5 Questions
What is the key difference between solubility and dissolution?
Solubility is an intrinsic material property, while dissolution is an extrinsic material property affected by physical and chemical properties.
What defines a saturated solution?
The solute is in equilibrium with the solid phase.
What characterizes a solution according to the text?
A mono-molecular dispersion of a drug in a liquid, optically clear, and with no visible particles.
What does osmolarity measure?
The concentration of osmotically active particles per liter of solution.
What does tonicity refer to?
The ability of a solution to cause a cell to shrink or swell due to osmotic forces.
Study Notes
Solubility and Dissolution
- Solubility is the maximum amount of a substance that can dissolve in a given amount of solvent, whereas dissolution is the process of a substance dissolving in a solvent.
Saturated Solution
- A saturated solution is a solution that contains the maximum amount of dissolved substance, beyond which no more can be dissolved.
Characteristics of a Solution
- A solution is a homogeneous mixture of two or more substances, where the particles of the substances are evenly distributed throughout the mixture.
Osmolarity
- Osmolarity measures the concentration of solutes in a solution, expressed in units of osmoles per liter (osm/L).
Tonicity
- Tonicity refers to the ability of a solution to cause water to move into or out of a cell, with hypertonic solutions causing water to leave the cell, hypotonic solutions causing water to enter the cell, and isotonic solutions having no net effect on water movement.
Learn about the formulation of safe and effective medicines in pharmacy, covering the types of solution products, physico-chemical issues, and formulation strategies. Understand key terms such as solubility and its relevance in pharmaceutical solutions.
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