Enzyme Activators and Inhibitors Quiz

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Questions and Answers

Which of the following is an inhibitor of hexokinase?

  • AMP
  • P_i
  • ADP
  • Fructose-6-phosphate (correct)

What is an activator of PFK-1?

  • Citrate
  • NADH
  • ATP
  • Fructose-2,6-bisphosphate (correct)

Which of the following is NOT an inhibitor of pyruvate kinase?

  • Fructose-1,6-bisphosphate
  • ATP
  • Acetyl-CoA
  • AMP (correct)

Which combination correctly identifies an enzyme and its activator?

<p>Pyruvate kinase - Fructose-1,6-bisphosphate (B)</p> Signup and view all the answers

What is a common inhibitor of both PFK-1 and pyruvate kinase?

<p>ATP (A)</p> Signup and view all the answers

Flashcards

Hexokinase activator

AMP, ADP, $P_i$, and Fructose-6-phosphate activate Hexokinase.

Hexokinase inhibitor

Glucose-6-phosphate inhibits Hexokinase.

PFK-1 activator

Fructose-2,6-bisphosphate activates PFK-1.

PFK-1 inhibitors

NADH, Citrate, and ATP inhibit PFK-1.

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Pyruvate kinase activator

AMP and Fructose-1,6-bisphosphate activate Pyruvate kinase.

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Pyruvate kinase inhibitor

ATP and Acetyl-CoA inhibit Pyruvate kinase.

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Study Notes

Enzyme Activators and Inhibitors

  • Hexokinase:

    • Activators: AMP, ADP, Pi
    • Inhibitors: Glucose-6-phosphate
  • PFK-1:

    • Activators: Fructose-2,6-bisphosphate
    • Inhibitors: NADH, Citrate, ATP
  • Pyruvate kinase:

    • Activators: AMP, Fructose-1,6-bisphosphate
    • Inhibitors: ATP, Acetyl-CoA

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