Exertional Heat Stroke Quiz

Which organ is most affected in exertional heat stroke?

Which condition can exertional heat stroke trigger?

What happens to tissue oxygen demand and metabolic rate in exertional heat stroke?

What can severe hyperthermia in exertional heat stroke lead to?

What can the release of procoagulant proteins in exertional heat stroke trigger?

Which coagulation cascade is excessively activated in DIC?

What is generated in DIC as a result of the excessive activation of the coagulation cascade?

What happens to plasminogen in DIC?

Which laboratory finding is characteristic of acute DIC?

What is a common clinical manifestation of acute DIC?

What is the underlying cause of thrombocytopenia in acute DIC?

Which factor do direct factor Xa inhibitors block to reduce conversion of prothrombin to thrombin?

How are direct factor Xa inhibitors administered?

Do direct factor Xa inhibitors require drug level monitoring?

What converts plasminogen to plasmin?

What is the primary use of tissue plasminogen activator?

What is the role of tissue plasminogen activator in fibrinolysis?

Which clotting factors are prevented from gamma carboxylation by the action of warfarin?

How long does it take for the therapeutic effect of warfarin to occur?

What is the primary site of action of warfarin?

How long does it take for the therapeutic effect of warfarin to occur?

What is the mechanism of action of warfarin?

Which patient population is at increased risk for developing lower extremity deep venous thrombosis (DVT)?

When is DVT prophylaxis usually initiated in patients undergoing certain orthopedic procedures such as hip and knee replacement?

Which type of heparin does not require laboratory monitoring when given therapeutically?

What is the primary target of LMWH when it activates antithrombin III (AT III)?

What is the mechanism of action of unfractionated heparin when it binds to antithrombin III (AT III)?

Which medication is useful for inhibiting ADP-mediated platelet aggregation?

What is the primary use of clopidogrel and ticlopidine?

Which factor does low-molecular-weight heparin (LMWH) primarily act on?

What is the main function of antithrombin III (AT III) when activated by Enoxaparin?

How does Enoxaparin differ from heparin in terms of molecular weight?

Which fat-soluble vitamin deficiency is most likely causing the patient's symptoms?

What is the primary cause of increased risk of vitamin K deficiency in patients with CF?

Which of the following symptoms is NOT consistent with EARLY vitamin K deficiency in patients with CF?

Which of the following statements about Andexanet alfa is correct?

Which of the following is a use for Andexanet alfa?

Which of the following medications is commonly reversed by Andexanet alfa?

Which enzyme is specifically targeted by direct oral anticoagulants?

What is the primary target of heparin when it activates antithrombin III (AT III)?

What is the effect of heparin on thrombin time/partial thromboplastin time?

Which laboratory finding is commonly seen in patients with antiphospholipid antibody syndrome?

What is a characteristic feature of antiphospholipid antibody syndrome?

What can antiphospholipid antibodies in systemic lupus erythematosus cause?

Which laboratory finding is commonly seen in patients with disseminated intravascular coagulation (DIC)?

What is the primary cause of disseminated intravascular coagulation (DIC)?

Which of the following is a characteristic sign of disseminated intravascular coagulation (DIC)?

Which of the following medications is a potent enhancer of the cytochrome P-450 pathway and can decrease the efficacy of warfarin?

Which of the following medications can inhibit warfarin metabolism and increase the risk of bleeding?

Which of the following medications does NOT affect the metabolism or efficacy of warfarin?

Which of the following is a manifestation of vitamin C deficiency?

What is the main role of vitamin C in the body?

Which of the following is/are characteristics of vitamin C deficiency?

Which of the following is a symptom of scurvy?

Which of the following is a hemorrhagic complication of scurvy?

Which vitamin deficiency can cause perifollicular hyperkeratosis?

Which vitamin K-dependent coagulation factor has the shortest half-life?

What does failure of prothrombin time to correct with vitamin K supplementation in liver disease indicate?

What is the most common cause of factor VII deficiency?

Which condition can lead to high-output heart failure in patients with severe cirrhosis?

What is the primary cause of high-output heart failure in severe cirrhosis?

Which of the following is a potential complication of starting patients on warfarin?

What factor can further exacerbate the hypercoagulability seen in patients started on warfarin?

What is the primary cause of thrombotic occlusion in patients started on warfarin?

Which of the following is a characteristic of acute disseminated intravascular coagulation (DIC)?

What is the most common cause of bleeding complications in acute disseminated intravascular coagulation (DIC)?

Which of the following is a consequence of widespread formation of microvascular thrombi in acute disseminated intravascular coagulation (DIC)?

Which type of anticoagulant is used to treat heparin-induced thrombocytopenia (HIT)?

What should be avoided in patients with heparin-induced thrombocytopenia (HIT)?

What is the primary treatment for heparin-induced thrombocytopenia (HIT)?