Fluconazole Flashcards

Questions and Answers

What is the generic name of the drug?

Fluconazole

What is the trade name of Fluconazole?

Diflucan

What classification does Fluconazole fall under?

Azole Antifungal

What are the available forms of Fluconazole?

50mg, 100mg, 150mg, 200mg tablets; 10mg/ml, 40mg/ml suspension; 2mg/ml injection Signup and view all the answers

What is the primary action of Fluconazole?

Interferes with formation of ergosterol in fungal cell membranes, leading to cell death Signup and view all the answers

What are the common uses of Fluconazole?

Cryptococcal meningitis and oropharyngeal and systemic candidiasis, vaginal candidiasis Signup and view all the answers

What are the contraindications for Fluconazole?

Hypersensitivity to fluconazole or other azole antifungals; lactation Signup and view all the answers

What are some common adverse effects of Fluconazole?

Headache, nausea, vomiting, abdominal pain, diarrhea, rash Signup and view all the answers

What are important nursing implications when administering Fluconazole?

Monitor for allergy response and lab values; inform prescriber of all medications Signup and view all the answers

Study Notes

Fluconazole Overview

Generic Name: Fluconazole
Trade Name: Diflucan
Classification: Azole Antifungal

Formulations Available

Tablets: 50mg, 100mg, 150mg, 200mg
Suspension: 10mg/ml, 40mg/ml
Injection: 2mg/ml

Mechanism of Action

Interferes with ergosterol formation, essential for fungal cell membranes.
Leads to fungal cell death by disrupting membrane function.

Therapeutic Uses

Treats cryptococcal meningitis, often in AIDS patients.
Effective against oropharyngeal and systemic candidiasis.
Used for vaginal candidiasis.

Contraindications

Not suitable for individuals with hypersensitivity to fluconazole or other azole antifungals.
Contraindicated during lactation.

Adverse Effects

Common side effects include headache, nausea, vomiting, and abdominal pain.
Potential for diarrhea and rash.
Increased AST levels in patients with cryptococcal meningitis and AIDS.

Nursing Implications

Monitor for allergic reactions, especially in patients with allergies to other antifungals.
Regularly check BUN, serum creatinine, and liver function tests due to possible hepatotoxicity.
Elevated lab values may include ALT, AST, alkaline phosphatase, and bilirubin.
Educate patients, especially those with diabetes, to monitor glycemic control.
Advise patients to inform healthcare providers of all medications being taken.

Description

Test your knowledge with these flashcards on Fluconazole. Covering its generic and trade names, classifications, availability, and action mechanisms, this quiz is perfect for students and professionals in medicine and pharmacy. Boost your understanding of this important antifungal medication.