Enfermedades Neurodegenerativas y Alzheimer
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Questions and Answers

¿Cuáles de estas características son propias de las enfermedades neurodegenerativas?

  • Pérdidas selectivas de neuronas (correct)
  • Causa conocida
  • Progresivas (correct)
  • Inicio súbito

La enfermedad de Alzheimer es un desorden neurodegenerativo común en adultos mayores de 65 años.

True (A)

¿Cuáles son las mutaciones genéticas asociadas con la aparición temprana de péptidos amiloide-β en la enfermedad de Alzheimer?

APP y PSEN1-2

La enfermedad de Alzheimer se caracteriza por la presencia de placas extracelulares de péptidos ________ y ovillos neurofibrilares de la proteína tau.

<p>amiloide-β</p> Signup and view all the answers

Relaciona los neurotransmisores con sus niveles en la enfermedad de Alzheimer:

<p>Acetilcolina = Bajos Serotonina = Bajos Dopamina = Bajos Glutamato = Altos GABA = Altos</p> Signup and view all the answers

¿Cómo se realiza el diagnóstico de la enfermedad de Alzheimer?

<p>Clínicamente, incluye entrevista al paciente, examen físico, evaluación neurocognitiva y estudios de neuroimágenes.</p> Signup and view all the answers

Las enfermedades neurodegenerativas tienen siempre una causa conocida.

<p>False (B)</p> Signup and view all the answers

Flashcards

Neurodegenerative Diseases

A group of diseases characterized by selective and symmetrical loss of neurons in motor, sensory, and cognitive systems

Parkinson's disease

A neurodegenerative disease causing tremors, rigidity, and difficulty with movement.

Huntington's disease

A neurodegenerative disease affecting movement, cognition, and behavior

Alzheimer's disease

Most common type of dementia, caused by amyloid plaques and tau tangles.

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Amyloid plaques

Extracellular deposits of proteins in the brain, characteristic of Alzheimer's.

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Tau tangles

Abnormal aggregations of the tau protein inside neurons, found in Alzheimer's.

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Dementia

A group of symptoms affecting the ability to think, remember, and reason.

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Neurotransmitters

Chemical messengers that transmit signals between neurons.

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Cognitive-behavioral evaluation

Assessment of cognitive and behavioral function, crucial in diagnosing dementia.

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DSM-IV

Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (now updated).

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