Functions and Composition of Blood

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What is the main function of erythrocytes?

Contribute to gas transport

What is the normal hemoglobin range for females?

12-16 g/100ml

Which component of hemoglobin is responsible for binding with oxygen?

Heme pigment

What effect would low iron levels have on a patient?

An increase in fatigue

What is the role of erythropoietin (EPO) in the body?

Stimulate red blood cell production

What is the composition of globin in hemoglobin?

Two alpha and two beta chains

What triggers the synthesis of EPO?

Decreased availability of O2

Where is 65% of iron found in the body?

Hemoglobin

What are the symptoms of anemia?

Fatigue, pallor, dyspnea, and chills

What is the life span of RBCs?

100-120 days

What is the cause of secondary polycythemia?

High altitude or increased EPO production

What is the function of vitamin B12 and folic acid in RBC production?

To synthesize DNA for developing RBCs

What is the main function of EPO?

Stimulate red bone marrow

What are the consequences of polycythemia vera?

Excess RBCs and increased blood viscosity

What happens when HIF accumulates in the body?

Triggers synthesis of EPO

What is the potential outcome of an overdose of the hormone erythropoietin?

The blood viscosity increases to levels that may induce heart attacks or strokes.

What is the primary function of vitamin B12 and folic acid in red blood cell production?

Facilitate DNA synthesis for rapidly dividing cells such as developing RBCs.

Which condition is characterized by an abnormal excess of red blood cells and increases blood viscosity?

Polycythemia vera

What is the consequence of secondary polycythemia caused by low oxygen levels or increased EPO production?

Abnormal excess of RBCs and increased blood viscosity.

What is the role of HIF (hypoxia-inducible factor) in response to decreased availability of oxygen?

It accumulates and triggers the synthesis of EPO (erythropoietin).

What is the composition of hemoglobin?

Two alpha and two beta chains

What is the role of spectrin in erythrocytes?

Maintains the biconcave disc shape

What is the function of erythropoietin (EPO)?

Stimulates the production of red blood cells

What triggers the release of erythropoietin (EPO) from the kidneys?

Low blood oxygen levels

What is the primary function of erythrocytes?

Carrying respiratory gases in the blood

Test your knowledge of the functions and composition of blood, including its role in transporting, regulating, and protecting the body. Learn about the different types of blood cells and their functions, as well as the composition and function of hemoglobin.

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