Podcast
Questions and Answers
Which statistical procedure is most appropriate for comparing the average scores of two different treatment groups on a continuous outcome measure?
Which statistical procedure is most appropriate for comparing the average scores of two different treatment groups on a continuous outcome measure?
A researcher wants to determine if there is a significant difference in the proportion of patients who experience a positive outcome after receiving either a new medication or a standard treatment. Which statistical procedure is most appropriate for this analysis?
A researcher wants to determine if there is a significant difference in the proportion of patients who experience a positive outcome after receiving either a new medication or a standard treatment. Which statistical procedure is most appropriate for this analysis?
In the context of research, what does "intention-to-treat" analysis mean?
In the context of research, what does "intention-to-treat" analysis mean?
What does "effect size" in research refer to?
What does "effect size" in research refer to?
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A researcher finds a large effect size (Cohen's d > 0.8) in their study. What can be concluded based on this finding?
A researcher finds a large effect size (Cohen's d > 0.8) in their study. What can be concluded based on this finding?
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What is the primary purpose of "Number Needed to Treat" (NNT)?
What is the primary purpose of "Number Needed to Treat" (NNT)?
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Which of the following is NOT considered a barrier to evidence-based practice (EBP)?
Which of the following is NOT considered a barrier to evidence-based practice (EBP)?
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Which of the following BEST describes the concept of "shared informed decision-making" in therapy?
Which of the following BEST describes the concept of "shared informed decision-making" in therapy?
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What is the primary goal of Evidence-Based Practice (EBP)?
What is the primary goal of Evidence-Based Practice (EBP)?
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Which of the following best defines 'Clinical Expertise' in the context of EBP?
Which of the following best defines 'Clinical Expertise' in the context of EBP?
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Which step comes immediately after identifying the need for information in the EBP process?
Which step comes immediately after identifying the need for information in the EBP process?
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What type of research question seeks to provide a summary of specific features of the world?
What type of research question seeks to provide a summary of specific features of the world?
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How does EBP benefit patient treatment?
How does EBP benefit patient treatment?
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Which of the following is NOT considered a pillar of Evidence-Based Practice?
Which of the following is NOT considered a pillar of Evidence-Based Practice?
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What is an essential component of a predictive research question?
What is an essential component of a predictive research question?
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What does the 'Evaluate' step of EBP involve?
What does the 'Evaluate' step of EBP involve?
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What is the main distinction between prediction and causation in research?
What is the main distinction between prediction and causation in research?
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Which study design is primarily used to establish causality?
Which study design is primarily used to establish causality?
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What is the purpose of randomization in research?
What is the purpose of randomization in research?
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What does a narrow confidence interval suggest about a study's findings?
What does a narrow confidence interval suggest about a study's findings?
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What is an example of a surrogate outcome in a clinical study?
What is an example of a surrogate outcome in a clinical study?
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Which type of error occurs when a statistically significant difference is incorrectly concluded to exist?
Which type of error occurs when a statistically significant difference is incorrectly concluded to exist?
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What does the term 'blinding' refer to in research studies?
What does the term 'blinding' refer to in research studies?
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Which of the following is NOT a measure of variability in statistics?
Which of the following is NOT a measure of variability in statistics?
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What does the 'alpha level' typically represent in hypothesis testing?
What does the 'alpha level' typically represent in hypothesis testing?
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In a randomized controlled trial, what is the sham group used for?
In a randomized controlled trial, what is the sham group used for?
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Which of the following is considered a type of inferential statistic?
Which of the following is considered a type of inferential statistic?
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What is the main concern regarding conflicts of interest in research studies?
What is the main concern regarding conflicts of interest in research studies?
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What type of reliability assesses the consistency of measurements by the same therapist?
What type of reliability assesses the consistency of measurements by the same therapist?
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Flashcards
Evidence-Based Practice (EBP)
Evidence-Based Practice (EBP)
Integration of research evidence, clinical expertise, and patient values in care.
Goals of EBP
Goals of EBP
To inform patient care with the best evidence and optimize therapy benefits.
Three Pillars of EBP
Three Pillars of EBP
Scientific research, clinical expertise, and patient values/circumstances.
Scientific Research
Scientific Research
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Clinical Expertise
Clinical Expertise
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Patient's Values
Patient's Values
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Five Steps of EBP
Five Steps of EBP
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Descriptive Research Questions
Descriptive Research Questions
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Predictive Research Questions
Predictive Research Questions
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Causal Study
Causal Study
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Descriptive Study Designs
Descriptive Study Designs
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Predictive Study Designs
Predictive Study Designs
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Randomization
Randomization
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Blinding
Blinding
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Sham Group
Sham Group
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P-value
P-value
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Confidence Intervals (CIs)
Confidence Intervals (CIs)
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Type I Error
Type I Error
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Type II Error
Type II Error
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Intra-rater Reliability
Intra-rater Reliability
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Inter-rater Reliability
Inter-rater Reliability
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Nominal Scale
Nominal Scale
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Ordinal Scale
Ordinal Scale
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Hypothesis Testing
Hypothesis Testing
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Standard Error of Measurement (SEM)
Standard Error of Measurement (SEM)
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Chi-Square
Chi-Square
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T-Test
T-Test
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Effect Size
Effect Size
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Number Needed to Treat (NNT)
Number Needed to Treat (NNT)
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Intention-to-Treat (ITT) Analysis
Intention-to-Treat (ITT) Analysis
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Shared Informed Decision
Shared Informed Decision
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Appraisal Process
Appraisal Process
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Study Notes
Evidence-Based Practice (EBP) Foundations
- EBP integrates best research, clinical expertise, and patient values for optimal patient care.
- EBP guides treatment choices and highlights effective vs. ineffective approaches.
- EBP optimizes therapy benefits and patient responsiveness.
The Three Pillars of EBP
- Scientific Research: Empirically tested hypotheses using clinical (human subjects) and non-clinical studies (healthy humans, animals, etc.).
- Clinical Expertise: Accumulated knowledge of physical therapy gleaned from experience and improved techniques.
- Patient Values & Circumstances: Patient's beliefs, preferences, medical history, access to care, and family environment.
Five Steps of EBP
- Identify: Formulate a focused clinical question.
- Search: Gather the best research evidence.
- Appraise: Critically assess the evidence's quality and applicability.
- Integrate: Combine evidence with clinical expertise and patient factors.
- Evaluate: Assess the effectiveness and identify improvements.
Types of Research Questions
- Descriptive: Summarizes a situation (e.g., patient demographics).
- Predictive: Foresees future outcomes based on current data (longitudinal studies).
- Causal: Aims to show cause-effect relationships (e.g., intervention vs. control).
Study Designs
- Descriptive: Cross-sectional, longitudinal surveys, clinical notes, health system data.
- Predictive: Cross-sectional, longitudinal surveys, clinical notes, health systems data, observational cohort studies, qualitative studies.
- Causal: Randomized controlled trials (RCTs), quasi-RCTs, controlled cohorts, natural experiments, case-control studies, longitudinal or mediation analyses.
Key Concepts in Research
- Prediction vs. Causation: Predicting future outcomes vs. proving cause-and-effect.
- Randomization: Random assignment to groups to avoid bias.
- Blinding: Concealing treatment group information from participants, clinicians, or both (single, double, or triple blinding).
- Sham Group: Used as a control to account for placebo effects.
Literature Searching
- Google Scholar: Comprehensive search engine for peer-reviewed and non-peer-reviewed research.
- PubMed: Medical database with MeSH terms for refined searches, clinical queries and citations.
- PEDro: Physiotherapy Evidence Database.
- Cochrane Library: Systematic reviews and summaries.
- AHRQ: Agency for Healthcare Research and Quality.
Study Appraisal
- Applicability: How well the study fits the specific patient population and setting.
- Quality: Rigorous study design and execution.
- Realistic Intervention, Relevant Outcomes, Adequate Follow-up, Participant Attrition, Original Group Preservation.
- Surrogate Outcomes: Indirect measures of clinical outcomes.
- Conflicts of Interest: Financial or other interests that could bias the study.
- Reporting Bias: Potential for published studies to overrepresent positive findings.
Statistical Concepts
- Descriptive Statistics: Summarize data (mean, median, mode, standard deviation).
- Inferential Statistics: Draw conclusions from data using probability (p-value, confidence intervals (CIs)).
- Reliability: Consistency of measurements (inter-rater, intra-rater).
- Validity: Measures what it's intended to measure.
- Scales of Measurement: Nominal, ordinal, interval, ratio.
- Statistical Tests: T-tests, ANOVA, chi-square, ICC, Spearman's Rho, Kappa, etc.
Clinical Relevance
- Effect Size (Cohen's d): Magnitude of treatment differences (small, medium, large).
- Number Needed to Treat (NNT): How many patients need to be treated for one to benefit.
Barriers to EBP
- Time constraints, lack of research skills, limited resources, inconsistent EBP culture.
Shared Informed Decision
- Collaborative decision-making based on evidence and patient values.
Appraisal Process Summary
- Four parts:
- Applicability
- Quality
- Results
- Clinical Bottom Line
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Description
Explore the essential components of Evidence-Based Practice (EBP) in healthcare. This quiz covers the integration of scientific research, clinical expertise, and patient values, along with the critical steps involved in applying EBP for optimal patient care. Test your understanding of how these elements work together to enhance treatment outcomes.