30 Questions
What is the primary mechanism by which H. pylori bacteria attach to the epithelial cells of the stomach and duodenum?
Through adherence to the epithelial cells
What is the purpose of Bismuth in H. pylori treatment?
To disrupt the bacterial cell wall
What is the primary advantage of using Metronidazole in H. pylori treatment?
It is often used due to bacterial resistance to Amoxicillin and Tetracycline
What is the effectiveness of Triple Therapy in treating H. pylori infections?
80-85%
What is the primary mechanism of action of Clarithromycin in H. pylori treatment?
Inhibiting protein synthesis
What is the primary mode of transmission of H. pylori infections?
Direct contact with saliva, vomit, or stool
What is the purpose of the Proton pump inhibitor in H. pylori treatment?
To reduce acid production and create an environment conducive to antibiotic activity
What percentage of Peptic Ulcer Disease (PUD) is caused by H. pylori?
80-85%
What is the primary disadvantage of using Pylori repeatedly or for more than 2 months at a time?
It can cause black stools and constipation
What is the advantage of Quadruple Therapy over Triple Therapy in treating H. pylori infections?
It is as efficacious as Triple Therapy but with a shorter treatment duration
What is the name of the condition that is linked to cancer of the esophagus and is characterized by the need for monitoring?
Barrett's Esophagus
What is the primary function of gastric rugae?
To increase the surface area for nutrient absorption
What is the primary mechanism of action of H2 receptor blockers?
Competitive inhibition of histamine H2 receptors
Which type of cells are responsible for the production of mucus in the stomach lining?
Mucous cells
What is the role of histamine in the production of gastric acid?
It aids in the release of histamine from ECL cells
Which of the following antacids is contraindicated in patients with impaired renal function?
Aluminum hydroxide + magnesium hydroxide
What is the minimum antacid neutralizing capacity (ANC) required by the FDA per dose?
5 meq
Where are G-cells primarily located in the stomach?
Pyloric antrum
What is the function of delta (D) cells in the gastrointestinal tract?
To inhibit the production of acid in the stomach
Which of the following proton pump inhibitors was removed from the market by the FDA due to concerns about its potential to cause cancer?
Ranitidine
What is the mechanism of action of misoprostol?
Stimulating prostaglandin E1 receptors on parietal cells
What is the primary function of enterochromaffin (EC) cells in the stomach?
To release serotonin
What is the primary indication for the use of pirenzepine?
Adjunct therapy for NSAID-induced injury
What is the purpose of the gastric mucosal barrier in the stomach?
To protect the epithelium from harsh acid conditions
What is the primary symptom of gastroesophageal reflux disease (GERD)?
Heartburn
What is the mechanism of action of sucralfate?
Forming a protective barrier on the ulcer site
Which of the following is a common side effect of misoprostol?
Diarrhea
What is a potential complication of GERD?
Esophageal ulcer
What is the primary mechanism of action of proton pump inhibitors?
Inhibiting the production of gastric acid through the irreversible inhibition of proton pumps
What is the abnormal epithelium that replaces the normal esophageal lining in some patients with GERD?
Barrett's epithelium
Test your knowledge of the stomach's structure and function, including the gastric rugae, stomach lining, gastric glands, and mucous cells. Learn about the role of mechanoreceptors in stomach expansion and nutrient absorption during digestion.
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