Endocrinology: Hypothalamic-Pituitary Hormones

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Questions and Answers

What is the mechanism of action of bromocriptine in reducing serum prolactin concentrations?

  • Inhibiting oxytocin release
  • Blocking dopamine receptors
  • Stimulating dopamine receptors
  • Agonizing dopamine receptors (correct)

Which type of pharmacologic action is most likely to cause hyperprolactinemia?

  • Dopamine receptor antagonism (correct)
  • Oxytocin receptor antagonism
  • Dopamine receptor agonism
  • Dopamine receptor modulation

What is the effect of oxytocin on uterine contraction?

  • Stimulates uterine contraction (correct)
  • Has no effect on uterine contraction
  • Modulates oxytocin receptors
  • Inhibits uterine contraction

What is the mechanism of action of atosiban?

<p>Antagonizing oxytocin receptors (B)</p> Signup and view all the answers

What is the effect of dopamine agonists on serum prolactin concentrations?

<p>Decreases serum prolactin concentrations (C)</p> Signup and view all the answers

What is the cause of amenorrhea in women with hyperprolactinemia?

<p>Increased prolactin levels (B)</p> Signup and view all the answers

What is the mechanism of action of prolactin and posterior pituitary hormones?

<p>They act directly on target tissues. (D)</p> Signup and view all the answers

What is the role of hypothalamic factors in the regulation of anterior pituitary hormones?

<p>They regulate the release of anterior pituitary hormones. (C)</p> Signup and view all the answers

What is the effect of somatostatin on hormone release?

<p>It inhibits the release of GH, glucagon, insulin, and gastrin. (B)</p> Signup and view all the answers

What is the purpose of administering a snack or meal shortly before mecasermin administration?

<p>To reduce the side effects of mecasermin. (C)</p> Signup and view all the answers

What is the advantage of mecasermin rinfabate over mecasermin?

<p>It has a longer half-life. (B)</p> Signup and view all the answers

What is the advantage of the slow-release intramuscular formulation of octreotide or lanreotide over regular octreotide?

<p>It needs to be administered less frequently. (A)</p> Signup and view all the answers

What is the mechanism of action of somatostatin analogs?

<p>Somatostatin receptor agonist (B)</p> Signup and view all the answers

How does recombinant human GH act?

<p>Through GH receptors (D)</p> Signup and view all the answers

What is the mechanism of action of ganirelix?

<p>GnRH receptor antagonist (C)</p> Signup and view all the answers

How does leuprolide act?

<p>GnRH receptor agonist (C)</p> Signup and view all the answers

What is the mechanism of action of desmopressin?

<p>Vasopressin V2 receptor agonist (C)</p> Signup and view all the answers

How does oxytocin act?

<p>Oxytocin receptor agonist (B)</p> Signup and view all the answers

What is the mechanism of action of pegvisomant?

<p>Growth hormone receptor antagonist (A)</p> Signup and view all the answers

How does mecasermin act?

<p>IGF-1 agonist (D)</p> Signup and view all the answers

What is the mechanism of action of atosiban?

<p>Oxytocin receptor antagonist (C)</p> Signup and view all the answers

How does bromocriptine act?

<p>Dopamine D2 receptor agonist (C)</p> Signup and view all the answers

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