Podcast
Questions and Answers
Which receptor is targeted by ondansetron and granisetron?
Which receptor is targeted by ondansetron and granisetron?
- 5-HT3 receptor (correct)
- D2 receptor
- Muscarinic receptor
- H1 receptor
What is the mechanism of action of chlorpromazine and prochlorperazine in treating vomiting?
What is the mechanism of action of chlorpromazine and prochlorperazine in treating vomiting?
- Agonizing D2 receptor
- Activating H1 receptor
- Blocking muscarinic receptor
- Antagonizing 5-HT3 receptor (correct)
What triggers the release of mediators like 5-HT from enterochromaffin cells in the GI tract, leading to vagal afferent signaling?
What triggers the release of mediators like 5-HT from enterochromaffin cells in the GI tract, leading to vagal afferent signaling?
- Antacids
- Toxins (correct)
- Antibiotics
- Opioids
Which type of receptor does alosetron primarily affect?
Which type of receptor does alosetron primarily affect?
What is the primary mechanism of action of chlorpromazine in treating severe nausea and vomiting?
What is the primary mechanism of action of chlorpromazine in treating severe nausea and vomiting?
Which medication is primarily an H1 receptor antagonist and is used for motion sickness and pregnancy-associated vomiting?
Which medication is primarily an H1 receptor antagonist and is used for motion sickness and pregnancy-associated vomiting?
What is the main mechanism of action of domperidone in gastrointestinal disorders?
What is the main mechanism of action of domperidone in gastrointestinal disorders?
Which class of drugs primarily block substance P signalling in treating gastrointestinal disorders?
Which class of drugs primarily block substance P signalling in treating gastrointestinal disorders?
What can release mediators like 5-HT from enterochromaffin cells, triggering vagal afferent signalling leading to vomiting and nausea?
What can release mediators like 5-HT from enterochromaffin cells, triggering vagal afferent signalling leading to vomiting and nausea?
Which class of drugs acts as a competitive antagonist of all H2 receptors?
Which class of drugs acts as a competitive antagonist of all H2 receptors?
Which antidiarrheal agent acts directly on enterochromaffin-like cells and stimulates mucin secretion?
Which antidiarrheal agent acts directly on enterochromaffin-like cells and stimulates mucin secretion?
Which antidiarrheal agent is known to cause gynaecomastia and reduce cAMP levels?
Which antidiarrheal agent is known to cause gynaecomastia and reduce cAMP levels?
Which antidiarrheal agent is indicated to avoid during pregnancy due to its potential to stimulate uterine contractions?
Which antidiarrheal agent is indicated to avoid during pregnancy due to its potential to stimulate uterine contractions?
Which antidiarrheal agent is an analogue of prostaglandin E1 and promotes healing of ulcers?
Which antidiarrheal agent is an analogue of prostaglandin E1 and promotes healing of ulcers?
Which antidiarrheal agent is known to irreversibly bind to the proton pump and stop H+ movement into the stomach lumen?
Which antidiarrheal agent is known to irreversibly bind to the proton pump and stop H+ movement into the stomach lumen?
Which antidiarrheal agent can chelate and inhibit absorption of other drugs, and should be avoided for patients with impaired renal function?
Which antidiarrheal agent can chelate and inhibit absorption of other drugs, and should be avoided for patients with impaired renal function?
Which antidiarrheal agent acts by neutralizing acids to inhibit the activity of peptic enzymes and promote healing of ulcers?
Which antidiarrheal agent acts by neutralizing acids to inhibit the activity of peptic enzymes and promote healing of ulcers?
Which antidiarrheal agent can be taken with simeticone to reduce bloating?
Which antidiarrheal agent can be taken with simeticone to reduce bloating?
Which antidiarrheal agent stimulates bicarbonate secretion and prevents gastric damage due to chronic NSAID use?
Which antidiarrheal agent stimulates bicarbonate secretion and prevents gastric damage due to chronic NSAID use?
Which antidiarrheal agent is a competitive antagonist of all H2 receptors, well absorbed orally, and may cause thrombocytopenia as an adverse effect?
Which antidiarrheal agent is a competitive antagonist of all H2 receptors, well absorbed orally, and may cause thrombocytopenia as an adverse effect?
Which antidiarrheal agent has a short half-life but effects that last 2-3 days, and should be avoided for patients with liver disease or those who are pregnant/breastfeeding?
Which antidiarrheal agent has a short half-life but effects that last 2-3 days, and should be avoided for patients with liver disease or those who are pregnant/breastfeeding?
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