Enzyme Activators and Inhibitors Quiz
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Questions and Answers

Which substance is an inhibitor of Hexokinase?

  • NADH
  • AMP
  • ADP
  • Fructose-6-phosphate (correct)

What is an activator for Pyruvate kinase?

  • Fructose-1,6-bisphosphate (correct)
  • Acetyl-CoA
  • ATP
  • Citrate

Fructose-2,6-bisphosphate is an activator for which enzyme?

  • Lactate dehydrogenase
  • Hexokinase
  • Pyruvate kinase
  • PFK-1 (correct)

Which of the following is NOT an inhibitor of PFK-1?

<p>AMP (D)</p> Signup and view all the answers

Which enzyme is inhibited by Acetyl-CoA?

<p>Pyruvate kinase (B)</p> Signup and view all the answers

Which inhibitor is specific to Hexokinase?

<p>Glucose-6-phosphate (B)</p> Signup and view all the answers

Which of the following combinations contains only activators for Pyruvate kinase?

<p>AMP, Fructose-1,6-bisphosphate (D)</p> Signup and view all the answers

Which substance inhibits both PFK-1 and Pyruvate kinase?

<p>ATP (A)</p> Signup and view all the answers

Identifying the unique activator for PFK-1, which of the following is it?

<p>Fructose-2,6-bisphosphate (A)</p> Signup and view all the answers

Which of the following substances is an activator and NOT an inhibitor for any enzyme listed?

<p>AMP (C)</p> Signup and view all the answers

Flashcards

Hexokinase activator

AMP, ADP, inorganic phosphate ($P_i$), and Fructose-6-phosphate activate Hexokinase.

Hexokinase inhibitor

Glucose-6-phosphate inhibits Hexokinase.

PFK-1 activator

Fructose-2,6-bisphosphate activates PFK-1.

PFK-1 inhibitor

NADH, Citrate, and ATP inhibit PFK-1.

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Pyruvate Kinase inhibitor

ATP and Acetyl-CoA inhibit Pyruvate Kinase.

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Hexokinase activator

AMP, ADP, inorganic phosphate (Pi), and Fructose-6-phosphate activate Hexokinase.

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PFK-1 inhibitor

NADH, Citrate, and ATP inhibit phosphofructokinase-1 (PFK-1).

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PFK-1 activator

Fructose-2,6-bisphosphate activates PFK-1.

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Pyruvate kinase inhibitor

ATP and Acetyl-CoA inhibit Pyruvate kinase.

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Hexokinase inhibitor

Glucose-6-phosphate inhibits Hexokinase.

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Study Notes

Enzyme Activators and Inhibitors

  • Hexokinase:

    • Activators: AMP, ADP, Pi, Fructose-6-phosphate
    • Inhibitor: Glucose-6-phosphate
  • PFK-1:

    • Activator: Fructose-2,6-bisphosphate
    • Inhibitors: NADH, Citrate, ATP
  • Pyruvate Kinase:

    • Activators: AMP, Fructose-1,6-bisphosphate
    • Inhibitors: ATP, Acetyl-CoA

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Description

Test your knowledge on enzyme activators and inhibitors, focusing on Hexokinase, PFK-1, and Pyruvate Kinase. This quiz covers the key compounds that activate or inhibit these enzymes, helping you understand metabolic regulation better.

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