Gastric Variceal Hemorrhage (GVH) Key Points
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Questions and Answers

What percentage of cirrhotic patients with portal hypertension experience Gastric Variceal Hemorrhage (GVH)?

  • Between 5% and 10%
  • Between 10% and 20%
  • Between 20% and 33% (correct)
  • Less than 5%
  • How does the bleeding behavior of gastric varices (GV) typically compare to esophageal varices (EV)?

  • GV bleeds at lower portal pressures than EV (correct)
  • GV bleeds are less severe than EV
  • GV bleeds are more frequent than EV
  • GV bleeds at higher portal pressures than EV
  • Which of the following is a promising management approach for gastric variceal hemorrhage (GVH), particularly for large shunts?

  • Endoscopic coiling and glue
  • TIPS alone without B-RTO
  • TIPS with balloon-occluded retrograde transvenous obliteration (B-RTO) (correct)
  • Surgery for variceal ligation
  • What are the major reasons why TIPS often fails to control rebleeding in gastric variceal hemorrhage (GVH)?

    <p>Proximity, throughput, and recruitment issues</p> Signup and view all the answers

    What is a potential concern associated with using balloon-occluded retrograde transvenous obliteration (B-RTO) for gastric variceal hemorrhage (GVH)?

    <p>Aggravation of portal hypertension and formation of new varices</p> Signup and view all the answers

    What combination shows promise for better outcomes in managing gastric variceal hemorrhage (GVH)?

    <p>TIPS-B-RTO combination</p> Signup and view all the answers

    What is the main limitation of TIPS in managing gastric variceal hemorrhage (GVH)?

    <p>Inability to fully address gastrorenal shunts (GRS)</p> Signup and view all the answers

    What is the specific meaning of 'throughput' in the context of gastric variceal hemorrhage (GVH) and TIPS placement?

    <p>The rate at which blood flows through the TIPS shunt</p> Signup and view all the answers

    Why might gastric varices not get effectively decompressed by TIPS?

    <p>Due to the presence of large gastrorenal shunts (GRS)</p> Signup and view all the answers

    What undermines the long-term effectiveness of TIPS in gastric variceal hemorrhage (GVH) control?

    <p>The recruitment phenomenon after devascularization</p> Signup and view all the answers

    What is a preferred option for managing gastric variceal hemorrhage (GVH) due to its ability to directly target and obliterate the gastric variceal complex?

    <p>B-RTO (Balloon-occluded retrograde transvenous obliteration)</p> Signup and view all the answers

    What can potentially lead to rebleeding through alternative channels even if initial hemostasis is achieved with TIPS?

    <p>Development of large gastrorenal shunts (GRS)</p> Signup and view all the answers

    What creates new bleeding pathways, jeopardizing the initial success of TIPS in managing gastric variceal hemorrhage (GVH)?

    <p>Recruitment phenomenon after devascularization</p> Signup and view all the answers

    What contributes to the higher rebleeding rates observed with TIPS in gastric variceal hemorrhage (GVH) compared to esophageal variceal hemorrhage (EVH)?

    <p>The inability to fully address gastrorenal shunts (GRS)</p> Signup and view all the answers

    What is the main advantage of B-RTO over TIPS in managing gastric variceal hemorrhage (GVH)?

    <p>Minimizing anatomical proximity issues between gastric varices and the liver</p> Signup and view all the answers

    What determines the rate at which blood flows through the TIPS shunt in the context of gastric variceal hemorrhage (GVH)?

    <p>The rate at which blood flows through gastroneral shunts (GRS)</p> Signup and view all the answers

    What is the main reason why gastric variceal hemorrhage (GVH) is less frequent than esophageal variceal hemorrhage (EVH) but often more severe?

    <p>Gastric varices bleed at lower portal pressures due to 'downhill' drainage and large portosystemic shunts</p> Signup and view all the answers

    What concept explains why TIPS often falls short in controlling rebleeding of gastric varices compared to esophageal varices?

    <p>Proximity, throughput, and recruitment</p> Signup and view all the answers

    What intervention emerges as a preferred option for managing gastric variceal hemorrhage (GVH) due to its high technical and clinical success rates as well as low GV rebleed rates?

    <p>Balloon-occluded retrograde transvenous obliteration (B-RTO)</p> Signup and view all the answers

    What potential concern is associated with using balloon-occluded retrograde transvenous obliteration (B-RTO) for gastric variceal hemorrhage (GVH)?

    <p>Aggravation of portal hypertension and emergence of new varices</p> Signup and view all the answers

    What determines the rate at which blood flows through the TIPS shunt in the context of gastric variceal hemorrhage (GVH)?

    <p>'Throughput' of blood flow</p> Signup and view all the answers

    What contributes to the higher rebleeding rates observed with TIPS in gastric variceal hemorrhage (GVH) compared to esophageal variceal hemorrhage (EVH)?

    <p>'Proximity' and 'recruitment' issues</p> Signup and view all the answers

    What is the specific meaning of 'proximity' in the context of gastric variceal hemorrhage (GVH) and TIPS placement?

    <p>The anatomical distance of gastric varices from the liver compared to esophageal varices</p> Signup and view all the answers

    What contributes to the higher rebleeding rates observed with TIPS in gastric variceal hemorrhage (GVH) compared to esophageal variceal hemorrhage (EVH)?

    <p>The inability of TIPS to fully address gastrorenal shunts (GRS)</p> Signup and view all the answers

    Why might gastric varices not get effectively decompressed by TIPS?

    <p>Direct draining of blood into the systemic circulation by large gastrorenal shunts</p> Signup and view all the answers

    What is a potential concern associated with using balloon-occluded retrograde transvenous obliteration (B-RTO) for gastric variceal hemorrhage (GVH)?

    <p>Potential occurrence of rebleeding through alternative channels</p> Signup and view all the answers

    What is the main limitation of TIPS in managing gastric variceal hemorrhage (GVH)?

    <p>Anatomical placement and inability to fully address GRS and neovascularization</p> Signup and view all the answers

    What determines the rate at which blood flows through the TIPS shunt in the context of gastric variceal hemorrhage (GVH)?

    <p>Throughput</p> Signup and view all the answers

    How does the bleeding behavior of gastric varices (GV) typically compare to esophageal varices (EV)?

    <p>Gastric varices remain under higher pressure due to distance and competing GRS</p> Signup and view all the answers

    What can potentially lead to rebleeding through alternative channels even if initial hemostasis is achieved with TIPS?

    <p>Recruitment phenomenon undermining the long-term effectiveness of TIPS</p> Signup and view all the answers

    What is a promising management approach for gastric variceal hemorrhage (GVH) due to its ability to directly target and obliterate the gastric variceal complex?

    <p>Balloon-occluded retrograde transvenous obliteration (B-RTO)</p> Signup and view all the answers

    What combination shows promise for better outcomes in managing gastric variceal hemorrhage (GVH)?

    <p>Proximity, throughput, and recruitment</p> Signup and view all the answers

    Study Notes

    Gastric Variceal Hemorrhage (GVH)

    • 25-30% of cirrhotic patients with portal hypertension experience Gastric Variceal Hemorrhage (GVH)
    • Gastric varices (GV) tend to bleed more severely but less frequently compared to esophageal varices (EV)

    TIPS Limitations

    • TIPS often fails to control rebleeding in GVH due to large shunts and inadequate decompression of gastric varices
    • The main limitation of TIPS in managing GVH is its inability to directly target and obliterate the gastric variceal complex
    • TIPS may not effectively decompress gastric varices due to proximity and throughput issues
    • TIPS can lead to rebleeding through alternative channels even after initial hemostasis

    B-RTO Advantages

    • Balloon-occluded retrograde transvenous obliteration (B-RTO) is a promising management approach for GVH, particularly for large shunts
    • B-RTO has higher technical and clinical success rates and lower GV rebleed rates compared to TIPS
    • The main advantage of B-RTO over TIPS is its ability to directly target and obliterate the gastric variceal complex

    Gastric Variceal Hemorrhage Management

    • Combination therapy with B-RTO and TIPS shows promise for better outcomes in managing GVH
    • B-RTO emerges as a preferred option for managing GVH due to its high technical and clinical success rates and low GV rebleed rates
    • Proximity and throughput issues are key concepts that explain why TIPS often falls short in controlling rebleeding of gastric varices compared to esophageal varices

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    Description

    Learn key points about Gastric Variceal Hemorrhage (GVH) including its frequency in cirrhotic patients, severity compared to esophageal variceal hemorrhage, and differences in management from EVH.

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