Gastroesophageal Reflux Disease (GERD) and TLC Quiz

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Questions and Answers

What diagnostic procedure should be performed in individuals with swallowing or breathing issues related to GERD?

  • Echocardiogram
  • Upper endoscopy (correct)
  • CT scan of the chest
  • MRI of the esophagus

Which symptom is NOT commonly associated with GERD?

  • Heartburn
  • Chest pain
  • Regurgitation
  • Shortness of breath (correct)

What is the recommended treatment for individuals with erosive esophagitis due to GERD?

  • Proton pump inhibitors (PPIs) (correct)
  • Antacids
  • Antibiotics
  • H2 blockers

What is the mechanism of action of H2 blockers in the treatment of GERD?

<p>Competitive inhibition of histamine at H2 receptors of the gastric parietal cells (D)</p> Signup and view all the answers

What lifestyle change is recommended for individuals with nocturnal GERD?

<p>Elevating the head of the bed (A)</p> Signup and view all the answers

What are examples of trigger foods for individuals with GERD?

<p>Chocolate, caffeine, alcohol, acidic food, spicy food (A)</p> Signup and view all the answers

Which medication is no longer the preferred agent for treating GERD?

<p>Cimetidine (Tagamet) (D)</p> Signup and view all the answers

What is the mechanism of action of proton pump inhibitors (PPIs) in suppressing gastric acid secretion?

<p>Inhibit the parietal cell H+/K+ ATP pump (C)</p> Signup and view all the answers

What are the concerns associated with proton pump inhibitor (PPI) use?

<p>Increased risk of chronic kidney disease (A)</p> Signup and view all the answers

Which antibiotic is a macrolide and a CYP 3A4 inhibitor?

<p>Clarithromycin (Biaxin) (D)</p> Signup and view all the answers

What is the mechanism of action of amoxicillin in inhibiting bacterial cell wall synthesis?

<p>Inhibits bacterial cell wall synthesis by binding to PBPs (D)</p> Signup and view all the answers

What is the main concern associated with metronidazole use?

<p>Neurological side effects with alcohol consumption (D)</p> Signup and view all the answers

Which antibiotic should not be used in children due to its salicylate component?

<p>Bismuth Subsalicylate (Pepto-Bismol) (D)</p> Signup and view all the answers

What is the mechanism of action of bismuth subsalicylate in peptic ulcer treatment?

<p>Provides antisecretory effect through bismuth (D)</p> Signup and view all the answers

What do proton pump inhibitors (PPIs) decrease the absorption of?

<p>Vitamin B12 (C)</p> Signup and view all the answers

What are the typical side effects associated with proton pump inhibitors (PPIs)?

<p>Headache and abdominal pain (A)</p> Signup and view all the answers

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