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Questions and Answers
What is the primary cause of Cushing syndrome?
What is the primary cause of Cushing syndrome?
- Hypersecretion of glucocorticoids in the adrenal gland (correct)
- Hyposecretion of glucocorticoids
- Hypersecretion of CRH in the hypothalamus
- Hyposecretion of ACTH in the pituitary gland
What is the effect of glucocorticoid hypersecretion on collagen fibers in the subcutaneous tissue?
What is the effect of glucocorticoid hypersecretion on collagen fibers in the subcutaneous tissue?
- Altered collagen fibers leading to skin pigmentation
- Decreased collagen fibers leading to fragile skin (correct)
- No effect on collagen fibers
- Increased collagen fibers leading to thicker skin
What is the result of protein loss from muscles in Cushing syndrome?
What is the result of protein loss from muscles in Cushing syndrome?
- Gain of muscle mass and mild weakness
- Gain of muscle mass and strength
- No change in muscle mass or strength
- Loss of muscle mass and severe weakness (correct)
What is the characteristic distribution of fat in Cushing syndrome?
What is the characteristic distribution of fat in Cushing syndrome?
What is the effect of glucocorticoid hypersecretion on blood glucose concentration?
What is the effect of glucocorticoid hypersecretion on blood glucose concentration?
What is the effect of glucocorticoid hypersecretion on tissue proteins?
What is the effect of glucocorticoid hypersecretion on tissue proteins?
What is the consequence of high blood glucose on beta cells of Langerhans?
What is the consequence of high blood glucose on beta cells of Langerhans?
What is the reason for hypertension in 80% of patients with Cushing syndrome?
What is the reason for hypertension in 80% of patients with Cushing syndrome?
Which of the following is a characteristic of Cushing syndrome?
Which of the following is a characteristic of Cushing syndrome?
What type of Cushing syndrome arises from abnormalities in the adrenal glands themselves?
What type of Cushing syndrome arises from abnormalities in the adrenal glands themselves?
What is the reason for muscle weakness and thin limbs in Cushing disease?
What is the reason for muscle weakness and thin limbs in Cushing disease?
What is a complication of Cushing disease that can delay healing of wounds?
What is a complication of Cushing disease that can delay healing of wounds?
What is the consequence of Addison's disease on blood sugar levels between meals?
What is the consequence of Addison's disease on blood sugar levels between meals?
What is the effect of cortisol deficiency on protein and fat mobilization in Addison's disease?
What is the effect of cortisol deficiency on protein and fat mobilization in Addison's disease?
What is the characteristic skin pigmentation pattern in Addison's disease?
What is the characteristic skin pigmentation pattern in Addison's disease?
What is the primary cause of melanin deposition in Addison's disease?
What is the primary cause of melanin deposition in Addison's disease?
What is the association between Addison's disease and blood pressure?
What is the association between Addison's disease and blood pressure?
What is the consequence of mineralocorticoids deficiency in Addison's disease?
What is the consequence of mineralocorticoids deficiency in Addison's disease?
What is the primary function of androgens?
What is the primary function of androgens?
What is the main source of androgenic activity in males?
What is the main source of androgenic activity in males?
What stimulates the secretion of adrenal androgens?
What stimulates the secretion of adrenal androgens?
What is the most likely diagnosis for a female with excessive facial hair and a deepened voice?
What is the most likely diagnosis for a female with excessive facial hair and a deepened voice?
What is the likely cause of rapid development of male sexual organs and virilization in a prepubertal boy?
What is the likely cause of rapid development of male sexual organs and virilization in a prepubertal boy?
Why is diagnosing AGS in adult males challenging?
Why is diagnosing AGS in adult males challenging?
What can be a life-threatening consequence for a person with Addison's disease experiencing a minor infection?
What can be a life-threatening consequence for a person with Addison's disease experiencing a minor infection?
What causes the darkening of the skin and mucous membranes in Addison's disease?
What causes the darkening of the skin and mucous membranes in Addison's disease?
What is Addison's disease primarily a deficiency of?
What is Addison's disease primarily a deficiency of?
What is often associated with a deficiency of in Addison's disease?
What is often associated with a deficiency of in Addison's disease?
What is the characteristic of primary Addison's disease?
What is the characteristic of primary Addison's disease?
Why is hyponatremia common in Addison's disease?
Why is hyponatremia common in Addison's disease?
