Podcast
Questions and Answers
Why is the physiology of the endothelium particularly important to pharmacists?
Why is the physiology of the endothelium particularly important to pharmacists?
- It does not interact with vasoactive substances
- It has no impact on drug absorption
- It regulates the movement of small and large molecules (correct)
- It functions as an inert tube lining
What is the role of L-NAME in the mechanism of endothelial-dependent vascular smooth muscle cell (VSMC) relaxation?
What is the role of L-NAME in the mechanism of endothelial-dependent vascular smooth muscle cell (VSMC) relaxation?
- Inhibits NO release (correct)
- Increases responsiveness to contractile agents
- Stimulates the release of NO
- Enhances vasorelaxation
How does the presence of an endothelial layer affect the impact of phenylephrine and nor-adrenaline on arterial tone?
How does the presence of an endothelial layer affect the impact of phenylephrine and nor-adrenaline on arterial tone?
- Completely inhibits their action
- Enhances their effect on arterial tone
- Has no impact on arterial tone
- Reduces their effect on arterial tone (correct)
What is the primary function of nitrovasodilators in clinical use?
What is the primary function of nitrovasodilators in clinical use?
Which statement regarding NO release from endothelial cells is true?
Which statement regarding NO release from endothelial cells is true?
How do organic nitrates primarily impact intracellular levels?
How do organic nitrates primarily impact intracellular levels?
Which of the following is NOT a function of the endothelial cells?
Which of the following is NOT a function of the endothelial cells?
What is the name of the molecule discovered by Salvador Moncada in 1976 that regulates vascular tone?
What is the name of the molecule discovered by Salvador Moncada in 1976 that regulates vascular tone?
What is the name of the molecule initially known as EDRF (endothelium-derived relaxing factor) that was discovered by Furchgott and Zawadzki in 1980?
What is the name of the molecule initially known as EDRF (endothelium-derived relaxing factor) that was discovered by Furchgott and Zawadzki in 1980?
Which of the following phenotypes is associated with endothelial cell dysfunction?
Which of the following phenotypes is associated with endothelial cell dysfunction?
According to the image, what do the green and red fluorescent colors represent in a blood vessel?
According to the image, what do the green and red fluorescent colors represent in a blood vessel?
Which of the following statements about the endothelium is correct?
Which of the following statements about the endothelium is correct?
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