Endocrinology: Hypothalamic-Pituitary Hormones
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Questions and Answers

What is the mechanism of action of bromocriptine in reducing serum prolactin concentrations?

  • Inhibiting oxytocin release
  • Blocking dopamine receptors
  • Stimulating dopamine receptors
  • Agonizing dopamine receptors (correct)

    • Which type of pharmacologic action is most likely to cause hyperprolactinemia?

  • Dopamine receptor antagonism (correct)
  • Oxytocin receptor antagonism
  • Dopamine receptor agonism
  • Dopamine receptor modulation

    • What is the effect of oxytocin on uterine contraction?

  • Stimulates uterine contraction (correct)
  • Has no effect on uterine contraction
  • Modulates oxytocin receptors
  • Inhibits uterine contraction

    • What is the mechanism of action of atosiban?

    <p>Antagonizing oxytocin receptors</p> Signup and view all the answers

    What is the effect of dopamine agonists on serum prolactin concentrations?

    <p>Decreases serum prolactin concentrations</p> Signup and view all the answers

    What is the cause of amenorrhea in women with hyperprolactinemia?

    <p>Increased prolactin levels</p> Signup and view all the answers

    What is the mechanism of action of prolactin and posterior pituitary hormones?

    <p>They act directly on target tissues.</p> Signup and view all the answers

    What is the role of hypothalamic factors in the regulation of anterior pituitary hormones?

    <p>They regulate the release of anterior pituitary hormones.</p> Signup and view all the answers

    What is the effect of somatostatin on hormone release?

    <p>It inhibits the release of GH, glucagon, insulin, and gastrin.</p> Signup and view all the answers

    What is the purpose of administering a snack or meal shortly before mecasermin administration?

    <p>To reduce the side effects of mecasermin.</p> Signup and view all the answers

    What is the advantage of mecasermin rinfabate over mecasermin?

    <p>It has a longer half-life.</p> Signup and view all the answers

    What is the advantage of the slow-release intramuscular formulation of octreotide or lanreotide over regular octreotide?

    <p>It needs to be administered less frequently.</p> Signup and view all the answers

    What is the mechanism of action of somatostatin analogs?

    <p>Somatostatin receptor agonist</p> Signup and view all the answers

    How does recombinant human GH act?

    <p>Through GH receptors</p> Signup and view all the answers

    What is the mechanism of action of ganirelix?

    <p>GnRH receptor antagonist</p> Signup and view all the answers

    How does leuprolide act?

    <p>GnRH receptor agonist</p> Signup and view all the answers

    What is the mechanism of action of desmopressin?

    <p>Vasopressin V2 receptor agonist</p> Signup and view all the answers

    How does oxytocin act?

    <p>Oxytocin receptor agonist</p> Signup and view all the answers

    What is the mechanism of action of pegvisomant?

    <p>Growth hormone receptor antagonist</p> Signup and view all the answers

    How does mecasermin act?

    <p>IGF-1 agonist</p> Signup and view all the answers

    What is the mechanism of action of atosiban?

    <p>Oxytocin receptor antagonist</p> Signup and view all the answers

    How does bromocriptine act?

    <p>Dopamine D2 receptor agonist</p> Signup and view all the answers

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