Gastrointestinal System - Advanced
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Questions and Answers

Why are the enzymes Pepsin and Trypsin initially secreted as Pepsinogen and Trypsinogen (proenzymes)?

  • The proenzymes break down different proteins from the enzymes.
  • They are secreted when the GI tract is empty and only activated when food is present.
  • Proenzymes act as hormones in the digestive tract.
  • To prevent self-digestion of secreting organs. (correct)
  • What are the main sources of bicarbonate in the intestine?

  • Bile and pancreatic juice. (correct)
  • Stomach acid and saliva.
  • Secretions of the intestinal epithelium.
  • Digested food.
  • What is the main role of bicarbonate in the small intestine?

  • Maintain optimal pH for enzymatic digestion. (correct)
  • Regulate water content of the intestinal contents.
  • Remove CO2 from the digestive system.
  • Break down proteins into amino acids.
  • Which part of the stomach is primarily responsible for the secretion of stomach juices?

    <p>Fundus</p> Signup and view all the answers

    What is the main effect of motilin on the digestive tract?

    <p>Increased gastric motor activity</p> Signup and view all the answers

    Which of the following two hormones have OPPOSITE effects on gastric acid secretion?

    <p>Somatostatin and CCK</p> Signup and view all the answers

    Which phase of gastric secretion does not require the presence of food in the stomach?

    <p>Cephalic phase</p> Signup and view all the answers

    Which of the following can be absorbed in the stomach?

    <p>There is no absorption of nutrients in the stomach</p> Signup and view all the answers

    Which of the following is NOT a role of motility in the gastrointestinal system?

    <p>Digestion</p> Signup and view all the answers

    Bile is released into the duodenum by which organ?

    <p>Gall bladder</p> Signup and view all the answers

    What type of food is primarily digested in the stomach?

    <p>Protein</p> Signup and view all the answers

    The main process relating to digestion which occurs in the large intestine is:

    <p>Fermentation</p> Signup and view all the answers

    Fat is mainly absorbed by the:

    <p>Lymphatic system</p> Signup and view all the answers

    Secretions of the exocrine pancreas play a role in the digestions of:

    <p>Proteins, carbohydrates, lipids and nucleic acids</p> Signup and view all the answers

    Which branch of the nervous system regulates the function of the gastrointestinal system?

    <p>Autonomic</p> Signup and view all the answers

    Ageing of the gastrointestinal system is frequently characterised by an increased incidence of constipation. This may be caused by:

    <p>Slow peristalsis</p> Signup and view all the answers

    Which of the following is NOT a function of the liver?

    <p>Regulation of gastrointestinal motility</p> Signup and view all the answers

    What are the roles of water in digestion?

    <p>Hydrolysis; lubrication and dilution</p> Signup and view all the answers

    Why does eating a large meal make one sleepy?

    <p>Effect of cholecystokinin (CCK) on the brain</p> Signup and view all the answers

    Pancreatitis, which causes reduced production and secretion of pancreatic enzymes, will have the following symptoms:

    <p>Decreased digestion and absorption of nutrients and diarrhoea</p> Signup and view all the answers

    Study Notes

    Gastrointestinal System - Advanced

    • Enzyme Secretion: Pepsin and Trypsin are initially secreted as inactive proenzymes (Pepsinogen and Trypsinogen) to prevent self-digestion of the secreting organs. These enzymes are activated only when food is present.

    • Bicarbonate Sources: Bicarbonate in the intestines primarily comes from bile and pancreatic juice, and secretions of the intestinal epithelium.

    • Bicarbonate Role: Bicarbonate in the small intestine helps maintain the optimal pH for enzymatic digestion.

    • Stomach Secretion: The stomach's fundus, pyloric antrum, and cardia secrete stomach juices.

    • Motilin's Effect: Motilin plays a role in the digestive tract by impacting movement through the system.

    • Fat Absorption: Fat is primarily absorbed by the lymphatic system.

    • Digestion Mechanisms: Fermentation is the main process in the large intestine.

    • Stomach Digestion: Proteins are the primary food type digested in the stomach.

    • Gastric Phase: The gastric phase of gastric secretion requires food to be present in the stomach.

    • Liver Function: The liver's roles include destroying old red blood cells, forming blood plasma proteins, and storing glucose but does not regulate gastrointestinal motility.

    • Nervous System Regulation: The autonomic branch of the nervous system regulates the gastrointestinal system.

    • Pancreatic Secretion Issues: Reduced pancreatic enzyme production leads to decreased digestion of nutrients and diarrhea.

    • Digestion Substances: The gastrointestinal system digests proteins, carbohydrates, lipids, and nucleic acids.

    • Motility Roles: Motility in the gastrointestinal system plays roles in exposure, mixing, and movement along the digestive tract.

    • Bile Release: Bile is released into the duodenum through the gall bladder.

    • Sleepy after a Large Meal: Eating a large meal may lead to sleepiness due to cholecystokinin (CCK) effects on the brain.

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    Description

    Test your knowledge on the advanced concepts of the gastrointestinal system, including enzyme secretion, bicarbonate sources and roles, and digestion mechanisms. This quiz covers key functions of various organs involved in digestion and the biochemical processes that occur in the digestive tract.

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