Podcast
Questions and Answers
What is one of the mechanisms by which environmental factors induce autoimmunity?
What is one of the mechanisms by which environmental factors induce autoimmunity?
- Immune system overactivation
- Genetic mutations
- Hormonal imbalances
- Epigenetic changes (correct)
What is the result of exposure of DNA and small nuclear ribonucleoproteins to UV-B radiation?
What is the result of exposure of DNA and small nuclear ribonucleoproteins to UV-B radiation?
- Changes to the conformation and location of DNA and snRNPs (correct)
- Inhibition of autoreactive lymphocytes
- Activation of immune complexes
- Production of novel antigens
What is the effect of environmental toxins on the immune system?
What is the effect of environmental toxins on the immune system?
- Activation of autoreactive lymphocytes (correct)
- Production of antibodies
- Inhibition of cytokine production
- Suppression of immune responses
What is the link between certain chemical agents and autoimmune diseases?
What is the link between certain chemical agents and autoimmune diseases?
What is the primary reason for interpreting findings at diagnosis with findings at initiation?
What is the primary reason for interpreting findings at diagnosis with findings at initiation?
What is the result of exposure to UV radiation in patients with SLE?
What is the result of exposure to UV radiation in patients with SLE?
How many phases are involved in the development of ADs?
How many phases are involved in the development of ADs?
What is the role of epigenetic changes in autoimmune diseases?
What is the role of epigenetic changes in autoimmune diseases?
What can trigger the initiation phase of ADs?
What can trigger the initiation phase of ADs?
What is the characteristic of the propagation phase of ADs?
What is the characteristic of the propagation phase of ADs?
What can occur during the propagation phase of ADs?
What can occur during the propagation phase of ADs?
How are ADs usually categorized?
How are ADs usually categorized?
What type of infections can provoke the initiation of systemic autoimmune diseases in genetically predisposed individuals?
What type of infections can provoke the initiation of systemic autoimmune diseases in genetically predisposed individuals?
What can a severe bacterial or viral infection trigger in individuals with autoimmune diseases?
What can a severe bacterial or viral infection trigger in individuals with autoimmune diseases?
What is a common feature of many autoimmune diseases in both humans and experimental animal models?
What is a common feature of many autoimmune diseases in both humans and experimental animal models?
What do researchers hypothesize about the role of hormones in autoimmune diseases?
What do researchers hypothesize about the role of hormones in autoimmune diseases?
What is often abnormal in patients with systemic lupus erythematosus (SLE)?
What is often abnormal in patients with systemic lupus erythematosus (SLE)?
What is a characteristic of many autoimmune diseases in terms of regional and ethnic differences?
What is a characteristic of many autoimmune diseases in terms of regional and ethnic differences?
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