Enzyme Catalysis and Transition State Theory
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Questions and Answers

What is the role of enzymes in a reaction?

  • Change the equilibrium constant of the reaction
  • Decrease the activation energy (correct)
  • Change the overall delta G of the reaction
  • Increase the activation energy
  • Under what condition would an enzyme be saturated?

  • High substrate concentration (correct)
  • Low substrate concentration
  • High enzyme concentration
  • Low enzyme concentration
  • What does the Michaelis constant (Km) represent?

  • The substrate concentration needed for 1/2Vmax (correct)
  • The rate of reaction at Vmax
  • The enzyme-substrate affinity
  • The enzyme concentration required to reach Vmax
  • How do changes in pH affect enzyme activity?

    <p>Decrease enzyme activity</p> Signup and view all the answers

    Which structure do proteins need to fold into to function properly?

    <p>Tertiary structure</p> Signup and view all the answers

    What happens to enzyme function at very high substrate concentrations?

    <p>Enzymes reach Vmax</p> Signup and view all the answers

    What is the main purpose of acid/base catalysis in enzymes?

    <p>To make reactions go faster by proton transfer</p> Signup and view all the answers

    Where do enzymes lower the activation energy of a reaction?

    <p>At the transition state</p> Signup and view all the answers

    What model explains the phenomenon where enzymes and substrates change their shape slightly to bind together tightly?

    <p>Induced-fit Model</p> Signup and view all the answers

    What type of catalysis involves charged molecules or metal ions to stabilize big positive or negative charges?

    <p>Electrostatic Catalysis</p> Signup and view all the answers

    In enzyme-substrate specificity, what is responsible for determining the specificity of an enzyme?

    <p>Active site shape and characteristics</p> Signup and view all the answers

    Which model describes the location on an enzyme where it reacts with its substrate?

    <p>Active Site Model</p> Signup and view all the answers

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