Podcast
Questions and Answers
What is a common issue that might arise in a hemophilia A patient if a factor assay does not match expected levels after a therapeutic infusion of factor concentrate?
What is a common issue that might arise in a hemophilia A patient if a factor assay does not match expected levels after a therapeutic infusion of factor concentrate?
- Presence of spontaneous inhibitors (correct)
- Decreased white blood cell count
- Excess red blood cell production
- Increased platelet count
What is the purpose of the Whole Blood Clot Lysis Time test?
What is the purpose of the Whole Blood Clot Lysis Time test?
- Detecting increased fibrinolysis (correct)
- Measuring red blood cell count
- Determining white blood cell activity
- Assessing platelet function
What happens when a clot in the bloodstream detaches and circulates, potentially leading to obstructions in organs?
What happens when a clot in the bloodstream detaches and circulates, potentially leading to obstructions in organs?
- Enhanced clot dissolution process
- Decreased risk of clot-related issues
- Formation of aneurysm in the lungs
- Increased risk of pulmonary embolism (correct)
Which antibodies are responsible for neutralizing the function of a specific factor in hemophilia patients?
Which antibodies are responsible for neutralizing the function of a specific factor in hemophilia patients?
In the context of fibrinolysis, what is the role of excess systemic fibrinolysis?
In the context of fibrinolysis, what is the role of excess systemic fibrinolysis?
Which test is specifically used to detect high increases in fibrinolytic activity?
Which test is specifically used to detect high increases in fibrinolytic activity?
What is the primary function of fibrinolysis?
What is the primary function of fibrinolysis?
Why do the results of more concentrated dilutions (1:10, 1:20) tend to be lower in the presence of inhibitors like Lupus inhibitors or heparin?
Why do the results of more concentrated dilutions (1:10, 1:20) tend to be lower in the presence of inhibitors like Lupus inhibitors or heparin?
In the provided table, which dilution resulted in an activity percentage of 6.3%?
In the provided table, which dilution resulted in an activity percentage of 6.3%?
What happens when there is hyperactivity of fibrinolysis?
What happens when there is hyperactivity of fibrinolysis?
What is the significance of performing coagulation tests on a timerometer?
What is the significance of performing coagulation tests on a timerometer?
Which tube from the table had a dilution resulting in 25% activity?
Which tube from the table had a dilution resulting in 25% activity?
What is the next step if no correction is seen in mixing studies for a patient with factor deficiency?
What is the next step if no correction is seen in mixing studies for a patient with factor deficiency?
Which of the following is used to determine the plasma concentration of factors II, V, VII, and X?
Which of the following is used to determine the plasma concentration of factors II, V, VII, and X?
What is the normal range of activity for factors II, V, VII, and X in plasma?
What is the normal range of activity for factors II, V, VII, and X in plasma?
In factor V deficiency, what is used as a reference plasma for testing?
In factor V deficiency, what is used as a reference plasma for testing?
What does the amount of correction by patient's plasma in a prothrombin time test correlate with?
What does the amount of correction by patient's plasma in a prothrombin time test correlate with?
What should be checked if specific factor assays reveal low concentration of a particular factor?
What should be checked if specific factor assays reveal low concentration of a particular factor?
What is the principle behind the Ethanol Gelation Test?
What is the principle behind the Ethanol Gelation Test?
What is the significance of a positive result in the Latex D-Dimer Assay?
What is the significance of a positive result in the Latex D-Dimer Assay?
Which of the following conditions is NOT associated with a decreased level of plasminogen?
Which of the following conditions is NOT associated with a decreased level of plasminogen?
What is the purpose of the Plasminogen Assay?
What is the purpose of the Plasminogen Assay?
What is the reference interval for the Prothrombin Time (PT) mentioned in the text?
What is the reference interval for the Prothrombin Time (PT) mentioned in the text?
What is the significance of a positive result in the Latex Fibrin Degradation Product (FDP) Assay?
What is the significance of a positive result in the Latex Fibrin Degradation Product (FDP) Assay?
What is the substrate that the enzyme peroxidase acts on in the presence of hydrogen peroxide?
What is the substrate that the enzyme peroxidase acts on in the presence of hydrogen peroxide?
What is the proportion of total protein S antigen in the plasma that is normally bound to C4b?
What is the proportion of total protein S antigen in the plasma that is normally bound to C4b?
What is the role of the free protein S in the plasma?
What is the role of the free protein S in the plasma?
What happens to the protein S bound to C4b BP?
What happens to the protein S bound to C4b BP?
Which of the following is not a cause of acquired deficiency of protein S?
Which of the following is not a cause of acquired deficiency of protein S?
