Factors Contributing to Inflammatory Bowel Disease (IBD)
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Questions and Answers

Which statement about genetic factors in inflammatory bowel disease (IBD) is correct?

  • Genetic predisposition contributes to the development of IBD. (correct)
  • Familial IBD is less common among relatives of patients with IBD than in the general population.
  • Genetic factors have no influence on the development of IBD.
  • Genetic factors play a more prominent role in ulcerative colitis than in Crohn's disease.

    • Which of the following statements about familial IBD is true?

  • Familial IBD is equally common among relatives of patients with IBD and in the general population.
  • Familial IBD is less common among relatives of patients with IBD than in the general population.
  • Familial IBD is more common among relatives of patients with IBD than in the general population. (correct)
  • Familial IBD has no association with the occurrence of IBD in relatives.

    • In the context of Crohn's disease and ulcerative colitis, which statement about genetic factors is correct?

  • Genetic factors play an equal role in both Crohn's disease and ulcerative colitis.
  • Genetic factors play a more prominent role in Crohn's disease than in ulcerative colitis. (correct)
  • Genetic factors do not play a role in either Crohn's disease or ulcerative colitis.
  • Genetic factors play a more prominent role in ulcerative colitis than in Crohn's disease.

    • Which of the following genes is associated with susceptibility to inflammatory bowel disease (IBD)?

    <p>NOD2/CARD15 gene</p> Signup and view all the answers

    What is the primary function of the NOD2/CARD15 protein?

    <p>Prevents the entry of microbes into the intestinal wall and regulates innate immune responses.</p> Signup and view all the answers

    What is the consequence of a defective NOD2/CARD15 protein?

    <p>It allows the entry of luminal microbes into the intestinal wall and stimulates inflammatory reactions.</p> Signup and view all the answers

    Which statement about genetic factors in Crohn's disease is correct?

    <p>Crohn's disease has a strong genetic component, with family history being an important risk factor.</p> Signup and view all the answers

    In Crohn's disease, which of the following statements about genetic susceptibility is true?

    <p>Multiple susceptibility genes interact with environmental factors to contribute to the disease.</p> Signup and view all the answers

    Which of the following statements regarding familial Crohn's disease is accurate?

    <p>Individuals with a family history of Crohn's disease have an increased risk of developing the disease.</p> Signup and view all the answers

    Which of the following statements about genetic factors in inflammatory bowel diseases (IBD) is true?

    <p>Genetic factors contribute to the development of both Crohn's disease and ulcerative colitis, but different genes are involved.</p> Signup and view all the answers

    Which of the following statements about the genetic basis of Crohn's disease is correct?

    <p>Crohn's disease is caused by a combination of genetic and environmental factors.</p> Signup and view all the answers

    Which of the following statements regarding genetic factors in inflammatory bowel diseases (IBD) is accurate?

    <p>Genetic factors contribute to the development of IBD, but different genes are involved in Crohn's disease and ulcerative colitis.</p> Signup and view all the answers

    What is the primary cause of peptic ulcers according to the passage?

    <p>Infection with H. pylori bacteria</p> Signup and view all the answers

    How do H. pylori bacteria contribute to the development of peptic ulcers?

    <p>They secrete enzymes that disrupt the mucosal barrier</p> Signup and view all the answers

    According to the passage, which of the following is not a factor contributing to the pathogenesis of peptic ulcers?

    <p>Genetic predisposition</p> Signup and view all the answers

    How do neuroendocrine factors contribute to the development of peptic ulcers?

    <p>They disrupt the normal regulation of gastric acid secretion</p> Signup and view all the answers

    What is the proposed mechanism by which the gastric acid of ulcer patients can lead to mucosal ulcerations?

    <p>The acid causes a back-diffusion of hydrogen ions, damaging the glands</p> Signup and view all the answers

    Which of the following factors is not mentioned in the passage as contributing to the pathogenesis of peptic ulcers?

    <p>Genetic predisposition</p> Signup and view all the answers

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