Gastrointestinal System Questions PDF

## Gastrointestinal System Questions ### 610. Which of the following does NOT predispose to Gastric Carcinoma: - Infection with H. Pylori - Cigarette Smoking - Hypochlorhydria - **Pyloric Stenosis** - Smoked & Salted Foods ### 611. Which of the following is NOT seen in Celiac Disease: - Atrophy...

## Gastrointestinal System Questions ### 610. Which of the following does NOT predispose to Gastric Carcinoma: - Infection with H. Pylori - Cigarette Smoking - Hypochlorhydria - **Pyloric Stenosis** - Smoked & Salted Foods ### 611. Which of the following is NOT seen in Celiac Disease: - Atrophy of Villi - **Epitheloid Granuloma** - Loss of Microvillous Brush Border - Elongated Crypts - Infiltration of Lamina Propria by Plasma Cells and Lymphocytes ### 614. Which of the following is NOT a known complication of Duodenal Ulcers: - Bleeding - Malignant Transformation - Perforation - Obstruction - **Pyloric Stenosis** ### 617. Squamous Carcinoma of the Oesophagus is associated with the following EXCEPT: - High Incidence in Blacks - Alcoholism - Tobacco Usage - **H. Pylori Infection** - Plummer-Vinsion Syndrome ### 626. The following are associated with Mallory-Weiss Syndrome (oesophageal laceration) EXCEPT: - Severe Retching - Alcoholism - Excessive Vomiting - Haematemesis - **Squamous Carcinoma** ### 628. The following are features of Autoimmune Gastritis EXCEPT: - Auto Antibodies to Gastric Parietal - Association with Hashimoto Thyoiditis - Gastric Mucosal Atrophy - **Hyperacidity** - Intestinal Metaplasia ### 629. Which of the following is NOT associated with Barrett's Oesophagus: - Gastrointestinal Bleeding - Reflux Oesophagitis - **Keratinizing Squamous Carcinoma** - Long History of Heart Burn - Epithelial Dysplasia ### 630. Which of the following is NOT associated with Acute Gastritis: - Severe Stress - Shock - Excessive Alcohol Consumption - **Crohn's Disease** - Excessive use of Aspirin ### 636. The following are risk factors for Colo-Rectal Cancer EXCEPT: - Low Fibre Diet - Familial Polyposis Coli - **Intestinal Amoebiasis** - High Cholesterol Intake - Obesity ### 639. Which of the following is NOT a feature of Appendiceal Carcinoids: - Can be Asymptomatic - Can be detected incidentally - **No remarkable Pleomorphism or Mitotic Activity** - Can Metastasize to the Liver - Always cause Carcinoid Syndrome ### 640. The following are features of Ulcerative Colitis EXCEPT: - Well Defined Epitheloid Granuloma - Pseudopolyps - Crypt Abscesses - Ulcers along Long Axis of Colon - **Completely Normal Serosal Surface** ### 641. The following are features of Crohn's Disease EXCEPT: - Skip Areas - Transmural Inflammation - Non-Caseating Granuloma - **Megacolon** - Cobblestone Appearance ### 644. Which of the following is NOT true about Diverticular Disease (colonic diverticulosis): - Most common is Sigmoid Colon - Risk Factor for Carcinoma - Occurs alongside Taeni coli - **There is focal weakness in the Colonic Wall** - ### 645. Which of the following is NOT true about Retroperitoneal Fibrosis: - Causes Obliteration of the Ureters - **Encircles Abdominal Aorta** - Shows a Prominent Lymphocyte Infiltrate - Reported following administration of Methysergide & other medicine - Develops into well differentiated Fibrosarcoma ### 646. Which of the following is NOT an Extraintestinal manifestation of Crohn's Disease: - Polyarthritis - Ankylosing Spondylitis - **Cholecystitis** - Erythema Nodosum - Uveitis ### 650. Which of the following is NOT a necessary component of Cirrhosis of the Liver: - **Fibrosis** - Nodules of Regenerating Liver Cells - Active (acute) Inflammatory Process with Piece Meal Necrosis - Distortion of Entire Liver Architecture - Distortion of Intrahepatic Blood Flow ### 651. Crohn's Disease (regional enteritis) is associated with each of the following Extraintestinal manifestations EXCEPT: - Pernicious Anemia - Uveitis - Ankylosing Spondylitis - **Rheumatic Carditis** - Erythema Nodosum ### 654. Which of the following diseases is likely to be complicated by Malignancy: - Familial Polyposis Coli - **Crohn's Disease** - Ulcerative Colitis - Chronic Duodenal Ulcer - H. Pylori Gastritis ### 655. Which of the following Uterine Lesions has a greatest potential to evolve into carcinoma: - Simple Hyperplasia - **Complex Hyperplasia with Atypia** - Submucosal Fibroid - Intramural Fibroid ### 657. All of the following GI diseases have been shown to be associated with an increased incidence of Malignancy EXCEPT: - Achalasia - Celiac Sprue - Whipple's Disease - Crohn's Disease (regional enteritis) - **Ulcerative Colitis ** ### 658. In Chronic Idiopathic Ulcerative Colitis, which of the following is/are usually found: - Fistula-in-Ano - Linear Serpiginous Ulcers - **Both A & B** - Neither A nor B ### 659. Which of the following is MOST characteristic of Crohn's Disease as compared with Ulcerative Colitis: - Tends to occur in Young Adults - Tends to involve the Mucosa continuously - Involves the Colon Wall Transmurally - **May occur in both the Large & Small Intestine** - Increases the probability of developing cancer ### 660. Which of the following is the commonest cause of Subarachnoid Hemorrhage: - **Rupture of Berry Aneurysm** - Rupture of Vascular Malformation - Blood Dyscrasia - Polyarteritis Nodosa - Tertiary Syphilis ### 661. Increased Maximal Gastric Acid Output is seen in: - Pernicious Anemia - Gastric Carcinoma - **Zollinger-Ellison Syndrome** - Aging - None of the Above ### 666. Which of the following is least likely to be complicated by Colorectal Carcinoma: - Familial Adenomatous Polyposis Coli - Villous Adenoma - **Tubular Adenoma** - Hyperplastic Polyps - Ulcerative Colitis ### 669. Which of the following is NOT associated with Sjorgen's Syndrome: - Autoimmune Aetiology - Affects Salivary and Lacrimal Glands - Associated with Hypergammaglobulinemia - Can develop into Epithelial Carcinoma - **Associated with Rheumatoid Arthritis** ### 670. Which of the following is associated with Salivary Gland Calculi: - Sjogren's Syndrome - Mumps - Salivary Gland Carcinoma - Suppurative Parotitis - Adenoid Cystic Carcinoma ### 671. The following are true about Pleomorphic Salivary Gland Adenoma EXCEPT: - Arise most commonly in Parotids - Well Circumscribed but have extension in adjacent tissues - Composed of epithelial and mesenchymal elements - **Commonly (more than 50%) become Malignant** - Most Common Salivary Gland Tumor ### 673. Which of the following is NOT true about Plummer-Vinson Syndrome: - Transverse Folds of Mucosa of Oesophagus - Associated with Megaloblastic Anemia - More common in Females - **Increased Incidence of Carcinoma** - Can be visualized by Radiologist during Barium Swallow ### 674. Barrett's Esophagus is: - **Metaplasia of Oesophageal Squamous Epithelium** - A Web formed of Folded Mucosa - A Pulsion Diverticulum - In-Situ Carcinoma of the Oesophagus - Oesophageal Candidiasis ### 675. Which of the following is true about Hypertrophic Pyloric Stenosis: - Commonly affects Females - **Usually presents at age 5 years** - Obstruction is caused by Hamartoma of Mucosa - The Pyloric Muscle is greatly thickened - Predispose to Chronic Peptic Ulcer ### 676. Which of the following is NOT a Gastric Mucosa Protection mechanism: - Mucus Secretion - Bicarbonate secretion - **Bacterial Flora** - Epithelial Barrier - Prostaglandin ### **685. Which of the following is true about Ulcerative Colitis:** - Inflammation is Transmural - The disease is characterized by Skip Lesions - Affects all parts of GIT - Crypt Abscesses are frequently seen - Non-Caseating Granulomas are seen ### 686. Estimation of which of the following is used for the diagnosis of Carcinoid Syndrome: - **Urinary 5HIAA** - Urinary VMA - Urinary Amino Acids - Urinary Serotonin - Urinary Gastrin ### 687. Which of the following is true about Crohn's Disease: - **Inflammation is Transmural** - Only affects Small & Large Intestine - Commonly complicated by Malignancy - Is not a cause of Malabsorption - Is not associated with Extraintestinal Lesions ### 688. Gastric Lymphoma is a known complication of: - Zollinger-Ellison Syndrome - Autoimmune Gastritis - **Gastric Crohn's Disease** - H. Pylori associated Gastritis - Peutz-Jegher Syndrome ### 689. The following are features of Crohn's Disease EXCEPT: - Skip Lesions - Deep Fissures - Granuloma Formation - Fistula - **High Incidence of Malignancy** ### 689. Which of the following bears the highest risk of Malignant Complication: - Crohn's Disease - **Familial Polyposis Coli** - Ulcerative Colitis - Celiac Disease - Villous Adenoma of Rectum ### 690. String Sign in Radiology is seen in: - Carcinoma of Oesophagus - Achalasia - **Hypertrophic Pyloric Stenosis** - Crohn's Disease - Hirschsprung Disease ### 709. Non-Caseating Granulomas are seen in all of the following EXCEPT: - Crohn's Disease - **Ulcerative Colitis** - Primary Biliary Cirrhosis - Temporal Arteritis - Sarcoidosis ### 713. Which of the following Malignant Tumors is most likely to be found in the Jejunum: - Squamous Cell Carcinoma - **Adenocarcinoma** - Clear Cell Carcinoma - Lymphoma - Fibrosarcoma ### 714. Which of the following most likely arise as a complication of Gastric Adenocarcinoma: - Barret Mucosa - Cushing Syndrome - **Krukenberg Tumor** - Oesophageal Varices - Primary Sclerosing Cholangitis ### 715. Which of the following Bone Lesions is associated with Café-au-Lait Skin Pigmentation and Endocrinopathy: - Osteomalacia - Osteopetrosis - Osteogenesis Imperfecta - **Polystitic Fibrous Dysplasia** - Anuerysmal Bone Cyst ### 722. Which of the following is associated with Ulcerative Colitis: - Acute Pancreatitis - Fistula Formation - H. pylori associated Gastritis - **Primary Sclerosing Cholangitis** - Primary Biliary Cirrhosis ### 730. Estimation of level CEA (Carcino-Embryonic Antigen) is most helpful in: - Diagnosis of Pre-Invasive Colo-Rectal Cancer - Diagnosis of Metastatic Colo-Rectal Carcinoma - **Post-Surgical Follow-up of Colo-Rectal Cancer** - Malignant Change in Ulcerative Colitis - Malignant Change in Crohn's Disease ### 732. Cobble-Stone appearance is seen in: - Ulcerative Colitis - Ischemic Colitis - **Crohn's Disease** - Non-Familial Polyposis - Diverticulitis ### 737. Crypt Abscesses, Pseudopolyps and Broad-Based Ulcer are seen in: - Intestinal Schistosomiasis - Intestinal Amoebiasis - Crohn's Disease - **Ulcerative Colitis** - Enteric Fever ### 738. Which of the following Cardiac Lesions is most likely to develop in a patient who has advanced Carcinoma of the Pancreas: - Dilated Cardiomyopathy - **Non-Bacterial Thrombotic Endocarditis** - Acute Fibrimous Pericarditis - Endocardial Fibrosis - Obstruction of Right Outflow Tract ### 741. Which of the following has the highest risk for Colo-Rectal Carcinoma: - Ulcerative Colitis - Crohn's Disease - **Familial Polyposis Coli ** - Non-Familial Polyposis - Diverticulosis ### 747. Which of the following is NOT strongly associated with Smoking: - Thromboangitis Obliterans - Atherosclerosis - **Type B- Chronic Gastritis** - Renal Cell Carcinoma - Impotence ### 754. Which of the following is likely to be associated with a Flattened Gastric Mucosa with No Acute Ulceration: - Diet high in Nitrites - Hyperchlorahydria - Hypoparathyroidism - Menetrier Disease - **Autoantibodies to Parietal Cells** ### 758. Crypt Abscesses, Fissures, Serpentine Ulcer & Granulomas are seen in: - Intestinal Schistosomiasis - Intestinal Amoebiasis - **Crohn's Disease** - Ulcerative Colitis - Enteric Fever ### 767. Which of the following Large Intestinal Polyps carries the highest risk for cancer: - Tubular Adenoma smaller than 1cm in Diameter - Schistosomal Inflammatory Polyp - Hyperplastic Polyp - **Sessile Villous Adenoma larger than 4cm in Diameter** - Juvenile Polyp+-- ### 779. The following is NOT TRUE about Crohn's Disease: - Transmural Involvement of Bowel - Non-Caseating Granulomas - Formation of Fistula - Cobblestone appearance of Mucosa - **The disease is limited to the Terminal Ileum** ### 780. Which of the following is associated with Ulcerative Colitis: - Primary Biliary Cirrhosis - Secondary Biliary Cirrhosis - Hepatic Adenoma - **Primary Sclerosing Cholangitis** - Hepatic Granuloma ### 787. Which of the following morpholgic features are NOT SEEN in Ulcerative Colitis: - **Non-Caseating Granulomas** - Pesudopolyps - Toxic Megacolon - Crypt Abscesses ### 804. Pseudomyxoma Peritonei is most closely associated with: - **Mucinous Cystadenoma** - Granulosa Cell Tumor - Endometroid Carcinoma - Dysgerminoma - Hilus Cell Tumor ### 816. Steatorrhea is NOT associated with: - Celiac Disease - Liver Cirrhosis - Giardiasis - **Obstructive Jaundice** - Chronic Intestinal Schistosomiasis ### 832. Which of the following is associated with Carcinoma of the Head of the Pancreas: - Dilated Cardiomyopathy - **Non-Bacterial Thrombotic Endocarditis** - Acute Fibrinous Pericarditis - Endocardial Fibrosis - Acute Myocardial Infarction ### 880. The following are features of an Acute Gastric Ulcer EXCEPT: - Found Anywhere in the Stomach - Usually Multiple - Usually Small, Less than 1 cm - Adjacent Mucosa is not remarkable - **Heals with Fibrosis** ### 883. The most significant criteria for the histological diagnosis of Barrett's Esopgahus: - Presence of Lamina Propria Papillae in the Upper 1/3rd of Epithelim - Neutrophil Inflammatory Infiltrate - Presence of Goblet Cells - Hyperkeratosis and Acanthosis of Squamous Epithelium - **All of the Above** ### 88. The Histiological Components of Pleomorphic Salivary Gland Adenoma are: - Glandular Structures - Solid Nests of Epithelial Cells - Foci of Cartilagenous Metaplasia - Mayxomatous Stroma - **All of the Above** ### 885. White Plaques in the Oral Cavity of 3 days duration in a Child 8 months old are most likely: - Snail Track Ulcers - Mucosal Leishmaniasis - Burkitt's Lymphoma - **Oral Candidiasis** - Bullous Pemphagoid ### 898. Gastric Signet Cell Carcinoma metastasizing to both ovaries is: - Pseudomyxoma Peritonei - Brenner's Tumor - Meig's Syndrome - **Krukenberg Tumor** - Stroma Ovarii