JC HBHD 2 Week 5 Chapter 12 Endocrine
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Questions and Answers

Which of the following is NOT a principal function of a major endocrine hormone?

  • Maintenance of homeostasis
  • Regulation of metabolism
  • Production of digestive enzymes (correct)
  • Control of growth and development
  • What is the difference between endocrine and exocrine glands?

  • Endocrine glands release secretions into ducts, while exocrine glands release hormones directly into the bloodstream.
  • Endocrine glands release hormones directly into the bloodstream, while exocrine glands release their secretions into ducts. (correct)
  • Endocrine glands produce hormones, while exocrine glands produce enzymes.
  • Endocrine glands are found in the brain, while exocrine glands are found in other organs.
  • Which of the following accurately describes the mechanism of steroid hormone action?

  • Steroid hormones diffuse through the cell membrane and bind to receptors in the cytoplasm or nucleus. (correct)
  • Steroid hormones act directly on DNA to regulate gene expression.
  • Steroid hormones act as second messengers, relaying signals from the cell membrane to the nucleus.
  • Steroid hormones bind to receptors on the cell membrane, triggering a cascade of intracellular events.
  • What is the role of negative feedback mechanisms in regulating endocrine hormone secretion?

    <p>Negative feedback increases hormone secretion when levels are low and decreases secretion when levels are high. (D)</p> Signup and view all the answers

    What are prostaglandins (PGs) and why are they important?

    <p>PGs are hormone-like substances that act locally to regulate various physiological processes. (B)</p> Signup and view all the answers

    Which of the following hormones is responsible for stimulating the growth of the adrenal cortex and its secretion of glucocorticoids?

    <p>Adrenocorticotropic hormone (ACTH) (D)</p> Signup and view all the answers

    What could potentially happen if there was a deficiency in growth hormone (GH) during childhood?

    <p>Pituitary dwarfism (C)</p> Signup and view all the answers

    Which of the following is NOT a function of luteinizing hormone (LH)?

    <p>Stimulates the secretion of thyroid hormone (C)</p> Signup and view all the answers

    What is the role of antidiuretic hormone (ADH) in the body?

    <p>It accelerates the reabsorption of water from urine in the kidneys. (A)</p> Signup and view all the answers

    What is the primary difference between the anterior pituitary gland and the posterior pituitary gland?

    <p>The anterior pituitary gland is made up of nervous tissue, while the posterior pituitary gland is made up of glandular tissue. (B)</p> Signup and view all the answers

    Which of the following hormones is responsible for stimulating milk production after childbirth?

    <p>Prolactin (PRL) (B)</p> Signup and view all the answers

    What is the condition caused by hyposecretion of the thyroid hormones?

    <p>Cretinism (A)</p> Signup and view all the answers

    What is the primary function of follicle-stimulating hormone (FSH) in females?

    <p>Stimulates the growth of ovarian follicles and their development for ovulation (A)</p> Signup and view all the answers

    Which hormone is responsible for initiating labor and milk release from the mammary glands?

    <p>Oxytocin (OT) (A)</p> Signup and view all the answers

    What is the function of calcitonin in relation to calcium levels?

    <p>It decreases blood calcium levels by inhibiting bone breakdown. (C)</p> Signup and view all the answers

    Which of the following is the most likely consequence of an excess of growth hormone (GH) during adulthood?

    <p>Acromegaly (D)</p> Signup and view all the answers

    Which of the following best describes the effect of thyroid-stimulating hormone (TSH) on the thyroid gland?

    <p>TSH promotes the growth of the thyroid gland and its secretion of thyroid hormone (B)</p> Signup and view all the answers

    What is the primary role of the hypothalamus in relation to the posterior pituitary hormones?

    <p>It produces the hormones ADH and oxytocin, but releases them from the pituitary gland. (A)</p> Signup and view all the answers

    Which of the following is a characteristic symptom of hyperthyroidism?

    <p>Restlessness and protruding eyes. (B)</p> Signup and view all the answers

    What is a goiter?

    <p>A painless enlargement of the thyroid gland caused by iodine deficiency. (A)</p> Signup and view all the answers

    Which of the following is NOT a function of thyroid hormones?

    <p>Stimulate the release of calcium from the bones. (A)</p> Signup and view all the answers

    What is the primary function of parathyroid hormone (PTH)?

    <p>Increases blood calcium concentration (A)</p> Signup and view all the answers

    Which of the following hormones is classified as a glucocorticoid?

    <p>Cortisol (C)</p> Signup and view all the answers

    What effect do mineralocorticoids have on blood sodium and potassium levels?

    <p>Increase blood sodium, decrease potassium (A)</p> Signup and view all the answers

    How do glucocorticoids respond when the body is under stress?

    <p>They increase secretion quickly (C)</p> Signup and view all the answers

    Which condition is associated with hypersecretion of glucocorticoids?

    <p>Cushing syndrome (C)</p> Signup and view all the answers

    What hormone is primarily secreted by the adrenal medulla?

    <p>Epinephrine (B)</p> Signup and view all the answers

    Which of the following is not a function of glucocorticoids?

    <p>Increasing bone density (B)</p> Signup and view all the answers

    What may occur as a result of a hyposecretion of adrenal cortical hormones?

    <p>Addison disease (D)</p> Signup and view all the answers

    Which of the following correctly describes hypersecretion?

    <p>Secretion of excess hormone (B)</p> Signup and view all the answers

    What is the primary difference between endocrine and exocrine glands?

    <p>Endocrine glands secrete directly into the bloodstream, exocrine glands secrete into ducts. (A)</p> Signup and view all the answers

    What is the role of target cells in hormone action?

    <p>Target cells detect and respond to specific hormones. (C)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of steroid hormones?

    <p>They act as first messengers, triggering second messengers. (D)</p> Signup and view all the answers

    What is the main mechanism by which hormone secretion is regulated?

    <p>Homeostatic feedback mechanisms. (B)</p> Signup and view all the answers

    What is the effect of negative feedback on hormone secretion?

    <p>It decreases the production and secretion of the hormone. (A)</p> Signup and view all the answers

    Which of the following is NOT an example of a prostaglandin?

    <p>Prostaglandin H (PGH) (D)</p> Signup and view all the answers

    What is the primary function of prostaglandins in the body?

    <p>To influence various physiological processes within specific tissues. (A)</p> Signup and view all the answers

    What is the main function of glucagon in the body?

    <p>Increase blood glucose levels (B)</p> Signup and view all the answers

    Which hormone is primarily responsible for decreasing blood glucose levels?

    <p>Insulin (C)</p> Signup and view all the answers

    What is a key cause of Type 1 Diabetes Mellitus?

    <p>Hyposecretion of insulin (A)</p> Signup and view all the answers

    What effect does estrogen have on the female body?

    <p>Initiates menstrual cycle (A)</p> Signup and view all the answers

    Which hormone is secreted by the interstitial cells of the testes?

    <p>Testosterone (D)</p> Signup and view all the answers

    What role does thymosin play in the body?

    <p>Developing the immune system (A)</p> Signup and view all the answers

    What are the hormones secreted by the placenta responsible for?

    <p>Maintaining the corpus luteum during pregnancy (C)</p> Signup and view all the answers

    What hormone does the pineal gland secrete?

    <p>Melatonin (C)</p> Signup and view all the answers

    What does ghrelin do in the body?

    <p>Boosts appetite and slows metabolism (A)</p> Signup and view all the answers

    What effect does abnormal secretion of melatonin have?

    <p>Leads to seasonal affective disorder (SAD) (A)</p> Signup and view all the answers

    A patient presents with symptoms of excessive thirst, increased urination, and unexplained weight loss. Which diagnostic test would be most appropriate to assess the patient's average blood glucose level over the past 2 to 3 months?

    <p>Glycosylated hemoglobin (HbA1c) (A)</p> Signup and view all the answers

    Which of the following conditions is characterized by an excessive secretion of the hormone aldosterone?

    <p>Hyperaldosteronism (A)</p> Signup and view all the answers

    A patient presents with symptoms of excessive hunger, excessive thirst, and frequent urination. Which of the following conditions might be suspected based on these symptoms?

    <p>Polydipsia (C)</p> Signup and view all the answers

    Which of the following diagnostic tests is used to screen for diabetes by measuring blood glucose levels after an overnight fast?

    <p>Fasting blood glucose (FBG) (B)</p> Signup and view all the answers

    Which of the following is NOT a diagnostic test or procedure discussed in the provided text?

    <p>Thyroid Stimulating Hormone (TSH) (C)</p> Signup and view all the answers

    A patient is diagnosed with a condition characterized by an overactive thyroid gland. What is the name of this condition?

    <p>Thyrotoxicosis (A)</p> Signup and view all the answers

    Which of the following diagnostic tests is used to measure blood glucose levels from a small sample of blood obtained by pricking the finger?

    <p>Finger stick blood sugar (FSBS) (A)</p> Signup and view all the answers

    Which of the following conditions is characterized by an underactive thyroid gland?

    <p>Myxedema (A)</p> Signup and view all the answers

    What is the name of the condition characterized by an overgrowth of bones, particularly in the hands, feet, and face, caused by excess growth hormone (GH) production?

    <p>Acromegaly (B)</p> Signup and view all the answers

    Which of the following endocrine disorders involves deficient production of cortisol and aldosterone by the adrenal glands, leading to symptoms like fatigue, weight loss, and low blood pressure?

    <p>Addison's Disease (B)</p> Signup and view all the answers

    What is the medical term for a condition marked by protrusion of the eyeballs, often associated with hyperthyroidism?

    <p>Exophthalmos (D)</p> Signup and view all the answers

    Which of the following conditions is characterized by excessive production of cortisol, often causing weight gain, moon face, and a buffalo hump?

    <p>Cushing's Disease (B)</p> Signup and view all the answers

    What is the medical term for a condition characterized by an enlarged thyroid gland, often caused by iodine deficiency or autoimmune disorders?

    <p>Goiter (B)</p> Signup and view all the answers

    Which type of diabetes is characterized by the pancreas's inability to produce insulin, often diagnosed in childhood or adolescence?

    <p>IDDM (B)</p> Signup and view all the answers

    Which of the following is a condition characterized by extreme thirst, frequent urination, and dehydration, due to insufficient production or action of antidiuretic hormone (ADH)?

    <p>Diabetes Insipidus (D)</p> Signup and view all the answers

    What is the common term for a condition characterized by excessive hair growth in women, sometimes associated with hormonal imbalances?

    <p>Hirsutism (D)</p> Signup and view all the answers

    Which of the following is a method of measuring the ability of the thyroid gland to concentrate and retain iodine?

    <p>Radioactive iodine uptake test (B)</p> Signup and view all the answers

    Which of the following is a method for evaluating the thyroid gland's function by measuring hormone levels?

    <p>Thyroid hormone levels measurement (D)</p> Signup and view all the answers

    Which of the following is a therapeutic classification that helps glucose get into cells?

    <p>Insulin (B)</p> Signup and view all the answers

    Which therapeutic classification increases insulin production by the pancreas?

    <p>Sulfonylurea (C)</p> Signup and view all the answers

    Which therapeutic classification slows the digestion of complex carbohydrates?

    <p>Alpha-glucosidase inhibitor (A)</p> Signup and view all the answers

    Which therapeutic classification controls high blood sugar?

    <p>Biguanide (A)</p> Signup and view all the answers

    Which of the following therapeutic classifications is NOT used for diabetes management?

    <p>Antibiotics (D)</p> Signup and view all the answers

    Which of the following IS a type of insulin?

    <p>Combination Isophane/Regular Insulin (C)</p> Signup and view all the answers

    What does the combining form 'pancreat/o' refer to?

    <p>Pancreas (A)</p> Signup and view all the answers

    Which combining form represents the concept of glucose or sugar?

    <p>glyc/o (A)</p> Signup and view all the answers

    What does the combining form 'acr/o' indicate?

    <p>Extremities (B)</p> Signup and view all the answers

    The combining form 'hydr/o' is related to which substance?

    <p>Water (C)</p> Signup and view all the answers

    What is indicated by the combining form 'toxic/o'?

    <p>Poison (D)</p> Signup and view all the answers

    Which combining form refers to the concept of the adrenal gland?

    <p>adren/o (A)</p> Signup and view all the answers

    The combining form 'calc/o' relates to which of the following?

    <p>Calcium (C)</p> Signup and view all the answers

    What does the combining form 'natr/o' signify?

    <p>Sodium (A)</p> Signup and view all the answers

    Which gland is responsible for producing T lymphocytes required for the immune system?

    <p>Thymus gland (D)</p> Signup and view all the answers

    Which hormone is primarily secreted by the ovaries?

    <p>Estrogen (C)</p> Signup and view all the answers

    What condition is characterized by high blood sugar levels?

    <p>Hyperglycemia (B)</p> Signup and view all the answers

    What is the role of insulin in the body?

    <p>To lower blood sugar levels (C)</p> Signup and view all the answers

    What is the primary function of testes in the male reproductive system?

    <p>Secrete testosterone (A)</p> Signup and view all the answers

    What describes the negative feedback system in endocrine regulation?

    <p>A process that balances hormone levels by decreasing production when levels are high (D)</p> Signup and view all the answers

    Which function do the reproductive glands serve?

    <p>Produce sex hormones that influence reproductive functions (C)</p> Signup and view all the answers

    Which of the following best defines hypoglycemia?

    <p>Low blood sugar levels (C)</p> Signup and view all the answers

    What is the main function of the pituitary gland?

    <p>Secrete hormones that influence other glands (D)</p> Signup and view all the answers

    Which hormone is produced by the pineal gland?

    <p>Melatonin (A)</p> Signup and view all the answers

    What does the anterior lobe of the pituitary gland secrete?

    <p>Growth hormone, TSH, FSH, LH, prolactin, and ACTH (C)</p> Signup and view all the answers

    What role do the parathyroid glands play in the body?

    <p>Maintaining calcium and phosphorus levels in the blood (C)</p> Signup and view all the answers

    Which gland is primarily responsible for regulating the body's circadian rhythm?

    <p>Pineal gland (D)</p> Signup and view all the answers

    Which hormones are produced by the thyroid gland?

    <p>Thyroxine and triiodothyronine (D)</p> Signup and view all the answers

    Which of the following pairs hormones with their respective function?

    <p>Adrenocorticotropic hormone: stimulates adrenal glands (D)</p> Signup and view all the answers

    Which of the following correctly describes the adrenal glands?

    <p>Produce hormones related to stress response (A)</p> Signup and view all the answers

    Flashcards

    Endocrine vs Exocrine Glands

    Endocrine glands secrete hormones directly into the bloodstream, while exocrine glands release substances through ducts.

    Hormone

    A hormone is a chemical messenger produced by glands that regulates various body functions.

    Hyposecretion & Hypersecretion

    Hyposecretion is low hormone release, while hypersecretion is excess release, affecting body functions.

    Steroid vs Nonsteroid Hormones

    Steroid hormones pass through cell membranes to act inside cells; nonsteroid hormones bind to receptors on cell surfaces.

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    Feedback Mechanisms

    Negative feedback reduces hormone release, while positive feedback increases it, maintaining balance.

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    Antidiuretic hormone (ADH)

    Hormone that accelerates water reabsorption in kidneys, reducing urine secretion.

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    Oxytocin (OT)

    Hormone that stimulates uterine contractions and milk release in breastfeeding.

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    Hypothalamus role

    Produces ADH and oxytocin and controls their release via nervous stimulation.

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    Thyroid hormones (T3 & T4)

    hormones that accelerate metabolism and regulate the body's metabolic rate.

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    Calcitonin (CT)

    Hormone that decreases blood calcium levels by inhibiting bone breakdown.

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    Hyperthyroidism

    Condition of excess thyroid hormone leading to increased metabolic rate and symptoms like restlessness.

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    Hypothyroidism

    Condition of low thyroid hormone leading to a decreased metabolic rate, often causing fatigue and weight gain.

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    Goiter

    Painless enlargement of the thyroid often caused by iodine deficiency.

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    Anterior Pituitary Gland

    The front part of the pituitary gland that produces several important hormones.

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    Thyroid-stimulating hormone (TSH)

    A hormone that stimulates growth and activity of the thyroid gland.

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    Adrenocorticotropic hormone (ACTH)

    A hormone that stimulates the adrenal cortex to release glucocorticoids like cortisol.

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    Follicle-stimulating hormone (FSH)

    A hormone that initiates the growth of ovarian follicles in females.

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    Luteinizing hormone (LH)

    A hormone that triggers ovulation and stimulates progesterone secretion.

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    Growth hormone (GH)

    A hormone that promotes growth by increasing fat breakdown and protein synthesis.

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    Prolactin (PRL)

    A hormone that stimulates breast development and milk production.

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    Growth hormone abnormalities

    Conditions caused by irregular levels of growth hormone; includes gigantism and dwarfism.

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    Parathyroid hormone (PTH)

    Hormone that raises blood calcium levels through bone breakdown.

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    Adrenal cortex hormone types

    Includes glucocorticoids, mineralocorticoids, and sex hormones.

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    Function of glucocorticoids

    Maintain blood glucose levels and assist in blood pressure regulation.

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    Mineralocorticoids function

    Increase sodium and decrease potassium in blood by affecting kidneys.

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    Epinephrine (Epi)

    Hormone that intensifies sympathetic responses during stress.

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    Norepinephrine function

    Works with epinephrine to prolong sympathetic effects.

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    Cushing syndrome causes

    Result of hypersecretion of glucocorticoids leading to excess stress responses.

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    Addison disease

    Result of hyposecretion of adrenal hormones leading to fatigue and weakness.

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    Exocrine glands

    Glands that secrete products into ducts leading to surfaces or cavities.

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    Endocrine glands

    Ductless glands that secrete hormones directly into the bloodstream.

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    Target cells

    Cells that are affected by hormones, located in target organs.

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    Negative feedback

    A mechanism that reverses physiological changes to maintain homeostasis.

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    Hypersecretion

    The secretion of excess hormones by glands.

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    Steroid hormones

    Hormones that pass through cell membranes, binding to receptors in the nucleus and affecting DNA.

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    Prostaglandins

    Powerful substances that act locally in various tissues to influence body functions.

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    Glucagon

    Hormone secreted by alpha cells that increases blood glucose levels by stimulating glycogen breakdown.

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    Insulin

    Hormone secreted by beta cells that decreases blood glucose levels by promoting glucose uptake into cells.

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    Type 1 Diabetes

    Diabetes resulting from insufficient insulin production by the pancreas.

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    Type 2 Diabetes

    Diabetes due to the body's cells being resistant to insulin's effects, leading to high blood sugar.

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    Thymosin

    Hormone secreted by the thymus that is vital for immune system development and function.

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    Estrogen

    Hormone secreted by the ovaries that influences female sexual characteristics and reproduction.

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    Testosterone

    Hormone secreted by interstitial cells of testes that promotes male characteristics and reproductive functions.

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    Melatonin

    Hormone secreted by the pineal gland that regulates sleep-wake cycles and seasonal functions.

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    Ghrelin

    Hunger hormone secreted by the stomach lining that increases appetite.

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    Atrial Natriuretic Hormone (ANH)

    Hormone secreted by the heart that promotes sodium loss from the kidneys.

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    Radioactive Iodine Uptake

    A nuclear medicine test measuring iodine absorption in the thyroid.

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    Thyroid Function Reflection

    Evaluation of thyroid function by measuring TSH, T3, and T4 levels.

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    Biguanide

    Medication that lowers blood sugar levels by increasing insulin sensitivity.

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    Sulfonylurea

    Medications that stimulate the pancreas to produce more insulin.

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    Alpha-glucosidase Inhibitor

    Slows the digestion of carbohydrates to control blood sugar levels post-meals.

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    Insulin Replacement Therapy

    Treatment to provide insulin for those lacking it, such as in diabetes.

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    Pituitary Gland

    Structure attached to the hypothalamus; secretes several hormones.

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    Anterior Lobe

    Part of the pituitary gland secreting hormones like GH and TSH.

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    Posterior Lobe

    The portion of the pituitary gland that releases oxytocin and ADH.

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    Pineal Gland

    Located in the brain; produces melatonin for sleep regulation.

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    Circadian Rhythm

    Natural sleep-wake cycle regulated by light exposure.

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    Thyroid Gland

    Produces hormones like T3 and T4 that regulate metabolism.

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    Parathyroid Glands

    Small glands that regulate calcium and phosphorus levels in the blood.

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    Adrenal Glands

    Produce hormones for stress response, including adrenaline.

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    pancreat/o

    Combining form for pancreas.

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    gluc/o

    Combining form for glucose, sugar, or sweet.

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    acr/o

    Combining form for extremities.

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    hydr/o

    Combining form for water.

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    aden/o

    Combining form for gland.

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    glycos/o

    Combining form for glucose or sweet.

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    thyroid/o

    Combining form for thyroid gland.

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    toxic/o

    Combining form for toxic or poison.

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    Diabetes mellitus

    A pathology in which blood sugar levels may widely fluctuate.

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    Hyperglycemia

    A condition of high blood sugar.

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    Hypoglycemia

    A condition of low blood sugar.

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    Thymus gland

    Located above the heart, it plays a role in immunity and produces T lymphocytes.

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    Ovaries

    The primary sex organs in females that secrete estrogen and progesterone.

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    Testes

    Located in the scrotum, they secrete testosterone and contain seminiferous tubules.

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    Hyperaldosteronism

    Condition of excess aldosterone, causing hypertension and low potassium levels.

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    Hypoparathyroidism

    Condition of insufficient parathyroid hormone leading to low calcium levels in the blood.

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    Finger stick blood sugar (FSBS)

    Test measuring blood glucose levels from a fingertip prick.

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    Glycosylated hemoglobin (HbA1c)

    Average blood glucose level over the past 2-3 months, reported as a percentage.

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    Polydipsia

    Increased thirst, often due to high blood sugar or dehydration.

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    Polyuria

    Excessive urination, commonly associated with diabetes mellitus.

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    Pituitary dwarfism

    Condition of stunted growth caused by insufficient growth hormone during childhood.

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    Thyrotoxicosis

    Condition resulting from excessive thyroid hormones in the body, leading to increased metabolism.

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    Acromegaly

    A disorder caused by excess growth hormone, leading to enlarged bones.

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    Addison’s disease

    A condition caused by the underproduction of adrenal hormones, resulting in fatigue and weight loss.

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    Diabetes Insipidus

    A disorder characterized by extreme thirst and frequent urination due to ADH deficiency.

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    Cushing’s disease

    A disorder caused by excess cortisol, leading to symptoms like weight gain and skin changes.

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    Congenital Hypothyroidism

    A condition present at birth characterized by inadequate thyroid hormone production.

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    Graves’ disease

    An autoimmune disorder that causes hyperthyroidism, leading to symptoms like tremors and bulging eyes.

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    Diabetic Ketoacidosis

    A serious complication of diabetes characterized by high levels of ketones due to lack of insulin.

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    Study Notes

    Endocrine System Overview

    • Exocrine glands are not part of the endocrine system. They secrete their products into ducts leading to surfaces or cavities.
    • Endocrine glands are ductless. They secrete hormones, chemical substances that regulate target cells and organs.

    Learning Objectives - Lesson 12.1: Hormones

    • Differentiate between endocrine and exocrine glands.
    • Define the term "hormone".
    • Identify and describe the principal functions of major endocrine hormones and related conditions (hyposecretion or hypersecretion).
    • Describe the mechanisms of steroid and non-steroid hormone action.
    • Explain how negative and positive feedback mechanisms regulate hormone secretion.
    • Explain the primary mechanisms of endocrine conditions.
    • Define and explain the importance of prostaglandins.

    Learning Objectives - Lesson 12.2: The Endocrine Glands

    • Identify and locate primary endocrine glands.
    • List the major hormones produced by each gland.
    • Identify endocrine system disorders.

    Location of Endocrine Glands

    • The endocrine glands and their locations are depicted in a diagram. (specific locations are not included here).

    Mechanisms of Hormone Action

    • Endocrine glands secrete hormones into the blood.
    • Hormones carry out communication and control activities, but in a slower, longer-lasting manner compared to nerve impulses.
    • Target cells, within target organs, are affected by hormones.

    Nonsteroid and Steroid Hormones

    • Nonsteroid hormones, acting as first messengers, bind to receptors on the target cell membrane to initiate second messengers that control cell activities.
    • Steroid hormones bind to receptors inside the cell nucleus and impact cell activity by interacting with DNA.

    Mechanism of Protein Hormone Action

    • A diagram illustrates the mechanism.

    Mechanism of Steroid Hormone Action

    • A diagram displays the mechanism.

    Regulation of Hormone Secretion

    • Hormone secretion is controlled by homeostatic feedback.
    • Negative feedback mechanisms reverse changes in physiological systems.
    • Positive feedback, uncommon, amplifies physiological changes.

    Negative Feedback

    • A diagram illustrates the negative feedback loop involving glucose regulation.

    Mechanisms of Endocrine Disease

    • Hypersecretion is the secretion of excess hormone.
    • Hyposecretion is insufficient hormone secretion.
    • Polyendocrine disorders involve hyper or hyposecretion of more than one hormone.
    • Target cell insensitivity produces effects similar to hyposecretion.
    • Endocrine specialists use various treatments (surgery and hormone therapy).

    Prostaglandins

    • Prostaglandins (PGs) are powerful substances present in numerous body tissues.
    • PGs are locally produced and diffuse short distances to act on cells.
    • Classes of PGs include PGA, PGE, and PGF.
    • PGs impact many body functions (e.g., respiration, blood pressure, gastrointestinal secretions).

    Pituitary Gland

    • Two major parts of the pituitary gland are detailed: anterior (adenohypophysis) and posterior (neurohypophysis).

    Anterior Pituitary Gland

    • List the major hormones produced by anterior pituitary gland such as Thyroid-stimulating hormone (TSH), Adrenocorticotropic hormone (ACTH), Follicle-stimulating hormone (FSH), Luteinizing hormone (LH), Growth hormone (GH), and Prolactin (lactogenic hormone).

    Functions of Major Hormones (Anterior Pituitary Gland)

    • TSH: Promotes thyroid growth & secretion.
    • ACTH: Promotes adrenal cortex growth & secretion of glucocorticoids (e.g., cortisol).
    • FSH: Stimulates ovarian follicle growth and readiness to release eggs.
    • LH: Works with FSH to secrete estrogen and control ovulation; stimulates progesterone secretion.
    • GH: Promotes protein synthesis to facilitate growth; increases blood glucose.
    • Prolactin: Motivates breast development & milk production.

    Functions of Major Hormones (Posterior Pituitary Gland)

    • ADH: Reinforces water retention by accelerating water reabsorption into the blood.
    • OT: Triggers uterine contractions during childbirth and milk release from mammary glands.

    Thyroid Gland

    • Names of thyroid hormones: Thyroxine (T4) and triiodothyronine (T3).
    • Function of thyroid hormones: Increase metabolic rate.
    • Calcitonin decreases blood calcium by inhibiting bone breakdown.

    Thyroid and Parathyroid Glands

    • A diagram illustrates the location of the thyroid and parathyroid glands.

    Hyperthyroidism

    • Excessive thyroid hormone secretion causes increased metabolic rate, restlessness, and protruding eyes (exophthalmos). A condition called Graves' disease is an inherited form of hyperthyroidism.

    Hypothyroidism

    • Insufficient thyroid hormone secretion, associated with goiter (enlarged thyroid) due to iodine deficiency. Other causes can also lead to hypothyroidism, which can result in condition(s) such as cretinism (infancy) or myxedema (adulthood).

    Parathyroid Glands

    The parathyroid hormone (PTH) increases blood calcium concentration by encouraging bone breakdown to release calcium into the blood.

    Regulation of Blood Calcium Levels

    • A diagram illustrates the regulation of blood calcium.

    Adrenal Glands: Adrenal Cortex

    • Names of hormones secreted by the adrenal cortex: glucocorticoids (cortisol), mineralocorticoids (aldosterone), and sex hormones (androgens).
    • Three zones of the adrenal cortex: outer zone (mineralocorticoids), middle zone (glucocorticoids), and inner zone (sex hormones).
    • Mineralocorticoids increase blood sodium and decrease potassium (regulate electrolyte balance).

    Functions of Glucocorticoids

    • Maintain normal blood glucose by increasing gluconeogenesis.
    • Contribute to maintaining normal blood pressure.
    • Involved in anti-inflammatory, anti-immunity, and anti-allergy effects.
    • Release is rapid during stress. High levels cause other stress responses.

    Glucocorticoid Stress Responses

    • A diagram details the glucocorticoid response to stress, showing effects on proteins, fats, immunity, recovery from inflammation, and metabolic processes in response to increased glucocorticoid levels.

    Adrenal Medulla

    • Hormones: Epinephrine, Norepinephrine
    • Function: Intensifying and prolonging sympathetic nervous system effects.

    Adrenal Conditions

    • Hypersecretion of glucocorticoids leads to Cushing syndrome.
    • Hypersecretion of adrenal androgens may lead to virilization in females.
    • Hyposecretion of cortical hormones leads to Addison disease.

    Cushing Syndrome

    • A diagram illustrates features of Cushing syndrome.

    Pancreatic Islets

    • Glucose regulation hormones secreted by the pancreatic islets: Glucagon (alpha cells) and Insulin (beta cells).
    • Glucagon increases blood glucose by stimulating glycogenolysis.
    • Insulin decreases blood glucose by promoting glucose uptake into cells.

    Function of Hormones (Insulin)

    • Insulin decreases blood glucose by promoting glucose absorption into cells.

    Diabetes Mellitus

    • Type 1: Hyposecretion of insulin.
    • Type 2: Target cell insensitivity to insulin.
    • Both types result in insufficient glucose uptake from blood into cells, leading to elevated blood glucose (hyperglycemia) and glucose in the urine (glycosuria).

    Diabetes Mellitus (cont.)

    • A diagram displays the underlying mechanisms of the two types of diabetes.

    Female Sex Glands

    • Ovarian follicles and the corpus luteum produce female sex hormones.
    • Estrogen effects: Promotes breast and genital development; regulates body contours in females; initiates the menstrual cycle.

    Male Sex Glands

    • Interstitial cells of the testes secrete testosterone.
    • Testosterone effects: Promotes external genital development; affects voice changes; contributes to the body contours of males.

    Thymus

    • Hormone: Thymosin.
    • Function: Promotes immune system development.

    Placenta

    • Hormones produced by the placenta: Chorionic gonadotropins, estrogens, and progesterone.
    • Function of Placental hormones: Maintains corpus luteum to ensure appropriate hormone levels during pregnancy.

    Pineal Gland

    • A small gland located near the third ventricle of the brain.
    • Its influence on secretory activities is related to the amount of light. Major hormone: melatonin.
    • Melatonin regulates the body's internal clock. Seasonal Affective Disorder (SAD) can be a result of abnormal melatonin.

    Other Endocrine Structures

    • Numerous organs (e.g., stomach, intestines, and kidneys) produce endocrine hormones.
    • Ghrelin increases appetite and lowers metabolism.
    • The heart's atrial wall secretes ANH (atrial natriuretic hormone) to encourage excretion of sodium.
    • Leptin is secreted by fat cells and controls feelings of fullness.

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    Description

    Test your knowledge of the endocrine system with this quiz covering hormone functions, gland types, and feedback mechanisms. Questions explore the roles of various hormones and conditions related to hormone secretion. Perfect for students studying human biology or physiology.

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