Finasteride

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Questions and Answers

What are the two brand names under which Finasteride is sold?

Proscar and Propecia

What is the primary medical condition that Finasteride is used to treat in men?

Pattern hair loss and benign prostatic hyperplasia (BPH)

What is the mechanism of action of Finasteride?

It is a 5α-reductase inhibitor, decreasing the production of dihydrotestosterone (DHT) by about 70%

What are some of the neurosteroids whose production is inhibited by Finasteride?

<p>Allopregnanolone, androstanediol, and THDOC</p> Signup and view all the answers

What are some of the adverse effects that some men may experience from taking Finasteride?

<p>Sexual dysfunction, depression, and breast enlargement</p> Signup and view all the answers

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Study Notes

Finasteride Medication

  • Sold under brand names Proscar and Propecia, among others
  • Used to treat:
    • Pattern hair loss in men
    • Benign prostatic hyperplasia (BPH) in men
    • Excessive hair growth in women

Mechanism of Action

  • 5α-reductase inhibitor
  • Antiandrogen
  • Decreases production of dihydrotestosterone (DHT) by approximately 70%
  • Inhibits production of neurosteroids, including:
    • Allopregnanolone
    • Androstanediol
    • THDOC

Adverse Effects

  • Rare, but may include:
    • Sexual dysfunction
    • Depression
    • Breast enlargement
  • In some cases, sexual dysfunction may persist after stopping medication
  • May mask early symptoms of certain prostate cancer forms

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