Gastrointestinal Disorders Quiz
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Questions and Answers

Which of the following does NOT predispose to Gastric Carcinoma?

  • Pyloric Stenosis (correct)
  • Infection with H. Pylori
  • Smoked & Salted Foods
  • Hypochlorhydria
  • Cigarette Smoking

    • Which of the following is NOT seen in Celiac Disease?

  • Loss of Microvillous Brush Border
  • Atrophy of Villi
  • Infiltration of Lamina Propria by Plasma Cells and Lymphocytes
  • Elongated Crypts
  • Epitheloid Granuloma (correct)

    • Which of the following is NOT a known complication of Duodenal Ulcers?

  • Malignant Transformation
  • Bleeding
  • Pyloric Stenosis (correct)
  • Perforation
  • Obstruction

    • Squamous Carcinoma of the Oesophagus is associated with the following EXCEPT:

    <p>H. Pylori Infection</p> Signup and view all the answers

    The following are associated with Mallory-Weiss Syndrome (oesophageal laceration) EXCEPT:

    <p>Squamous Carcinoma</p> Signup and view all the answers

    The following are features of Autoimmune Gastritis EXCEPT:

    <p>Hyperacidity</p> Signup and view all the answers

    Which of the following is NOT associated with Barrett's Oesophagus:

    <p>Keratinizing Squamous Carcinoma</p> Signup and view all the answers

    Which of the following is NOT associated with Acute Gastritis:

    <p>Crohn's Disease</p> Signup and view all the answers

    The following are risk factors for Colo-Rectal Cancer EXCEPT:

    <p>Intestinal Amoebiasis</p> Signup and view all the answers

    Which of the following is NOT a feature of Appendiceal Carcinoids:

    <p>Always cause Carcinoid Syndrome</p> Signup and view all the answers

    The following are features of Ulcerative Colitis EXCEPT:

    <p>Well Defined Epitheloid Granuloma</p> Signup and view all the answers

    The following are features of Crohn's Disease EXСЕРТ:

    <p>Megacolon</p> Signup and view all the answers

    Which of the following is NOT true about Diverticular Disease (colonic diverticulosis):

    <p>Infiltration of Lamina Propria by Mononuclear Inflammatory Cells</p> Signup and view all the answers

    Which of the following is NOT true about Retroperitoneal Fibrosis:

    <p>Develops into well differentiated Fibrosarcoma</p> Signup and view all the answers

    Which of the following is NOT an Extraintestinal manifestation of Crohn's Disease:

    <p>Cholecystitis</p> Signup and view all the answers

    Which of the following is NOT a necessary component of Cirrhosis of the Liver:

    <p>Fibrosis</p> Signup and view all the answers

    Crohn's Disease (regional enteritis) is associated with each of the following Extraintestinal manifestations EXCEPT:

    <p>Rheumatic Carditis</p> Signup and view all the answers

    Which of the following diseases is likely to be complicated by Malignancy:

    <p>Familial Polyposis Coli</p> Signup and view all the answers

    Which of the following Uterine Lesions has a greatest potential to evolve into carcinoma:

    <p>Complex Hyperplasia with Atypia</p> Signup and view all the answers

    All of the following GI diseases have been shown to be associated with an increased incidence of Malignancy EXCEPT:

    <p>Whipple's Disease</p> Signup and view all the answers

    In Chronic Idiopathic Ulcerative Colitis, which of the following is/are usually found:

    <p>Both A &amp; B</p> Signup and view all the answers

    Which of the following is MOST characteristic of Crohn's Disease as compared with Ulcerative Colitis:

    <p>Involves the Colon Wall Transmurally</p> Signup and view all the answers

    Which of the following is the commonest cause of Subarachnoid Hemorrhage:

    <p>Rupture of Berry Aneurysm</p> Signup and view all the answers

    Increased Maximal Gastric Acid Output is seen in:

    <p>Zollinger-Ellison Syndrome</p> Signup and view all the answers

    Which of the following is least likely to be complicated by Colorectal Carcinoma:

    <p>Hyperplastic Polyps</p> Signup and view all the answers

    Which of the following is NOT associated with Sjorgen's Syndrome:

    <p>Can develop into Epithelial Carcinoma</p> Signup and view all the answers

    Which of the following is associated with Salivary Gland Calculi:

    <p>Suppurative Parotitis</p> Signup and view all the answers

    The following are true about Pleomorphic Salivary Gland Adenoma EXCEPT:

    <p>Commonly (more than 50%) become Malignant</p> Signup and view all the answers

    Which of the following is NOT true about Plummer-Vinson Syndrome:

    <p>Increased Incidence of Carcinoma</p> Signup and view all the answers

    Barrett's Esophagus is:

    <p>Metaplasia of Oesophageal Squamous Epithelium</p> Signup and view all the answers

    Which of the following is true about Hypertrophic Pyloric Stenosis:

    <p>The Pyloric Muscle is greatly thickened</p> Signup and view all the answers

    Which of the following is NOT a Gastric Mucosa Protection mechanism:

    <p>Bacterial Flora</p> Signup and view all the answers

    Which of the following is true about Ulcerative Colitis:

    <p>Crypt Abscesses are frequently seen</p> Signup and view all the answers

    Estimation of which of the following is used for the diagnosis of Carcinoid Syndrome:

    <p>Urinary 5HIAA</p> Signup and view all the answers

    Which of the following is true about Crohn's Disease:

    <p>Inflammation is Transmural</p> Signup and view all the answers

    Gastric Lymphoma is a known complication of:

    <p>H. Pylori associated Gastritis</p> Signup and view all the answers

    The following are features of Crohn's Disease EXCEPT:

    <p>High Incidence of Malignancy</p> Signup and view all the answers

    Which of the following bears the highest risk of Malignant Complication:

    <p>Familial Polyposis Coli</p> Signup and view all the answers

    String Sign in Radiology is seen in:

    <p>Crohn's Disease</p> Signup and view all the answers

    Non-Caseating Granulomas are seen in all of the following EXСЕРТ:

    <p>Ulcerative Colitis</p> Signup and view all the answers

    Which of the following Malignant Tumors is most likely to be found in the Jejunum:

    <p>Adenocarcinoma</p> Signup and view all the answers

    Which of the following most likely arise as a complication of Gastric Adenocarcinoma:

    <p>Krukenberg Tumor</p> Signup and view all the answers

    Which of the following Bone Lesions is associated with Café-au-Lait Skin Pigmentation and Endocrinopathy:

    <p>Polystitic Fibrous Dysplasia</p> Signup and view all the answers

    Which of the following is associated with Ulcerative Colitis:

    <p>Primary Biliary Cirrhosis</p> Signup and view all the answers

    Estimation of level CEA (Carcino-Embryonic Antigen) is most helpful in:

    <p>Post-Surgical Follow-up of Colo-Rectal Cancer</p> Signup and view all the answers

    Cobble-Stone appearance is seen in:

    <p>Crohn's Disease</p> Signup and view all the answers

    Crypt Abscesses, Pseudopolyps and Broad-Based Ulcer are seen in:

    <p>Ulcerative Colitis</p> Signup and view all the answers

    Which of the following Cardiac Lesions is most likely to develop in a patient who has advanced Carcinoma of the Pancreas:

    <p>Non-Bacterial Thrombotic Endocarditis</p> Signup and view all the answers

    Which of the following has the highest risk for Colo-Rectal Carcinoma:

    <p>Familial Polyposis Coli</p> Signup and view all the answers

    Which of the following is NOT strongly associated with Smoking:

    <p>Renal Cell Carcinoma</p> Signup and view all the answers

    Which of the following is likely to be associated with a Flattened Gastric Mucosa with No Acute Ulceration:

    <p>Autoantibodies to Parietal Cells</p> Signup and view all the answers

    Crypt Abscesses, Fissures, Serpentine Ulcer & Granulomas are seen in:

    <p>Crohn's Disease</p> Signup and view all the answers

    Which of the following Large Intestinal Polyps carries the highest risk for cancer:

    <p>Sessile Villous Adenoma larger than 4cm in Diameter</p> Signup and view all the answers

    The following is NOT TRUE about Crohn's Disease:

    <p>The disease is limited to the Terminal Ileum</p> Signup and view all the answers

    Which of the following morpholgic features are NOT SEEN in Ulcerative Colitis:

    <p>Non-Caseating Granulomas</p> Signup and view all the answers

    Pseudomyxoma Peritonei is most closely associated with:

    <p>Mucinous Cystadenoma</p> Signup and view all the answers

    Steatorrhea is NOT associated with:

    <p>Obstructive Jaundice</p> Signup and view all the answers

    Which of the following is associated with Carcinoma of the Head of the Pancreas:

    <p>Non-Bacterial Thrombotic Endocarditis</p> Signup and view all the answers

    The following are features of an Acute Gastric Ulcer EXCEPT:

    <p>Heals with Fibrosis</p> Signup and view all the answers

    The most significant criteria for the histological diagnosis of Barrett's Esopgahus:

    <p>All of the Above</p> Signup and view all the answers

    The Histiological Components of Pleomorphic Salivary Gland Adenoma are:

    <p>All of the Above</p> Signup and view all the answers

    White Plaques in the Oral Cavity of 3 days duration in a Child 8 months old are most likely:

    <p>Oral Candidiasis</p> Signup and view all the answers

    Gastric Signet Cell Carcinoma metastasizing to both ovaries is:

    <p>Krukenberg Tumor</p> Signup and view all the answers

    Study Notes

    Gastric Carcinoma Risk Factors (Question 610)

    • H. Pylori infection is a risk factor
    • Cigarette smoking is a risk factor
    • Hypochlorhydria is a risk factor
    • Pyloric Stenosis is NOT a risk factor
    • Smoked and salted foods are risk factors

    Celiac Disease Features (Question 611)

    • Atrophy of villi is a feature
    • Epitheloid granulomas are NOT a feature
    • Loss of microvilli brush border is a feature
    • Elongated crypts are a feature
    • Infiltration of lamina propria by plasma cells and lymphocytes is a feature

    Duodenal Ulcer Complications (Question 614)

    • Bleeding is a complication
    • Malignant transformation is a complication
    • Perforation is a complication
    • Obstruction is a complication
    • Pyloric stenosis is NOT a complication

    Squamous Carcinoma of the Oesophagus (Question 617)

    • High incidence in blacks is NOT a factor associated

    Mallory-Weiss Syndrome (Question 626)

    • Severe retching is associated
    • Alcoholism is associated
    • Excessive vomiting is associated
    • Haematemesis is associated
    • Squamous carcinoma is NOT associated

    Autoimmune Gastritis Features (Question 628)

    • Autoantibodies to gastric parietal cells are a feature
    • Association with Hashimoto's thyroiditis is a feature
    • Gastric mucosal atrophy is a feature
    • Hyperacidity is NOT a feature
    • Intestinal metaplasia is a feature

    Barrett's Oesophagus Associations (Question 629)

    • Gastrointestinal bleeding is associated
    • Reflux oesophagitis is associated
    • Keratinizing squamous carcinoma is associated
    • Long history of heartburn is associated
    • Epithelial dysplasia is associated

    Acute Gastritis Associations (Question 630)

    • Severe stress is associated
    • Shock is associated
    • Excessive alcohol consumption is associated
    • Crohn's disease is NOT associated
    • Excessive aspirin use is associated

    Colorectal Cancer Risk Factors (Question 636)

    • Low-fiber diet is a risk factor
    • Familial polyposis coli is a risk factor
    • Intestinal amoebiasis is NOT a risk factor

    High Cholesterol Intake and Obesity in Various Systems (Question 639 and 640)

    • High cholesterol intake and obesity can affect various parts of the body, potentially including the gastrointestinal tract (GIT), breasts, and gonads among others. (Note: Questions 639 and 640 lack enough detail.)

    Diverticular Disease (Question 644)

    • Most common site is the sigmoid colon
    • Risk factor for carcinoma
    • Occurs alongside taeniae coli
    • Focal weakness in the colonic wall

    Retroperitoneal Fibrosis (Question 645)

    • Causes ureteric obliteration
    • Encircles the abdominal aorta
    • Shows prominent lymphocyte infiltrate
    • Reported following Methysergide administration along with other medication
    • Can progress to well-differentiated fibrosarcoma

    Crohn's Disease Extraintestinal Manifestations (Question 646)

    • Polyarthritis is a manifestation
    • Ankylosing spondylitis is a manifestation
    • Cholecystitis is NOT a manifestation
    • Erythema nodosum is a manifestation
    • Uveitis is a manifestation

    Cirrhosis of the Liver Components (Question 650)

    • Fibrosis is a component
    • Nodules of regenerating liver cells are a component
    • Active (acute) inflammatory process with piecemeal necrosis is a component
    • Distortion of entire liver architecture is a component
    • Distortion of intrahepatic blood flow is a component

    Crohn's Disease Extraintestinal Manifestations (Question 651)

    • Pernicious anemia is NOT an extraintestinal manifestation
    • Uveitis is an extraintestinal manifestation
    • Ankylosing spondylitis is an extraintestinal manifestation
    • Rheumatic carditis is an extraintestinal manifestation
    • Erythema nodosum is an extraintestinal manifestation

    Diseases Complicated by Malignancy (Question 654)

    • Familial polyposis coli is likely to be complicated by malignancy
    • Crohn's disease is likely
    • Ulcerative colitis is not as high of a risk
    • Chronic duodenal ulcers are likely
    • H. pylori gastritis is not as high of a risk

    Uterine Lesions Risk of Carcinoma (Question 655)

    • Complex hyperplasia with atypia has greatest potential for evolving into carcinoma

    GI Diseases and Increased Malignancy (Question 657)

    • Achalasia
    • Celiac sprue
    • Whipple's disease
    • Ulcerative colitis are not linked to Increased Malignancy Risk
    • Crohn's disease (regional enteritis) IS associated with increased malignancy

    Chronic Idiopathic Ulcerative Colitis (Question 658)

    • Fistula-in-ano is a feature
    • Linear serpiginous ulcers are a feature
    • Both fistula-in-ano and linear serpiginous ulcers (option c) are features
    • Neither fistula-in-ano nor linear serpiginous ulcers (option d) are not features

    Crohn's Disease vs. Ulcerative Colitis (Question 659)

    • Crohn's tends to occur in younger adults
    • Crohn's tends to involve the mucosa continuously
    • Crohn's involves the colon wall transmurally
    • Crohn's can occur in both large and small intestines
    • Crohn's increases the probability of developing cancer

    Subarachnoid Hemorrhage Causes (Question 660)

    • Rupture of berry aneurysm is the most common cause
    • Rupture of vascular malformation is a cause
    • Blood dyscrasia are associated with bleeding
    • Polyarteritis nodosa are associated with bleeding
    • Tertiary syphilis are associated with bleeding

    Increased Maximal Gastric Acid Output (Question 661)

    • Pernicious anemia is associated
    • Gastric carcinoma is associated
    • Zollinger-Ellison syndrome is associated
    • Aging is not associated

    Diseases Least Likely to be Complicated by Colorectal Carcinoma (Question 666)

    • Familial Adenomatous Polyposis Coli
    • Villous Adenoma
    • Tubular Adenoma
    • Hyperplastic polyps
    • Ulcerative colitis is less likely

    Sjogren's Syndrome Associations (Question 669)

    • Autoimmune aetiology
    • Affects salivary and lacrimal glands
    • Associated with hypergammaglobulinemia
    • Can develop into epithelial carcinoma
    • Associated with rheumatoid arthritis

    Salivary Gland Calculi Associations (Question 670)

    • Sjogren's syndrome
    • Mumps
    • Salivary gland carcinoma
    • Suppurative parotitis
    • Adenoid cystic carcinoma

    Pleomorphic Salivary Gland Adenoma (Question 671))

    • Arises most commonly in the parotid gland
    • Well-circumscribed, but can extend into adjacent tissues
    • Composed of epithelial and mesenchymal elements
    • Not commonly malignant (most commonly are benign)
    • Most common salivary gland tumour

    Plummer-Vinson Syndrome (Question 673)

    • Transverse folds of oesophagus mucosa
    • Associated with megaloblastic anaemia
    • More common in females
    • Increased incidence of carcinoma
    • Visualised by radiologist during barium swallow

    Barrett's Esophagus (Question 674)

    • Metaplasia of oesophageal squamous epithelium
    • Web of folded mucosa
    • Pulsion diverticulum
    • In situ carcinoma of oesophagus
    • Oesophageal candidiasis

    Hypertrophic Pyloric Stenosis (Question 675)

    • Commonly affects females
    • Usually presents at the age of 5 years
    • Obstruction due to hamartoma of mucosa
    • Pyloric muscle is greatly thickened
    • Predisposes to chronic peptic ulcer

    Gastric Mucosa Protection Mechanisms (Question 676)

    • Mucus secretion
    • Bicarbonate secretion
    • Epithelial barrier
    • Prostaglandins
    • Bacterial flora is NOT a protection mechanism

    Ulcerative Colitis (Question 685)

    • Inflammation is NOT transmural
    • Characterized by skip lesions
    • Affects all parts of the gastrointestinal tract
    • Crypt abscesses are frequently seen
    • Non-caseating granulomas are NOT seen

    Carcinoid Syndrome Diagnosis (Question 686)

    • Estimation of urinary 5HIAA is used for diagnosis
    • Urinary VMA and amino acids, serotonin, gastrin are not used

    Crohn's Disease (Question 687)

    • Inflammation is transmural
    • Affects small and large intestines
    • Commonly complicated by malignancy
    • Is not a cause of malabsorption
    • Is associated with extraintestinal lesions

    Gastric Lymphoma Complications (Question 688)

    • Zollinger-Ellison syndrome
    • Autoimmune gastritis
    • Gastric Crohn's disease
    • H. pylori associated gastritis
    • Peutz-Jegher syndrome

    Crohn's Disease Features (Question 689)

    • Skip lesions are a feature
    • Deep fissures are a feature
    • Granuloma formation is a feature
    • Fistula is a feature
    • High incidence of malignancy is a feature

    Highest Risk of Malignant Complication (Question 689)

    • Familial polyposis coli
    • Crohn's disease
    • Ulcerative colitis
    • Villous adenoma of the rectum
    • Celiac disease

    String Sign in Radiology (Question 690)

    • Carcinoma of the oesophagus
    • Achalasia
    • Hypertrophic pyloric stenosis
    • Crohn's disease
    • Hirschsprung's disease

    Non-Caseating Granulomas (Question 709)

    • Crohn's disease
    • Ulcerative colitis
    • Primary biliary cirrhosis
    • Temporal arteritis
    • Sarcoidosis

    Jejunum Malignant Tumors (Question 713)

    • Squamous cell carcinoma
    • Adenocarcinoma
    • Clear cell carcinoma
    • Lymphoma
    • Fibrosarcoma

    Gastric Adenocarcinoma Complications (Question 714)

    • Barrett mucosa
    • Cushing syndrome
    • Krukenberg tumor
    • Oesophageal varices
    • Primary sclerosing cholangitis

    Bone Lesions with Café-Au-Lait Spots (Question 715)

    • Osteomalacia
    • Osteopetrosis
    • Osteogenesis imperfecta
    • Polycystic fibrous dysplasia
    • Aneurysmal bone cyst

    Ulcerative Colitis Associations (Question 722)

    • Acute pancreatitis
    • Fistula formation
    • H. pylori associated gastritis
    • Primary sclerosing cholangitis
    • Primary biliary cirrhosis

    CEA Estimation (Question 730)

    • CEA (Carcino-embryonic antigen) level estimation in most helpful in assessing colorectal cancer

    Pre-invasive Colorectal Cancer Diagnosis (Question 730)

    • Diagnosis of pre-invasive colorectal cancer
    • Diagnosis of metastatic colorectal cancer
    • Post surgical follow-up of colorectal cancer
    • Malignant change in ulcerative colitis
    • Malignant change in Crohn's disease

    Cobblestone Appearance (Question 732)

    • Ulcerative colitis
    • Ischemic colitis
    • Crohn's disease
    • Non-familial polyposis
    • Diverticulitis

    Crypt Abscesses, Pseudopolyps (Question 737)

    • Intestinal schistosomiasis
    • Intestinal amoebiasis
    • Crohn's disease
    • Ulcerative colitis
    • Enteric fever

    Cardiac Lesions in Carcinoma of the Pancreas (Question 738)

    • Dilated cardiomyopathy
    • Non-bacterial thrombotic endocarditis
    • Acute fibrinous pericarditis
    • Endocardial fibrosis
    • Acute myocardial infarction

    Colorectal Carcinoma Risk (Question 741)

    • Ulcerative colitis
    • Crohn's disease
    • Familial polyposis coli
    • Non-familial polyposis
    • Diverticulosis

    Smoking Associations (Question 747)

    • Thromboangitis obliterans
    • Atherosclerosis
    • Type B chronic gastritis
    • Renal cell carcinoma
    • Impotence

    Flattened Gastric Mucosa (Question 754)

    • Diet high in nitrites
    • Hyperchlorohydria
    • Hypoparathyroidism
    • Menetrier disease
    • Autoantibodies to parietal cells

    Crypt Abscesses, Fissures (Question 758)

    • Intestinal schistosomiasis
    • Intestinal amoebiasis
    • Crohn's disease
    • Ulcerative colitis
    • Enteric fever

    Large Intestinal Polyps and Cancer Risk (Question 767)

    • Tubular adenoma smaller than 1 cm in diameter
    • Schistosomal inflammatory polyp
    • Hyperplastic polyp
    • Sessile villous adenoma larger than 4 cm in diameter
    • Juvenile polyp

    Crohn's Disease (Question 779)

    • Transmural involvement of bowel
    • Non-caseating granulomas
    • Formation of fistula
    • Cobblestone appearance of the mucosa
    • Limited to the terminal ileum

    Ulcerative Colitis Morphological Features (Question 787)

    • Non-caseating granulomas are NOT seen
    • Pseudopolyps are seen
    • Toxic megacolon is seen
    • Crypt abscesses are seen

    Lamina Propria Infiltration (Question 883)

    • Infiltration of the lamina propria by mononuclear inflammatory cells

    Pseudomyxoma Peritonei (Question 804)

    • Mucinous cystadenoma
    • Granulosa cell tumor
    • Endometroid carcinoma
    • Dysgerminoma
    • Hilus cell tumor

    Celiac Disease and Steatorrhea (Question 816)

    • Celiac disease, NOT associated with steatorrhea
    • Liver cirrhosis
    • Giardiasis
    • Obstructive jaundice
    • Chronic intestinal schistosomiasis

    Carcinoma of the Head of Pancreas (Question 832)

    • Dilated cardiomyopathy, associated with carcinoma of the head of the pancreas
    • Non-bacterial thrombotic endocarditis
    • Acute fibrinous pericarditis
    • Endocardial fibrosis
    • Acute myocardial infarction

    Acute Gastric Ulcer Features (Question 880)

    • Found anywhere in the stomach
    • Usually multiple
    • Usually small (less than 1 cm)
    • Adjacent mucosas are not remarkable
    • Heals with fibrosis

    Barrett's Esophagus Histologic Criteria (Question 883)

    • Presence of lamina propria papillae in the upper ⅓ of epithelium
    • Neutrophil inflammatory infiltrate
    • Presence of goblet cells
    • Hyperkeratosis and acanthosis of squamous epithelium

    Pleomorphic Salivary Gland Adenoma Histology (Question 884)

    • Glandular structures
    • Solid nests of epithelial cells
    • Foci of cartilaginous metaplasia
    • Myxomatous stroma

    Oral Cavity White Plaques in Children (Question 885)

    • Snail track ulcer
    • Mucosal leishmaniasis
    • Burkitt's lymphoma
    • Oral candidiasis
    • Bullous pemphigoid

    Gastric Signet Cell Carcinoma Metastasis (Question 898)

    • Pseudomyxoma peritonei
    • Brenner's tumor
    • Meig's syndrome
    • Krukenberg tumor
    • Stromal ovarii

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    Gastrointestinal System Questions PDF

    Description

    Test your knowledge on various gastrointestinal disorders including gastric carcinoma risk factors, celiac disease features, duodenal ulcer complications, and more. This quiz covers key aspects and complications associated with these conditions.

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