MODULE 1_UNIT 1
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Questions and Answers

What is the principal pigment of bile?

  • Water
  • Heme
  • Bilirubin (correct)
  • Cholesterol
  • How is bilirubin transported to the liver?

  • Through active transport
  • Through receptor-mediated endocytosis (correct)
  • Through simple endocytosis
  • Through diffusion
  • Where does the breakdown of RBCs occur?

  • Spleen (correct)
  • Liver
  • Bone marrow
  • Kidneys
  • What is the iron-binding component in hemoglobin?

    <p>Heme</p> Signup and view all the answers

    What enzyme reduces biliverdin to bilirubin?

    <p>Biliverdin reductase</p> Signup and view all the answers

    What should be the normal levels of total bilirubin in the serum of a healthy adult?

    <p>0.2-1.0 mg/dL</p> Signup and view all the answers

    What is the approximate amount of blood that passes through the liver per minute?

    <p>1,500 mL</p> Signup and view all the answers

    Which two blood supplies merge into the hepatic sinusoid?

    <p>Hepatic artery, portal vein</p> Signup and view all the answers

    What is the upper limit normal for total bilirubin

    <p>1.0-1.5 mg/dL</p> Signup and view all the answers

    Which cells line the hepatic sinusoid?

    <p>Kupffer cells</p> Signup and view all the answers

    How is the liver divided by the falciform ligament?

    <p>Into right and left lobes</p> Signup and view all the answers

    Which type of cells in the liver are derived from monocytes?

    <p>Kupffer cells</p> Signup and view all the answers

    What is the main function of stellate cells in the liver?

    <p>Regulate liver blood flow</p> Signup and view all the answers

    Which cells in the liver are responsible for clearance of antigen-antibody complexes in venous blood?

    <p>Kupffer cells</p> Signup and view all the answers

    What is the composition of portal triads in the liver?

    <p>Hepatic artery, portal vein, bile duct</p> Signup and view all the answers

    Which cells make up approximately 80% of the liver volume and perform most liver functions?

    <p>Hepatocytes</p> Signup and view all the answers

    What is the role of oval cells in the liver?

    <p>Involved in regeneration after injury</p> Signup and view all the answers

    What do Kupffer cells contain that helps in phagocytosis and breakdown of foreign substances?

    <p>Lysosomes with hydrolytic enzymes</p> Signup and view all the answers

    Where do the intrahepatic ducts drain the excretory products of the cell?

    <p>Into the common bile duct</p> Signup and view all the answers

    What is the function of the hepatic artery in the liver?

    <p>Provides oxygen-rich blood to the liver</p> Signup and view all the answers

    Which blood vessel supplies approximately 75% of the total blood supply to the liver?

    <p>Portal vein</p> Signup and view all the answers

    What is the final structure formed by the merging of right and left hepatic ducts?

    <p>Common bile duct</p> Signup and view all the answers

    In the excretory system of the liver, where does the cystic duct join to form a larger structure?

    <p>Common bile duct</p> Signup and view all the answers

    Which form of bilirubin can cross the blood-brain barrier?

    <p>Unconjugated bilirubin</p> Signup and view all the answers

    Which form of bilirubin is water-soluble and can appear in urine?

    <p>Direct bilirubin</p> Signup and view all the answers

    Which fraction of bilirubin has a half-life of about 17-20 days?

    <p>Delta bilirubin</p> Signup and view all the answers

    Which form of bilirubin can be transformed to the cis form upon exposure to light?

    <p>Indirect bilirubin</p> Signup and view all the answers

    Which form of bilirubin requires an accelerator to react with diazo reagent?

    <p>Indirect bilirubin</p> Signup and view all the answers

    Which form of bilirubin is bound to albumin and not readily filtered by the glomerulus?

    <p>Delta bilirubin</p> Signup and view all the answers

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