Clot Dissolution and FACTOR XIII Deficiency

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18 Questions

Which disease is associated with acquired deficiency of FACTOR XIII?

Henoch-Schonlein purpura

What is the sensitivity of clot dissolution in 5M urea or monochloroacetic acid?

30%

Which type of deficiency has low or absent plasma fibrinogen antigen levels?

Type III FACTOR XIII deficiency

What is the common cause of acquired deficiency of FACTOR XIII?

Isoniazid treatment for tuberculosis

What is the most appropriate replacement therapy for most patients with FXIII deficiency due to its long half-life?

Fresh frozen plasma

Which type of deficiency has disproportionately low function activity despite normal or reduced antigen levels?

Quantitative fibrinogen deficiency

Which type of hemostasis disorder is characterized by a delayed onset of bleeding after trauma or surgery?

Secondary hemostasis

In which of the following sites is bleeding less common in secondary hemostasis disorders?

Joints and muscles

Which test estimates fibrinogen concentration by measuring the time taken for plasma to clot upon addition of thrombin?

Thrombin time

Which factor deficiency is associated with factor XIII deficiency?

Factor V deficiency

What does thrombin attack directly to convert it to fibrin?

Fibrinogen

Which test is used for estimating the fibrinogen concentration in a patient?

Thrombin time

Which factor deficiency is associated with amyloidosis?

Factor X

In what percent range is considered mild hemophilia?

5% to 20%

Which synthetic analog of ADH increases plasma Factor VIII levels?

DDAVP

Which factor deficiency is the most common rare inherited coagulation disorder?

Factor XI

What is the factor deficiency often associated with primary amyloidosis?

Factor X

For what disorder is Tissue Factor Deficiency not observed?

Hemophilia

Test your knowledge on clot dissolution in 5M urea or monochloroacetic acid and the implications of FACTOR XIII deficiency. Explore acquired deficiency of FACTOR XIII in diseases like HENOCH - SCHONLEIN PURPURA, colitis, gastritis, and leukemia.

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