Epidemiology and Management of Bone Marrow Disorders
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Epidemiology and Management of Bone Marrow Disorders

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Questions and Answers

What is a primary complication associated with Aplastic Anemia?

  • Hemorrhage (correct)
  • Chronic fatigue syndrome
  • Increased cellular and tissue perfusion
  • Decreased red blood cell production
  • Which laboratory test is NOT typically used in diagnosing Aplastic Anemia?

  • CBC
  • Bone marrow biopsy
  • Liver function tests (correct)
  • Coagulation studies
  • Which medication is commonly used in the treatment of Aplastic Anemia?

  • Aspirin
  • Filgrastim (correct)
  • Metformin
  • Ibuprofen
  • What symptom is NOT commonly associated with Aplastic Anemia?

    <p>High fever</p> Signup and view all the answers

    Which nursing diagnosis is most relevant for a patient with Aplastic Anemia?

    <p>Activity intolerance related to decreased oxygen-carrying capacity</p> Signup and view all the answers

    What is a primary clinical manifestation associated with Aplastic Anemia?

    <p>Shortness of breath</p> Signup and view all the answers

    Which of the following is a common complication of Aplastic Anemia?

    <p>Decreased cellular and tissue perfusion</p> Signup and view all the answers

    In the medical management of Aplastic Anemia, which treatment option is considered important for severe cases?

    <p>Blood transfusions</p> Signup and view all the answers

    Which vital sign change may indicate a worsening condition in a patient with Aplastic Anemia?

    <p>Elevated heart rate</p> Signup and view all the answers

    What nursing intervention is critical to prevent injury in patients with Aplastic Anemia?

    <p>Limit physical activity</p> Signup and view all the answers

    Study Notes

    Epidemiology

    • Affects 2 to 4 people per million in the US
    • Occurs equally in men and women

    Pathophysiology

    • Damage to bone marrow occurs
    • Decreased production of red blood cells results

    Clinical Manifestations

    • Fatigue
    • Shortness of breath
    • Tachycardia
    • Pallor
    • Dizziness
    • Headache
    • Susceptibility to infections
    • Bleeding

    Medical Management - Diagnosis

    • Laboratory tests including:
      • CBC
      • Coagulation studies
      • Iron levels
      • Decreased platelets, WBCs, and RBCs are indicative
    • Bone marrow biopsy

    Medical Management - Treatment

    • Blood transfusions
    • Bone marrow transplant

    Medical Management - Medications

    • Filgrastim
    • Epoetin-alfa

    Complications

    • Decreased cellular and tissue perfusion
    • Hemorrhage
    • Severe infection

    Nursing Management - Assessment and Analysis

    • Patients are at risk for decreased oxygen-carrying capacity, infection, and bleeding.

    Nursing Management - Nursing Diagnoses

    • Activity intolerance
    • Risk for injury
    • Risk for infection

    Nursing Interventions - Assessments

    • Vital signs
    • Laboratory tests
    • Oxygen saturation
    • Signs of bleeding
    • Fatigue and pallor
    • Dizziness and headache

    Nursing Interventions - Actions

    • Provide supplemental oxygen
    • Administer blood products
    • Implement bleeding precautions
    • Protect from injury

    Nursing Interventions - Teaching

    • Avoid exposure to infection
    • Report temperature elevation
    • Avoid activities with potential for injury
    • Be aware of the clinical manifestations of anemia
    • Focus on nutritional intake

    Nursing Management - Evaluating Care Outcomes

    • Stable CBC and platelets
    • Absence of infection
    • Absence of bleeding

    Epidemiology

    • Aplastic anemia affects 2 to 4 people per million in the US.
    • The condition affects males and females equally.

    Pathophysiology

    • Bone marrow damage leads to decreased production of red blood cells.

    Clinical Manifestations

    • Fatigue
    • Shortness of breath
    • Tachycardia (fast heart rate)
    • Pallor (paleness)
    • Dizziness
    • Headache
    • Susceptibility to infections
    • Bleeding

    Medical Management - Diagnosis

    • Complete blood count (CBC)
    • Coagulation studies
    • Iron levels
    • Decreased platelets, white blood cells (WBCs), and red blood cells (RBCs)
    • Bone marrow biopsy

    Medical Management - Treatment

    • Blood transfusions
    • Bone marrow transplant

    Medical Management - Medications

    • Filgrastim
    • Epoetin-alfa

    Complications

    • Decreased cellular and tissue perfusion (oxygen delivery)
    • Hemorrhage (excessive bleeding)
    • Severe infection

    Nursing Management - Assessments and Analysis

    • Patients are at risk for:
      • Decreased oxygen-carrying capacity
      • Infection
      • Bleeding

    Nursing Management - Nursing Diagnoses

    • Activity intolerance
    • Risk for injury
    • Risk for infection

    Nursing Interventions - Assessments

    • Vital signs
    • Laboratory tests
    • Oxygen saturation
    • Signs of bleeding
    • Fatigue and pallor
    • Dizziness and headache

    Nursing Interventions - Actions

    • Provide supplemental oxygen
    • Administer blood products
    • Implement bleeding precautions
    • Protect from injury

    Nursing Interventions - Teaching

    • Avoid exposure to infection
    • Report temperature elevation
    • Avoid activities with potential for injury
    • Understand clinical manifestations of anemia
    • Maintain proper nutritional intake

    Nursing Management - Evaluating Care Outcomes

    • Stable CBC and platelet levels
    • Absence of infection
    • Absence of bleeding

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    Description

    This quiz covers the key aspects of bone marrow disorders, including epidemiology, pathophysiology, clinical manifestations, medical management, and nursing assessments. Test your knowledge on diagnostic tests, treatment options, and potential complications related to these conditions.

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