22 Questions
What is the mechanism of action of bromocriptine in reducing serum prolactin concentrations?
Agonizing dopamine receptors
Which type of pharmacologic action is most likely to cause hyperprolactinemia?
Dopamine receptor antagonism
What is the effect of oxytocin on uterine contraction?
Stimulates uterine contraction
What is the mechanism of action of atosiban?
Antagonizing oxytocin receptors
What is the effect of dopamine agonists on serum prolactin concentrations?
Decreases serum prolactin concentrations
What is the cause of amenorrhea in women with hyperprolactinemia?
Increased prolactin levels
What is the mechanism of action of prolactin and posterior pituitary hormones?
They act directly on target tissues.
What is the role of hypothalamic factors in the regulation of anterior pituitary hormones?
They regulate the release of anterior pituitary hormones.
What is the effect of somatostatin on hormone release?
It inhibits the release of GH, glucagon, insulin, and gastrin.
What is the purpose of administering a snack or meal shortly before mecasermin administration?
To reduce the side effects of mecasermin.
What is the advantage of mecasermin rinfabate over mecasermin?
It has a longer half-life.
What is the advantage of the slow-release intramuscular formulation of octreotide or lanreotide over regular octreotide?
It needs to be administered less frequently.
What is the mechanism of action of somatostatin analogs?
Somatostatin receptor agonist
How does recombinant human GH act?
Through GH receptors
What is the mechanism of action of ganirelix?
GnRH receptor antagonist
How does leuprolide act?
GnRH receptor agonist
What is the mechanism of action of desmopressin?
Vasopressin V2 receptor agonist
How does oxytocin act?
Oxytocin receptor agonist
What is the mechanism of action of pegvisomant?
Growth hormone receptor antagonist
How does mecasermin act?
IGF-1 agonist
What is the mechanism of action of atosiban?
Oxytocin receptor antagonist
How does bromocriptine act?
Dopamine D2 receptor agonist
This quiz covers the roles of prolactin, vasopressin, oxytocin, and other hormones released from the pituitary gland, as well as the regulation of anterior pituitary hormones by hypothalamic factors. Test your knowledge of endocrinology!
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