Etomidate Overview and Clinical Use

What is the class of Etomidate?

What is the mechanism of action of Etomidate?

What are the indications for using Etomidate?

What is a primary contraindication for Etomidate?

What is a precaution when using Etomidate in patients?

How can Etomidate affect patients with known heart failure?

What should be considered in patients with renal failure when using Etomidate?

What is recommended for elderly patients or those in suspected shock when using Etomidate?

What are some common adverse reactions to Etomidate?

What must be avoided when using Etomidate in relation to drug interactions?

The dosage for Etomidate is _____ mg/kg IV/IO (maximum single dose 30 mg).

For elderly patients or those in shock, the dosage for Etomidate is _____ mg/kg.

Etomidate Overview

General anesthetic and sedative used for rapid induction of anesthesia.
Minimum cardiovascular effects make it suitable for high-risk patients.

Mechanism of Action

Short-acting, nonbarbiturate anesthetic.
Facilitates quick onset of anesthesia.

Indications

Primarily indicated for Rapid Sequence Intubation (RSI) to facilitate endotracheal intubation.

Contraindications

Not to be used in patients with a known hypersensitivity to Etomidate.

Precautions and Warnings

Inhibits adrenal steroid production effectively for up to 8 hours, and longer (up to 24 hours) in elderly or debilitated patients.
Can worsen heart failure symptoms; caution is advised in these patients.
Use with caution in those with renal failure; renal function assessment is recommended.
Consider halving the dose in elderly patients or those suspected to be in shock to mitigate cardiac depressive effects.

Adverse Reactions

Common adverse reactions include nausea and vomiting.
Other side effects may include hiccups and adrenal suppression.

Drug Interactions

Contraindicated in patients taking benznidazole or metronidazole due to potential adverse reactions.

Dosage and Route

Standard dosage is 0.3 mg/kg given intravenously or intraosseously, with a maximum single dose capped at 30 mg.
Adjusted dosage of 0.15 mg/kg recommended for elderly patients, those in shock, or those at risk of hypotension due to an increased shock index.

This quiz covers the essential aspects of Etomidate, a rapid-acting anesthetic commonly used for quick induction of anesthesia. It includes information on its mechanism of action, indications, contraindications, precautions, and potential adverse reactions. Ideal for students and professionals in anesthesiology and emergency medicine.