Food Sensitivity and Oral Tolerance Concepts Quiz

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What is the key event in food allergy?

Production of excessive nutrients in response to allergens.

Recognition of the food by the immune system components. (correct)

Activation of the oral tolerance mechanisms.

Increased inflammation due to the food's properties.

What is an epitope in the context of food allergy?

An inflammatory mediator that causes body tissue reactions.

A component of the immune molecule.

The actual section of the allergen that connects with the immune molecule. (correct)

A carbohydrate chain attached to a protein.

How are adverse reactions in food allergy caused?

By the food protein coming in contact with the immune system.

By the food itself containing toxicants.

By the immune system overreacting to hapten molecules.

By the individual's unique response to the food. (correct)

What is described by the term food sensitivity-related illness?

Individuals developing sensitivities to toxicants leading to reactions to different substances. Signup and view all the answers

What allows an individual to eat food without any ill effects in the context of the text?

Oral tolerance mechanisms. Signup and view all the answers

What is the common characteristic of the allergens that cause food allergies?

Protein or glycoprotein nature. Signup and view all the answers

What is the role of dysbiosis in allergy development?

Contributes to increased intestinal permeability Signup and view all the answers

Which factor is mentioned as a cause of disruptions in microbiota?

Cesarean delivery Signup and view all the answers

What is the largest mass of lymphoid tissue in the body?

Gut-associated lymphoid tissue (GALT) Signup and view all the answers

Which condition is NOT associated with increased gut permeability and risk of food allergy development?

Consuming probiotics Signup and view all the answers

Where do B-cells primarily originate from?

Bone marrow Signup and view all the answers

What is the main function of T-cells?

Command and control of the immune system Signup and view all the answers

What is the second phase in the pathophysiology of the allergic response?

Allergen Sensitization Signup and view all the answers

What is the key factor associated with loss of oral tolerance that leads to allergen sensitization?

Immune system recognition of food molecules as foreign Signup and view all the answers

Which cells are involved in the sensitization phase of the allergic response?

Dendritic and epithelial cells Signup and view all the answers

What happens during the reactivity phase to allergens in the allergic response?

Release of inflammatory mediators Signup and view all the answers

How does the immune response change in the sensitization phase compared to the breakdown of oral tolerance phase?

Th-2 response involvement Signup and view all the answers

What characterizes the first phase in the pathophysiology of the allergic response?

Loss of oral tolerance Signup and view all the answers

What is the purpose of listing food dyes separately on a food label?

To make it easier for consumers to spot food colors or dyes Signup and view all the answers

What is the main idea behind the Top 8 Challenge mentioned in the text?

To identify 8 common food allergens for elimination Signup and view all the answers

What foods are typically included during the elimination phase of the oligoantigenic diet?

Rice, turkey, lettuce, pears, water Signup and view all the answers

What is the duration of the elimination phase in the oligoantigenic diet?

Two to five weeks Signup and view all the answers

What is the purpose of the oligoantigenic diet's elimination phase?

To exclude specific food items completely Signup and view all the answers

Which type of dysbiosis is defined as the overgrowth of potentially pathogenic bacteria within the gut?

Overgrowth of potentially pathogenic bacteria Signup and view all the answers

What is oral tolerance?

Active process of immune unresponsiveness to ingested antigens Signup and view all the answers

What is the function of an epitope in relation to allergens?

A component that engages with the immune molecule Signup and view all the answers

What is the significance of sensitization in IgE-mediated food allergy?

Not adequate on its own to classify food allergy Signup and view all the answers

Which of the following mechanisms is NOT mentioned as a potential cause of food allergy in the text?

Loss of overall bacterial diversity Signup and view all the answers

What does dysbiosis refer to in the context of the passage?