Gastroesophageal Reflux Disease (GERD) Diagnosis and TLC Quiz

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What are the symptoms of GERD?

Heartburn, regurgitation, noncardiac chest pain

When should upper endoscopy be performed for GERD diagnosis?

In those who have issues swallowing or breathing

What are the TLC (therapeutic lifestyle changes) recommendations for GERD?

Weight loss in those who are overweight or have had recent weight gain; elevating the head of the bed and avoiding meals 2-3 hours before bed for those with nocturnal GERD

Give examples of trigger foods for GERD.

Chocolate, caffeine, alcohol, acidic food, spicy food Signup and view all the answers

What is the drug of choice for treating GERD?

Proton pump inhibitors (PPIs) Signup and view all the answers

How long should a course of PPIs be for those with erosive esophagitis?

8 weeks Signup and view all the answers

When should PPIs be continued for GERD patients?

In those who have continued symptoms after stopping PPI therapy and in those with erosive or Barrett’s esophagus Signup and view all the answers

What is the mechanism of action of H2 Blockers?

Competitive inhibition of histamine at H2 receptors of the gastric parietal cells, which inhibits gastric acid secretion Signup and view all the answers

What are the concerns associated with H2 Blockers?

The body can overcome H2-blockers by producing more histamine Signup and view all the answers

What is the most commonly used H2-blocker for treating GERD?

Famotidine (Pepcid) Signup and view all the answers

What is the mechanism of action of PPIs?

Suppress gastric basal and stimulated acid secretion by inhibiting the parietal cell H+/K+ ATP pump Signup and view all the answers

What are the concerns associated with PPI use?

Decrease the absorption of substances that depend on acidic environments; increased risk for pneumonia, C. diff., and B12 deficiency Signup and view all the answers

Name a PPI that has been associated with chronic kidney disease.

Esomeprazole (Nexium) Signup and view all the answers

Which antibiotic is a macrolide and inhibits RNA-dependent protein synthesis?

Clarithromycin (Biaxin) Signup and view all the answers

What is the main concern associated with Metronidazole use?

NO ALCOHOL while taking and for 3 days after stopping the medication Signup and view all the answers

What is the mechanism of action of Misoprostol?

Synthetic prostaglandin E1 analog that replaces the protective prostaglandins consumed with prostaglandin-inhibiting therapies Signup and view all the answers

What is the main purpose of using Antacids?

Neutralizing acid by binding to gastric acid to form a salt and water Signup and view all the answers

How does Sucralfate work?

Forms complex gels with normal and necrotic mucosa to protect the cells from damage from acid Signup and view all the answers

What is the only OTC Nausea Med mentioned in the text?

Emetrol Signup and view all the answers

What is the mechanism of action of Promethazine (Phenergan)?

Act by blocking dopamine receptors in the brainstem Signup and view all the answers

What are the concerns associated with using Bismuth Subsalicylate in children?

Not to be used in children because of salicylate part Signup and view all the answers

What is the mechanism of action of H2-blockers?

Inhibit the parietal cell H+/K+ ATP pump (C) Signup and view all the answers

What is the main concern associated with Metronidazole use?

Metallic taste and disulfiram-like reaction (B) Signup and view all the answers

What are the concerns associated with using Bismuth Subsalicylate in children?

Not to be used in children due to salicylate content (A) Signup and view all the answers

What is the mechanism of action of Misoprostol?

Replaces the protective prostaglandins consumed with prostaglandin-inhibiting therapies (C) Signup and view all the answers

What is the only OTC Nausea Med mentioned in the text?

Emetrol (A) Signup and view all the answers

What are the symptoms of GERD?

Heartburn, regurgitation, chest pain (D) Signup and view all the answers

What antibiotic is a macrolide and inhibits RNA-dependent protein synthesis?

Clarithromycin (D) Signup and view all the answers

How does Sucralfate work?

Forms complex gels with normal and necrotic mucosa to protect the cells from damage from acid (B) Signup and view all the answers

What is the main purpose of using Antacids?

Neutralizes acid by binding to gastric acid to form a salt and water (no receptor needed) (B) Signup and view all the answers

What is the most commonly used H2-blocker for treating GERD?

Famotidine (Pepcid) (D) Signup and view all the answers

What is the drug of choice for treating GERD?

Proton Pump Inhibitors (PPIs) (A) Signup and view all the answers

What is the most common symptom of Gastroesophageal Reflux Disease (GERD)?

Heartburn (D) Signup and view all the answers

What is the drug of choice for treating GERD?

Proton Pump Inhibitors (PPIs) (B) Signup and view all the answers

What is the recommended course of PPIs for those with erosive esophagitis?

8-week course (B) Signup and view all the answers

What are some trigger foods for GERD that patients should be aware of?

Chocolate, caffeine, and alcohol (B) Signup and view all the answers

What is the mechanism of action of H2 Blockers used for treating GERD?

Inhibition of gastric acid secretion (A) Signup and view all the answers

What are the potential side effects of H2 Blockers?

Dizziness and headache (A) Signup and view all the answers

In whom should upper endoscopy be performed for GERD diagnosis?

Only those with difficulty swallowing or breathing (C) Signup and view all the answers

What lifestyle change is recommended for those with nocturnal GERD?

Avoiding meals 2-3 hours before bed (B) Signup and view all the answers

What is the main concern associated with prolonged use of PPIs?

Chronic kidney disease (B) Signup and view all the answers

What is the main mechanism of action of Proton Pump Inhibitors (PPIs)?

Inhibition of proton transport in the gastric parietal cells (C) Signup and view all the answers

What is a recommended therapeutic lifestyle change (TLC) for those with GERD?

Elevating the head of the bed for better sleep posture (C) Signup and view all the answers

What is the concern associated with prolonged use of H2 Blockers?

The body can overcome H2-blockers by producing more histamine (C) Signup and view all the answers

What is the mechanism of action of H2 blockers used for treating GERD?

Suppress gastric basal and stimulated acid secretion by inhibiting the parietal cell H+/K+ ATP pump (A) Signup and view all the answers

What are the concerns associated with prolonged use of H2 blockers?

Decreased absorption of substances that depend on acidic environments (B) Signup and view all the answers

What is the main concern associated with Metronidazole use?

NO ALCOHOL while taking and for 3 days after stopping the medication (D) Signup and view all the answers

What is the main mechanism of action of Proton Pump Inhibitors (PPIs)?

Inhibit the parietal cell H+/K+ ATP pump (B) Signup and view all the answers

What is the mechanism of action of Misoprostol?

Synthetic prostaglandin E1 analog that replaces the protective prostaglandins consumed with prostaglandin-inhibiting therapies (B) Signup and view all the answers

What is the most common symptom of Gastroesophageal Reflux Disease (GERD)?

Heartburn (D) Signup and view all the answers

What are the symptoms of GERD?

Heartburn, regurgitation, chest pain, difficulty swallowing (C) Signup and view all the answers

What is the recommended course of PPIs for those with erosive esophagitis?

12 weeks (A) Signup and view all the answers

What is the main purpose of using Antacids?

Neutralize acid by binding to gastric acid to form a salt and water (no receptor needed) (C) Signup and view all the answers

What are some trigger foods for GERD that patients should be aware of?

Fatty foods, spicy foods, citrus fruits, chocolate, mint, garlic, onions, coffee, alcohol (C) Signup and view all the answers

What is a recommended therapeutic lifestyle change (TLC) for those with GERD?

Avoiding smoking and alcohol consumption (B) Signup and view all the answers

What is the first-line treatment for GERD?

Proton pump inhibitors (PPIs) (D) Signup and view all the answers

What is the recommended course of PPIs for those with erosive esophagitis?

8-week course (B) Signup and view all the answers

What is the main mechanism of action of H2 Blockers used for treating GERD?

Competitive inhibition of histamine at H2 receptors of the gastric parietal cells (B) Signup and view all the answers

What lifestyle change is recommended for those with nocturnal GERD?

Avoiding meals 2-3 hours before bed (D) Signup and view all the answers

What are some examples of trigger foods for GERD that patients should be aware of?

Chocolate, caffeine, and alcohol (A) Signup and view all the answers

When should upper endoscopy be performed in the diagnosis of GERD?

Only when there are issues swallowing or breathing (C) Signup and view all the answers

What are the concerns associated with prolonged use of PPIs?

Kidney damage (A) Signup and view all the answers

What are the potential side effects of H2 Blockers?

Headache and diarrhea (B) Signup and view all the answers

What is the main concern associated with using Bismuth Subsalicylate in children?

Reye's syndrome (B) Signup and view all the answers

What antibiotic is a macrolide and inhibits RNA-dependent protein synthesis?

Clarithromycin (A) Signup and view all the answers

What is a potential concern with the use of H2 Blockers?

Risk of kidney damage (B) Signup and view all the answers

What is the purpose of routine global elimination of trigger foods not being recommended for GERD patients?

To avoid unnecessary dietary restrictions (A) Signup and view all the answers

Gastroesophageal Reflux Disease (GERD) Diagnosis and TLC Quiz

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Questions and Answers

What are the symptoms of GERD?

When should upper endoscopy be performed for GERD diagnosis?

What are the TLC (therapeutic lifestyle changes) recommendations for GERD?

Give examples of trigger foods for GERD.

What is the drug of choice for treating GERD?

How long should a course of PPIs be for those with erosive esophagitis?

When should PPIs be continued for GERD patients?

What is the mechanism of action of H2 Blockers?

What are the concerns associated with H2 Blockers?

What is the most commonly used H2-blocker for treating GERD?

What is the mechanism of action of PPIs?

What are the concerns associated with PPI use?

Name a PPI that has been associated with chronic kidney disease.

Which antibiotic is a macrolide and inhibits RNA-dependent protein synthesis?

What is the main concern associated with Metronidazole use?

What is the mechanism of action of Misoprostol?

What is the main purpose of using Antacids?

How does Sucralfate work?

What is the only OTC Nausea Med mentioned in the text?

What is the mechanism of action of Promethazine (Phenergan)?

What are the concerns associated with using Bismuth Subsalicylate in children?

What is the mechanism of action of H2-blockers?

What is the main concern associated with Metronidazole use?

What are the concerns associated with using Bismuth Subsalicylate in children?

What is the mechanism of action of Misoprostol?

What is the only OTC Nausea Med mentioned in the text?

What are the symptoms of GERD?

What antibiotic is a macrolide and inhibits RNA-dependent protein synthesis?

How does Sucralfate work?

What is the main purpose of using Antacids?

What is the most commonly used H2-blocker for treating GERD?

What is the drug of choice for treating GERD?

What is the most common symptom of Gastroesophageal Reflux Disease (GERD)?

What is the drug of choice for treating GERD?

What is the recommended course of PPIs for those with erosive esophagitis?

What are some trigger foods for GERD that patients should be aware of?

What is the mechanism of action of H2 Blockers used for treating GERD?

What are the potential side effects of H2 Blockers?

In whom should upper endoscopy be performed for GERD diagnosis?

What lifestyle change is recommended for those with nocturnal GERD?

What is the main concern associated with prolonged use of PPIs?

What is the main mechanism of action of Proton Pump Inhibitors (PPIs)?

What is a recommended therapeutic lifestyle change (TLC) for those with GERD?

What is the concern associated with prolonged use of H2 Blockers?

What is the mechanism of action of H2 blockers used for treating GERD?

What are the concerns associated with prolonged use of H2 blockers?

What is the main concern associated with Metronidazole use?

What is the main mechanism of action of Proton Pump Inhibitors (PPIs)?

What is the mechanism of action of Misoprostol?

What is the most common symptom of Gastroesophageal Reflux Disease (GERD)?

What are the symptoms of GERD?

What is the recommended course of PPIs for those with erosive esophagitis?

What is the main purpose of using Antacids?

What are some trigger foods for GERD that patients should be aware of?

What is a recommended therapeutic lifestyle change (TLC) for those with GERD?

What is the first-line treatment for GERD?

What is the recommended course of PPIs for those with erosive esophagitis?

What is the main mechanism of action of H2 Blockers used for treating GERD?

What lifestyle change is recommended for those with nocturnal GERD?

What are some examples of trigger foods for GERD that patients should be aware of?

When should upper endoscopy be performed in the diagnosis of GERD?

What are the concerns associated with prolonged use of PPIs?

What are the potential side effects of H2 Blockers?

What is the main concern associated with using Bismuth Subsalicylate in children?

What antibiotic is a macrolide and inhibits RNA-dependent protein synthesis?

What is a potential concern with the use of H2 Blockers?

What is the purpose of routine global elimination of trigger foods not being recommended for GERD patients?

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