Enzyme Catalysis and Transition State Theory

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12 Questions

What is the role of enzymes in a reaction?

Decrease the activation energy

Under what condition would an enzyme be saturated?

High substrate concentration

What does the Michaelis constant (Km) represent?

The substrate concentration needed for 1/2Vmax

How do changes in pH affect enzyme activity?

Decrease enzyme activity

Which structure do proteins need to fold into to function properly?

Tertiary structure

What happens to enzyme function at very high substrate concentrations?

Enzymes reach Vmax

What is the main purpose of acid/base catalysis in enzymes?

To make reactions go faster by proton transfer

Where do enzymes lower the activation energy of a reaction?

At the transition state

What model explains the phenomenon where enzymes and substrates change their shape slightly to bind together tightly?

Induced-fit Model

What type of catalysis involves charged molecules or metal ions to stabilize big positive or negative charges?

Electrostatic Catalysis

In enzyme-substrate specificity, what is responsible for determining the specificity of an enzyme?

Active site shape and characteristics

Which model describes the location on an enzyme where it reacts with its substrate?

Active Site Model

Explore the different types of enzyme catalysis, including acid/base, covalent, and electrostatic mechanisms. Learn about how enzymes facilitate reactions through proximity and orientation effects, and understand the concept of transition state as the highest energy point in a reaction pathway.

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