18 Questions
Which disease is associated with acquired deficiency of FACTOR XIII?
Henoch-Schonlein purpura
What is the sensitivity of clot dissolution in 5M urea or monochloroacetic acid?
30%
Which type of deficiency has low or absent plasma fibrinogen antigen levels?
Type III FACTOR XIII deficiency
What is the common cause of acquired deficiency of FACTOR XIII?
Isoniazid treatment for tuberculosis
What is the most appropriate replacement therapy for most patients with FXIII deficiency due to its long half-life?
Fresh frozen plasma
Which type of deficiency has disproportionately low function activity despite normal or reduced antigen levels?
Quantitative fibrinogen deficiency
Which type of hemostasis disorder is characterized by a delayed onset of bleeding after trauma or surgery?
Secondary hemostasis
In which of the following sites is bleeding less common in secondary hemostasis disorders?
Joints and muscles
Which test estimates fibrinogen concentration by measuring the time taken for plasma to clot upon addition of thrombin?
Thrombin time
Which factor deficiency is associated with factor XIII deficiency?
Factor V deficiency
What does thrombin attack directly to convert it to fibrin?
Fibrinogen
Which test is used for estimating the fibrinogen concentration in a patient?
Thrombin time
Which factor deficiency is associated with amyloidosis?
Factor X
In what percent range is considered mild hemophilia?
5% to 20%
Which synthetic analog of ADH increases plasma Factor VIII levels?
DDAVP
Which factor deficiency is the most common rare inherited coagulation disorder?
Factor XI
What is the factor deficiency often associated with primary amyloidosis?
Factor X
For what disorder is Tissue Factor Deficiency not observed?
Hemophilia
Test your knowledge on clot dissolution in 5M urea or monochloroacetic acid and the implications of FACTOR XIII deficiency. Explore acquired deficiency of FACTOR XIII in diseases like HENOCH - SCHONLEIN PURPURA, colitis, gastritis, and leukemia.
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