descriptions:
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Which of the following is a characteristic of tonic contractions?
Which of the following is a characteristic of tonic contractions?
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Phasic contractions are observed in smooth muscles and sphincters.
Phasic contractions are observed in smooth muscles and sphincters.
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_________ contractions are rhythmic contractions that occur at intrinsic frequencies and are typically short-lived.
_________ contractions are rhythmic contractions that occur at intrinsic frequencies and are typically short-lived.
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Match the following types of contractions with their descriptions:
Match the following types of contractions with their descriptions:
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What type of contractions are responsible for the peristaltic movements that propel food through the digestive tract?
What type of contractions are responsible for the peristaltic movements that propel food through the digestive tract?
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The celiac artery is involved in the arterial supply of the gastrointestinal tract.
The celiac artery is involved in the arterial supply of the gastrointestinal tract.
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The arterial supply of the gastrointestinal tract provides ______ and ______ to the digestive organs.
The arterial supply of the gastrointestinal tract provides ______ and ______ to the digestive organs.
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What is the duration of Phase 3 of the Myoelectric Complex?
What is the duration of Phase 3 of the Myoelectric Complex?
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Phase 2 of the Myoelectric Complex involves only quiescent periods with no contractions.
Phase 2 of the Myoelectric Complex involves only quiescent periods with no contractions.
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Name the muscle that primarily elevates the mandible.
Name the muscle that primarily elevates the mandible.
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Phase 1 is characterized by a quiescent period with __________ contractions.
Phase 1 is characterized by a quiescent period with __________ contractions.
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Match the phases of the Myoelectric Complex with their characteristics:
Match the phases of the Myoelectric Complex with their characteristics:
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Which division of the Trigeminal nerve is primarily involved in closing the mouth?
Which division of the Trigeminal nerve is primarily involved in closing the mouth?
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The Angle and surface of the ramus of the mandible are involved in elevating bone during Phase 3.
The Angle and surface of the ramus of the mandible are involved in elevating bone during Phase 3.
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What muscle action occurs in Phase 2 of the Myoelectric Complex?
What muscle action occurs in Phase 2 of the Myoelectric Complex?
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The __________ muscle is primarily responsible for retracting the mandible during the Myoelectric Complex.
The __________ muscle is primarily responsible for retracting the mandible during the Myoelectric Complex.
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Which muscle is described by the terms 'medial pterygoid' and 'elevates and retracts mandible'?
Which muscle is described by the terms 'medial pterygoid' and 'elevates and retracts mandible'?
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What is the main function of the fundic area of the stomach?
What is the main function of the fundic area of the stomach?
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The fundic area can accommodate a large portion of food without increasing pressure.
The fundic area can accommodate a large portion of food without increasing pressure.
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What type of movement may occur in the stomach when the fundus is filled with food?
What type of movement may occur in the stomach when the fundus is filled with food?
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The _______ layer is an additional muscle layer unique to the stomach.
The _______ layer is an additional muscle layer unique to the stomach.
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Match the following terms with their corresponding functions in the stomach:
Match the following terms with their corresponding functions in the stomach:
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Which process is primarily responsible for mixing food in the stomach?
Which process is primarily responsible for mixing food in the stomach?
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The stomach is the only organ that contains an oblique muscle layer.
The stomach is the only organ that contains an oblique muscle layer.
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What is the role of the lower esophageal sphincter?
What is the role of the lower esophageal sphincter?
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The structures involved in swallowing include the _______ and esophagus.
The structures involved in swallowing include the _______ and esophagus.
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Match the stomach regions with their primary functions:
Match the stomach regions with their primary functions:
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Study Notes
Regulation of Energy Homeostasis
- Systems of food intake regulation prevent overeating during meals.
- Long-term regulation maintains energy stores (fat) by regulating food intake and energy balance via insulin and leptin.
- Short-term regulation prevents overeating during each meal and involves signaling from the gastrointestinal tract (GIT) and the liver.
Hunger and Appetite Hormones
- Ghrelin and Leptin signal the hypothalamus to regulate appetite.
- Ghrelin increases appetite, produced in the stomach.
- Leptin decreases appetite, produced in adipose tissue.
- Ghrelin levels rise when the stomach is empty, stimulating appetite, and fall when full.
- Ghrelin is a 28-amino-acid peptide hormone, first described in 1999.
- It stimulates the pituitary gland to release growth hormone.
- Ghrelin is produced by endocrine cells lining the stomach and proximal small intestine, including P/D1 cells in the stomach fundus.
- Ghrelin is associated with psychiatric conditions such as anorexia nervosa.
- Leptin is a protein hormone made by adipocytes.
- It sends signals to the hypothalamus to indicate satiety and boosts metabolism.
- Leptin levels rise with increased adipose tissue size and communicate energy storage status.
- Leptin levels show circadian fluctuations and change with nutritional intake.
Gastrointestinal Tract (GIT)
- Embryological development involves three germinal layers: Mesoderm, Ectoderm, and Endoderm.
- Embryological defects include atresia (closed or absent orifices), hypertrophy/pyloric stenosis (thickening/narrowing of the pylorus), omphalocele (abdominal contents outside the abdominal cavity), esophageal atresia, duodenal atresia, and jejunal and ileal atresia.
- Functional anatomy includes the mouth, esophagus, stomach, small intestine, large intestine and accessory organs (liver, pancreas, gallbladder).
- Control mechanisms involve the nervous system (autonomic and enteric) and the endocrine system (hormones).
- Accessory organs secrete substances for digestion and nutrient absorption.
GIT Motility
- Types of movements include peristalsis (propelling food), segmentation (mixing food), haustral contractions (mixing in large intestine), and mass movements (large intestine propulsion).
- Tonic contractions are sustained, while phasic contractions are rhythmic and temporary.
- Sphincters (gastroesophageal, pyloric, ileocecal, internal anal) regulate GIT area division.
- Myenteric (Auerbach's) and submucosal (Meissner's) plexuses control GIT motility and secretions.
- Migrating myoelectric complex (MMC) moves undigested materials during interdigestive periods.
Stomach
- The stomach stores and churns food, mixes it and refines the food into chyme, before allowing it to the small intestines
- The stomach has three layers of muscles (circular, longitudinal, and oblique).
- Oblique muscles are unique to the stomach for churning and mixing.
Intestines
- Small intestine: Completes digestion, absorbs nutrients and water, and has villi to increase surface area.
- Large intestine: Reabsorbs water and ions, forms and stores feces.
- Small and large intestines have different specialized layers for absorption and propulsion.
- The intestinal layers include mucosa, submucosa, muscularis externa, and serosa.
- Cells in the intestinal lining (enterocytes, goblet cells, enteroendocrine cells, Paneth cells).
Control of Defecation
- Intrinsic defecation reflex: Feces stimulate stretch receptors in the rectum triggers the relaxation of the internal anal sphincter.
- Integrated defecation reflex involves parasympathetic stimulation.
- Conscious control involves the external anal sphincter.
Secretion in GIT
- Salivary glands produce saliva to moisten and lubricate food.
- Salivary glands produce amylase for starch digestion.
- Gastric glands secrete HCl, pepsinogen (precursor of pepsin), intrinsic factor, and mucus.
- Intestinal glands secrete various enzymes (e.g. peptidases, sucrase, lactase, maltase) and bicarbonate to aid digestion and absorption.
- Different glands have different secretion types and consistencies.
- Salivary glands produce different types of saliva with varying viscosity and mineral content.
Bristol Stool Chart
- A tool for describing stool consistency (types 1-7) for assessment of bowel health.
- Viscous and solid stools are associated with constipation, while liquid stools with diarrhea.
Nervous System Control
- Autonomic nervous system(ANS): Sympathetic inhibits most GIT functions and parasympathetic stimulates most.
- Enteric nervous system (ENS) is the intrinsic control mechanism in the tract.
- CNS (central nervous system) control of reflexes (e.g. defecation).
Additional information
- Hormones (e.g., gastrin, secretin, GIP) regulate digestive secretions and motility.
- GI tract histology details its layers (mucosa, submucosa, muscularis externa, serosa/adventitia) and specialized cells.
- Autonomic and enteric nervous systems coordinate digestive functions.
- Food types (fatty, etc.) affect release of hormones and contractions.
- Stomach, intestines, and accessory organs have different secretions to complete digestion.
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Description
Test your knowledge on the functions and hormones of the gastrointestinal tract. This quiz covers key concepts including peristalsis, the role of gastrin, and the effects of somatostatin. Perfect for students studying gastrointestinal physiology or related fields.