Gastroesophageal Reflux Disease (GERD) and TLC Quiz

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What diagnostic procedure should be performed in individuals with swallowing or breathing issues related to GERD?

Echocardiogram

Upper endoscopy (correct)

CT scan of the chest

MRI of the esophagus

Which symptom is NOT commonly associated with GERD?

Heartburn

Chest pain

Regurgitation

Shortness of breath (correct)

What is the recommended treatment for individuals with erosive esophagitis due to GERD?

Proton pump inhibitors (PPIs) (correct)

Antacids

Antibiotics

H2 blockers

What is the mechanism of action of H2 blockers in the treatment of GERD?

Competitive inhibition of histamine at H2 receptors of the gastric parietal cells Signup and view all the answers

What lifestyle change is recommended for individuals with nocturnal GERD?

Elevating the head of the bed Signup and view all the answers

What are examples of trigger foods for individuals with GERD?

Chocolate, caffeine, alcohol, acidic food, spicy food Signup and view all the answers

Which medication is no longer the preferred agent for treating GERD?

Cimetidine (Tagamet) Signup and view all the answers

What is the mechanism of action of proton pump inhibitors (PPIs) in suppressing gastric acid secretion?

Inhibit the parietal cell H+/K+ ATP pump Signup and view all the answers

What are the concerns associated with proton pump inhibitor (PPI) use?

Increased risk of chronic kidney disease Signup and view all the answers

Which antibiotic is a macrolide and a CYP 3A4 inhibitor?

Clarithromycin (Biaxin) Signup and view all the answers

What is the mechanism of action of amoxicillin in inhibiting bacterial cell wall synthesis?

Inhibits bacterial cell wall synthesis by binding to PBPs Signup and view all the answers

What is the main concern associated with metronidazole use?

Neurological side effects with alcohol consumption Signup and view all the answers

Which antibiotic should not be used in children due to its salicylate component?

Bismuth Subsalicylate (Pepto-Bismol) Signup and view all the answers

What is the mechanism of action of bismuth subsalicylate in peptic ulcer treatment?

Provides antisecretory effect through bismuth Signup and view all the answers

What do proton pump inhibitors (PPIs) decrease the absorption of?

Vitamin B12 Signup and view all the answers

What are the typical side effects associated with proton pump inhibitors (PPIs)?

Headache and abdominal pain Signup and view all the answers