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Functions of the Digestive System
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Functions of the Digestive System

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Questions and Answers

What are the functions of the digestive system?

Ingestion, Mastification, Propulsion, Mixing, Secretions, Digestion, Absorption, Elimination

List the organs and accessory organs of the digestive system mentioned in the text.

Oral cavity, Pharynx, Esophagus, Stomach, Small intestine, Large intestine, Tonsils, Salivary glands, Liver, Gallbladder, Pancreas

What is the difference between organs and accessory organs in the digestive system?

While organs like the stomach and intestines are directly involved in digestion, accessory organs like the liver and pancreas provide supportive functions like producing digestive enzymes and bile.

Describe the layers of the digestive tract.

<p>Mucosa, Submucosa, Muscularis, Serosa</p> Signup and view all the answers

What are the two types of receptors involved in the regulation of the digestive system?

<p>Mechanoreceptors and Chemoreceptors</p> Signup and view all the answers

List the endocrine glands and hormones mentioned in the content.

<p>Hypothalamus, Posterior pituitary, Anterior pituitary, Pancreas, Adrenal gland</p> Signup and view all the answers

Define growth and development as explained in the content.

<p>Growth refers to an increase in size dominated in the first 20 years of life, while development includes the biological development of stem cells into functional cells and systems, as well as the development of behavioral competence in motor skills, social, emotional, and intellectual aspects.</p> Signup and view all the answers

Define the age categories mentioned in the content.

<p>The age categories include prenatal period, infancy, perinatal, neonatal, childhood, adolescence, and adulthood divided into young adult, middle adult, and older adult stages.</p> Signup and view all the answers

Explain the different germ layers mentioned in the content.

<p>The germ layers include ectoderm, mesoderm, and endoderm, which play essential roles in the development of various tissues and organs in the human body.</p> Signup and view all the answers

What are the key physiological changes associated with the cardiovascular system?

<p>Heart rate and cardiac output changes</p> Signup and view all the answers

Dermatomes are areas of skin supplied by nerves from a single ______ root.

<p>spinal</p> Signup and view all the answers

What are some physiological changes that occur in the female body during the age of 40-60?

<p>reduced amounts of oestrogen &amp; progesterone, anxiety, hot flushes, emotional disturbances, fatigue, post-menopausal osteoporosis</p> Signup and view all the answers

Describe the anatomy of the kidney and nephrons.

<p>Anatomy of the kidney includes structures such as the hilum, cortex, medulla, renal pyramid, renal papillae, calyx, renal pelvis, ureter, renal capsule, renal fascia, and adipose tissue. Nephrons consist of the renal corpuscle, proximal convoluted tubule, loop of Henle, distal convoluted tubule, and collecting duct.</p> Signup and view all the answers

What are the three phases of swallowing?

<p>Voluntary phase, Pharyngeal phase, Oesophageal phase</p> Signup and view all the answers

Explain the physiological changes that occur to the cardiovascular system as one enters older adulthood.

<p>reduction in arterial elasticity, increased stiffness of arteries and aorta, left ventricular hypertrophy, changes in cardiac tissue, decline in cardiac output, decrease in VO2 max</p> Signup and view all the answers

List and explain the functions of the kidneys.

<p>The functions of the kidneys include excretion of toxins, regulation of blood pressure and volume, regulation of solute concentration, pH levels, and RBC synthesis.</p> Signup and view all the answers

What are the phases of stomach secretions?

<p>Cephalic phase, Gastric phase, Intestinal phase</p> Signup and view all the answers

Describe the physiological changes in the respiratory system during aging.

<p>vital capacity decrease, decrease in gas exchange, changes in lung volumes, decreased lung elasticity</p> Signup and view all the answers

Name and explain the three phases of urine production.

<p>The three phases of urine production are filtration (formation of filtrate in Bowman's capsule), tubular reabsorption (returning water and solutes to blood), and tubular secretion (removing toxic byproducts from blood to filtrate).</p> Signup and view all the answers

Name the various secretions (enzymes and hormones) of the digestive system and their roles.

<p>Examples: Amylase (breaks down carbohydrates), Lipase (breaks down lipids), Protease (breaks down proteins)</p> Signup and view all the answers

What changes occur in the urinary system with aging?

<p>reduced kidney size, decreased glomerular function, changes in nephron and collecting ducts, increased risk of dehydration</p> Signup and view all the answers

What is an enzyme, its role, and what affects its function?

<p>An enzyme is a protein catalyst that speeds up chemical reactions by breaking down macronutrients. Factors such as blood pH and body temperature can affect its function.</p> Signup and view all the answers

Describe the hormonal and autogenic mechanisms that regulate the volume and concentration of urine.

<p>Hormonal mechanisms like myogenic and tubuloglomerular control blood pressure. Autogenic mechanisms regulate the filtration and reabsorption processes in the kidneys.</p> Signup and view all the answers

How does food move through the digestive tract?

<p>Mouth -&gt; Pharynx -&gt; Esophagus -&gt; Stomach -&gt; Small Intestine -&gt; Large Intestine</p> Signup and view all the answers

Describe what a buffer is and pH.

<p>A buffer is a substance that helps maintain a stable pH by resisting changes in acidity or alkalinity. pH represents the concentration of hydrogen ions in the body.</p> Signup and view all the answers

Discuss the physiological changes in the endocrine system during aging.

<p>decrease in GH, decline in thyroid hormone, immune system decline, reduction in thymosin hormone</p> Signup and view all the answers

How are the three macronutrients (carbohydrates, proteins, lipids) absorbed?

<p>Carbohydrates are absorbed as monosaccharides, proteins are broken down into amino acids, and lipids are broken down into fatty acids and glycerol.</p> Signup and view all the answers

How does senescence affect the human body?

<p>Cells deteriorate with age, genetic traits impact homeostasis, decrease in organ mass and function</p> Signup and view all the answers

Describe the differences and similarities between the endocrine and nervous systems.

<p>Both systems regulate bodily functions but differ in speed, duration, and method of communication. Endocrine system uses hormones for longer-duration communication, while the nervous system transmits signals faster via neurons and neurotransmitters.</p> Signup and view all the answers

What are the general gas laws and how do they relate to gas behavior?

<p>Boyle's Law (volume increases -&gt; pressure decreases), Dalton's Law (total pressure of gas mixture = sum of partial pressures), Henry's Law (gas concentration x solubility coefficient = amount of gas in liquid)</p> Signup and view all the answers

Describe the different chemical messengers.

<p>Chemical messengers include autocrine (acting on the same cell), paracrine (local effects), neurotransmitters (neuronal signaling), and hormones (long-distance effects through blood circulation).</p> Signup and view all the answers

Describe the types of hormones and their secretion patterns.

<p>Hormones can be acutely (dramatic), episodically (regular intervals), or chronically (stable over time) secreted based on the body's requirements.</p> Signup and view all the answers

What are the components of blood and their functions?

<p>Plasma (55%) -- transports nutrients, hormones, and proteins; Buffy coat -- includes white blood cells for immune response; Formed elements -- red blood cells carry oxygen, platelets are involved in clotting</p> Signup and view all the answers

How are red blood cells produced?

<p>Red blood cells are produced through erythropoiesis in response to decreased blood oxygen levels.</p> Signup and view all the answers

Describe the control and stimuli of hormone secretion.

<p>Hormone secretion can be controlled by neural activation (neurotransmitter signaling), hormonal activation (inducing another hormone release), and humoral control (blood-borne molecules triggering hormone release).</p> Signup and view all the answers

What is stroke volume, cardiac output, and ejection fraction in the context of cardiac function?

<p>Stroke volume is the volume of blood ejected from the heart per beat, cardiac output is the blood volume pumped out per minute, and ejection fraction is the percentage of blood pumped out of the left ventricle per contraction.</p> Signup and view all the answers

What are the functions of skeletal muscle?

<p>Movement, heat production, posture and stability, protection, regulation of metabolism, and assistance with circulation.</p> Signup and view all the answers

What are the stages of the sliding filament theory?

<p>Exposure of binding sites, Cross bridge formation, Power stroke, Cross bridge release, ATP to ADP conversion, Recovery stroke.</p> Signup and view all the answers

Explain what a motor unit is.

<p>A motor unit consists of a motor neuron and the muscle fibers it innervates, allowing signals from the nervous system to elicit muscle contractions.</p> Signup and view all the answers

What is the role of calcium and ATP in muscular contraction?

<p>Calcium triggers muscle contractions by binding to troponin, allowing for cross-bridge formation, while ATP is essential for calcium transport and myosin head pivoting during the contraction cycle.</p> Signup and view all the answers

Explain how a bone grows in length. Describe the zones in the epiphyseal plate where growth occurs.

<p>Bone grows in length at the epiphyseal plate, which contains the zones of resting, proliferation, hypertrophy, and calcification. The chondrocytes in these zones undergo specific processes to contribute to bone growth.</p> Signup and view all the answers

Describe the three somatotypes and their characteristics.

<p>The three somatotypes are Endomorphy (relative fatness), Mesomorphy (relative musculoskeletal robustness), and Ectomorphy (relative linearity or slenderness). Each somatotype has distinct physical features associated with it.</p> Signup and view all the answers

What are the main changes that occur when females and males go through puberty?

<p>The main changes during puberty include accelerated body growth, growth of gonads, increased production of gonadal hormones, development of secondary sex characteristics like breast development in females and pubic hair growth, and the ability to reproduce.</p> Signup and view all the answers

Identify and explain the role of the major sex hormones in females and males during puberty.

<p>In females, estrogen and progesterone play key roles in the development of primary and secondary sex characteristics and the menstrual cycle. In males, testosterone is responsible for the development of male secondary sex characteristics and sperm cell production.</p> Signup and view all the answers

Explain the process of fertilization, cell division, and implantation.

<p>Fertilization involves the fusion of male and female pronuclei to form a zygote. Cell division leads to the formation of a blastocyst with an inner cell mass and trophoblast. Implantation occurs when the blastocyst burrows into the uterine wall for further development.</p> Signup and view all the answers

Describe the anatomy of the placenta and its functions.

<p>The placenta consists of maternal and fetal sides, connected by the umbilical cord. It acts as a barrier between maternal and fetal circulations, facilitating gas exchange, nutrient transfer, and waste removal between the mother and the developing fetus.</p> Signup and view all the answers

What hormonal changes occur during pregnancy and where are the hormones secreted from?

<p>During pregnancy, hormones like hCG, relaxin, progesterone, and estrogen are secreted from various sources such as the blastocyst, placenta, and ovaries. These hormones play crucial roles in supporting pregnancy and fetal development.</p> Signup and view all the answers

List and describe the changes to the cardiovascular, respiratory, renal, thermoregulatory, and endocrine systems during pregnancy.

<p>During pregnancy, cardiovascular changes include increased blood volume and cardiac output. Respiratory changes involve alterations in lung capacity. Renal changes increase urine output. Thermoregulatory changes affect metabolic rate. Endocrine changes involve adaptations in hormone levels.</p> Signup and view all the answers

Why do cardiovascular and respiratory changes occur during pregnancy?

<p>Cardiovascular changes occur to support increased blood flow to the uterus and organs. Respiratory changes assist with efficient gas exchange and oxygen delivery to meet the increased demands of the developing fetus and the pregnant woman.</p> Signup and view all the answers

Describe the physical changes that occur during pregnancy.

<p>Physical changes during pregnancy include weight gain, ligament laxity due to relaxin, altered center of gravity, increased weight of the uterus and breasts, and potential pelvic floor weakening leading to urinary incontinence and organ prolapse.</p> Signup and view all the answers

What is menopause and what are the major alterations associated with it?

<p>Menopause refers to the cessation of the menstrual cycle. Major alterations during menopause include hormonal fluctuations, changes in reproductive function, and physiological adjustments due to declining ovarian function.</p> Signup and view all the answers

Study Notes

Digestive System

  • Functions:
    • Ingestion
    • Mastification (mechanical breakdown)
    • Propulsion (movement of food down the digestive tract)
    • Mixing (mixing of food with digestive secretions)
    • Secretions (enzymes and hormones)
    • Digestion (mechanical and chemical breakdown)
    • Absorption (breakdown of nutrients)
    • Elimination (waste elimination)
  • Organs and accessory organs:
    • Oral cavity (mechanical and chemical digestion)
    • Pharynx (swallowing)
    • Esophagus (swallowing)
    • Stomach (mechanical digestion and mixing)
    • Small intestine (digestion and absorption)
    • Large intestine (water and salt absorption)
    • Tonsils (prevent infection)
    • Salivary glands (secretion of saliva)
    • Liver (bile production)
    • Gallbladder (bile storage)
    • Pancreas (digestive enzyme secretion)
  • Regulation:
    • Neural regulation (autonomic nervous system)
    • Hormonal regulation (gastrin, cholecystokinin)
    • Local regulation (mechanoreceptors, chemoreceptors)
  • Phases of swallowing:
    • Voluntary phase (food bolus moved to back of mouth)
    • Pharyngeal phase (soft palate elevates, upper sphincter relaxes)
    • Oesophageal phase (lower sphincter relaxes, food bolus moves down oesophagus)
  • Phases of stomach secretions:
    • Cephalic phase (thought, smell, and taste of food)
    • Gastric phase (enlargement of stomach, mechanoreceptors stimulate secretions)
    • Intestinal phase (chyme contains lipids, fats, and proteins, stimulates chemoreceptors)
  • Enzymes and hormones:
    • Amylase (breaks down carbohydrates)
    • Lipase (breaks down lipids)
    • Protease (breaks down proteins)
    • Gastrin (stimulates gastric acid secretion)
    • Cholecystokinin (stimulates secretion of bile and pancreatic enzymes)
  • Food movement through the digestive tract:
    • Mouth (mixed with saliva, formed into bolus)
    • Pharynx (swallowed, moved down oesophagus)
    • Stomach (mixed with gastric juices, formed into chyme)
    • Small intestine (digested and absorbed)
    • Large intestine (water and salt absorbed, formed into faeces)

Respiratory System

  • Anatomical structures:
    • External nose and nasal cavity
    • Pharynx
    • Larynx
    • Trachea
    • Bronchi and bronchioles
    • Lungs
    • Alveoli (gas exchange)
  • Zones:
    • Upper respiratory zone (nose, nasal cavity, pharynx, and larynx)
    • Lower respiratory zone (trachea, bronchi, bronchioles, and lungs)
  • Respiration:
    • Ventilation (movement of air in and out of lungs)
    • Inspiration (air moves into lungs)
    • Expiration (air moves out of lungs)
    • External respiration (exchange of gases between lungs and blood)
    • Internal respiration (exchange of gases between blood and tissues)
  • Gas laws:
    • Boyle's law (volume and pressure)
    • Dalton's law (partial pressures)
    • Henry's law (gas solubility)
  • Lung capacities and volumes:
    • Tidal volume (TV)
    • Residual lung volume (RLV)
    • Forced vital capacity (FVC)
  • Control of ventilation:
    • Mechanoreceptors (stretch receptors in lungs)
    • Peripheral chemoreceptors (aortic and carotid bodies)
    • Cortical influence (anticipation of exercise)
    • Proprioceptive reflexes (sensory input from muscles, joints, and tendons)

Cardiovascular System

  • Systems:
    • Heart
    • Arteries
    • Veins
    • Blood
  • Heart anatomy:
    • Right atrium
    • Right ventricle
    • Tricuspid valve
    • Pulmonary semilunar valve
    • Pulmonary artery
    • Pulmonary vein
    • Left atrium
    • Left ventricle
    • Bicuspid valve
    • Aortic valve
    • Aorta
  • Diastole and systole:
    • Diastole (heart relaxation, filling with blood)
    • Systole (heart contraction, ejection of blood)
  • Electrical activity:
    • Sinoatrial (SA) node (pacemaker)
    • Atrioventricular (AV) node
    • Bundle of His
    • Purkinje fibers
  • ECG:
    • P wave (atrial depolarization)
    • QRS complex (ventricular depolarization)
    • T wave (ventricular repolarization)
  • Regulation:
    • Parasympathetic nervous system (rest and digest)
    • Sympathetic nervous system (fight or flight)
  • Blood:
    • Plasma (water, proteins, nutrients, waste)
    • Buffy coat (white blood cells)
    • Formed elements (red blood cells, platelets)

Muscular System

  • Types of muscle:
    • Smooth muscle (involuntary, non-striated)
    • Cardiac muscle (involuntary, striated)
    • Skeletal muscle (voluntary, striated)
  • Functions:
    • Movement
    • Heat production
    • Posture and stability
    • Protection
    • Regulation of metabolism
    • Assistance with circulation
  • Anatomy:
    • Epimysium
    • Perimysium
    • Endomysium
    • Muscle fiber
    • Myofibril
    • Myofilaments
  • Sliding filament theory:
    • Exposure of binding sites
    • Cross-bridge formation
    • Power stroke
    • Cross-bridge release
    • Recovery stroke
  • Motor unit:
    • Motor neuron
    • Muscle fibers
  • Calcium and ATP role in muscular contraction:
    • Calcium release from sarcoplasmic reticulum
    • ATP for power stroke
    • ATP for cross-bridge release### Anatomy of the Kidney and Nephrons
  • The kidney has a hilium (opening) for nerves and renal artery to enter and for renal vein and ureter to exit
  • The outer cortex contains nephrons
  • The inner medulla contains renal pyramids and renal papillae
  • The renal capsule is a layer of connective tissue that protects the kidney
  • The renal fascia is a layer of connective tissue that helps anchor the kidney in place
  • A layer of adipose tissue provides cushioning for the kidney

Nephron Structure and Function

  • The renal corpuscle (glomerulus and Bowman's capsule) filters blood and separates waste from useful substances
  • The proximal convoluted tubule returns filtered substances back into the blood through reabsorption and secretion
  • The loop of Henle reabsorbs water and solutes
  • The distal convoluted tubule adds waste to the filtrate through reabsorption and secretion
  • The collecting duct collects fluid from the DCT and empties into the renal pelvis

Juxtaglomerular Apparatus

  • The juxtaglomerular apparatus is responsible for regulating blood volume and pressure
  • It consists of juxtaglomerular cells (smooth muscle cells around the afferent arteriole) and macula densa cells (in the DCT)

Functions of the Kidneys

  • Excretion: filtering waste and excess substances from the blood
  • Regulation of blood pressure and volume
  • Regulation of solute concentration (Na, K, Cl, Ca)
  • Regulation of pH levels (through H+ secretion)
  • Regulation of RBC synthesis (stimulating production of erythrocytes)

Phases of Urine Production

  • Filtration: small molecules and water are forced out of the blood into the Bowman's capsule
  • Tubular reabsorption: returning water and solutes back into the blood
  • Tubular secretion: movement of toxic byproducts from blood to filtrate

Hormonal and Autogenic Mechanisms of Urine Regulation

  • Myogenic mechanism regulates blood pressure
  • Tubuloglomerular mechanism regulates blood pressure and volume
  • Autonomic nervous system regulates blood pressure and volume

Endocrine and Nervous Systems

  • Both use the brain and spinal cord to regulate bodily functions
  • Endocrine system: slower speed, longer duration, transported via hormones in the circulatory system
  • Nervous system: faster speed, shorter duration, transmitted via neurotransmitters

Chemical Messengers

  • Autocrine: cell affects same cell
  • Paracrine: cell affects nearby cells via extracellular fluid
  • Neurotransmitters: produced by neurons, secreted into the synaptic cleft, influencing postsynaptic cells
  • Endocrine: hormones secreted into the bloodstream, traveling to target tissues

Hormone Secretion Patterns

  • Acute hormone secretion: irregular and dramatic
  • Episodic hormone secretion: regular intervals and concentrations
  • Chronic hormone secretion: relatively stable over a long period of time

Control and Stimuli of Hormone Secretion

  • Neural activation: hormone releases a neurotransmitter, signaling an endocrine gland to release a hormone
  • Hormonal activation: one hormone stimulates an endocrine gland to release another hormone
  • Humoral control: blood-borne molecules stimulate hormone secretion

Endocrine Glands and Hormones

  • Hypothalamus
  • Posterior pituitary
  • Anterior pituitary
  • Pancreas
  • Adrenal gland

Development and Growth

  • Growth: increase in size, dominated in the first 20 years of life
  • Development: biological, behavioral, motor skills, social, emotional, and intellectual
  • Age categories: chronological, biological, prenatal, postnatal, infancy, childhood, adolescence, adulthood

Germ Layers and Embryonic Development

  • Morula (day 4): solid ball of cells
  • Early blastocyst (day 6): hollow ball of cells with fluid-filled cavity
  • Late blastocyst (day 10): pre-embryo with embryonic disk, 2 layers of cells
  • Gastrula (day 16): embryo with 3 primary germ layers (ectoderm, mesoderm, endoderm)

Foetal Cardiovascular Anatomy and Postnatal Changes

  • Ductus arteriosus: connects pulmonary artery to aorta
  • Ductus venosus: connects umbilical vein to inferior vena cava
  • Postnatal changes: closure of foramen ovale, constriction of ductus arteriosus, and inflation of lungs### Bone Growth
  • Bone growth occurs at the epiphyseal plate (ends of bone) containing 4 zones:
    • Zone of resting: Chondrocytes (cartilage cells) do not divide
    • Zone of proliferation: Chondrocytes produce new cartilage
    • Zone of hypertrophy: Chondrocytes enlarge and mature
    • Zone of calcification: Hypertrophied chondrocytes die, blood vessels from diaphysis (middle of bone) grow, osteoblast deposits new bone matrix = bone grows
  • Epiphyseal plate ossifies (turns into bone) and becomes a line once adult size is reached

Articular Cartilage Growth

  • Articular cartilage at end of bone for protection
  • Outer cartilage similar to zone of resting
  • Inner cartilage calcified and ossifies
  • When at full size, zone stops replacing cartilage

Bone Width Growth

  • Bone is deposited by osteoblasts on outer surface (bone formation)
  • Bone is reabsorbed by osteoclasts on inner surface (bone reabsorption)
  • Bone grows in width by reabsorbing inner and forming outer

Somatotypes

  • Endomorphy (relative fatness):
    • Stocky, short thick neck, tendency to store body fat, large round body, short arms/legs
    • Calculated based on the sum of 3 skinfolds (triceps, subscapular, and supraspinal) corrected for height
  • Mesomorphy (relative musculoskeletal robustness):
    • Strongly built, muscular arms/legs, little body fat
    • Calculated based on height, breadth of humerus and femur, girth of bicep (flexed and relaxed), skin fold measure for body fat
  • Ectomorphy (relative linearity or slenderness):
    • Tall, thin, low body fat
    • Calculated based on height, weight, and height/weight ratio

Puberty

  • Puberty: period of time in which secondary characteristics are developed
  • Characterized by:
    • Accelerated body growth
    • Rapid growth of gonads
    • Increased production of gonadal hormones
    • Secondary sex characteristics (female breast development and pubic hair)
    • Ability to reproduce
  • Increased GnRH from hypothalamus during puberty = increase in LH and FSH from anterior pituitary = targets gonads to promote growth and function and stimulate production of gametes

Hormones

  • Estrogen:
    • Growth of ovaries and secondary sex characteristics
    • Stimulates GH = increase height and pelvic widening
    • Suppresses LH and FSH
  • Progesterone:
    • Prepares uterus for fertilization
    • Suppresses LH and FSH
  • Inhibin:
    • Suppresses LH and FSH
  • Testosterone:
    • Sperm cell production and maturity of male secondary sex characteristics
    • Hypertrophy of larynx and change in voice
    • Increase metabolism
    • Increase erythropoietin production (RBC)

Menstrual Cycle

  • Ovarian cycle (events in the ovaries) prior to ovulation:
    • GnRH secretion = increase FSH = stimulates granulosa cells
    • LH = stimulates theca interna cells
    • Follicle growth and maturation
    • Increase estrogen levels prior to ovulation
    • Maturing follicles secrete inhibin = decrease FSH
  • Ovulation:
    • LH initiates ovulation + generation of corpus luteum
    • Secondary oocyte is released into fallopian tubes with 2 fates
  • After ovulation:
    • Decreased estrogen
    • Corpus luteum secretes increased progesterone
    • Progesterone and estrogen = negative feedback on GnRH = decrease LH and FSH
  • Menstrual cycle:
    • Typically 28 days with 2 phases
    • Follicular phase (day 1-14)
    • Luteal phase (day 14+)

Fertilization and Implantation

  • Fertilization:
    • Step 1: Sperm cells pass through corona radiata
    • Step 2: Sperm cells come into contact with zone pellucida
    • Step 3: 1 sperm cell enters into oocyte
    • Step 4: Male pronucleus and female pronucleus merge to form 1 single nucleus
  • Cell division in distal uterine tubes continues after fertilization
    • Day 1: 2 cells
    • Day 2: 4 cells
    • Day 5: Morula with 12 or more cells
    • Day 6/7: Blastocyst with fluid-filled cavity
  • Implantation:
    • The burrowing of blastocyst into uterine wall

Placenta

  • Anatomy:
    • Maternal side: the side of the mother's uterus
    • Fetal side: the side that interfaces with the uterus
    • Umbilical cord: connects the fetus to the placenta
    • Umbilical arteries carry deoxygenated blood and waste products from the fetus to the placenta
    • Umbilical veins carry oxygenated blood and nutrients from the placenta to the fetus
  • Function:
    • Acts as a barrier between maternal and fetal circulations
    • Allows for gas exchange, exchange of nutrients and waste products

Hormonal Changes During Pregnancy

  • First trimester:
    • Placenta secretes high amounts of hCG
    • Ovaries secrete progesterone and estrogen
  • Second trimester:
    • Placenta secretes hCG, progesterone, and estrogen
    • Ovaries secrete small amounts of progesterone and estrogen
  • Third trimester:
    • Placenta secretes small amount of hCG and high amounts of progesterone and estrogen

Changes During Pregnancy

  • Cardiovascular changes:
    • Blood volume increases
    • HR increases
    • Stroke volume increases
    • Cardiac output increases
  • Respiratory changes:
    • Tidal volume increases
    • Minute volume increases
  • Renal changes:
    • Increased plasma volume causes kidneys to enlarge and increase in renal blood flow
    • GFR increases
  • Thermoregulatory changes:
    • Increased metabolic rate causes increased heat production
    • Heat is lost by increased ventilation and increased skin blood flow

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