Endocrine and Reproductive Systems: Exam Prep

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Questions and Answers

Which characteristic distinguishes the endocrine system from the nervous system?

  • The endocrine system's effects are typically faster and shorter-lived than those of the nervous system.
  • The endocrine system uses electrical signals for communication, while the nervous system relies on chemical messengers.
  • The endocrine system uses chemical messengers that result in slower but more sustained effects. (correct)
  • The endocrine system influences only a limited number of target cells, unlike the widespread effects of the nervous system.

A researcher is studying a new hormone that binds to receptors on the cell surface. Based on this information, to which class does this hormone likely belong?

  • Steroid hormones
  • Thyroid Hormones
  • Peptide/Protein Hormones (correct)
  • Amine Hormones

A patient is diagnosed with a tumor that causes excessive secretion of GHRH. Which of the following is the most likely consequence of this condition?

  • Decreased secretion of growth hormone (GH).
  • Increased release of thyroid-stimulating hormone (TSH).
  • Suppressed production of cortisol.
  • Elevated levels of growth hormone (GH). (correct)

Following childbirth, a new mother is having difficulty with milk production. Which hormone is most likely deficient?

<p>Prolactin (B)</p> Signup and view all the answers

A patient presents with symptoms of dehydration and low blood pressure. A doctor suspects a hormonal imbalance. Which hormone should the doctor measure?

<p>Antidiuretic hormone (ADH) (A)</p> Signup and view all the answers

A person is experiencing increased bone density due to increased calcium deposition. Which hormone is directly associated with this condition?

<p>Calcitonin (D)</p> Signup and view all the answers

A woman is experiencing irregular menstrual cycles and difficulties conceiving. Which of the following hormones might be involved in these issues?

<p>Either Follicle-Stimulating Hormone (FSH) or Luteinizing Hormone (LH) (D)</p> Signup and view all the answers

If the hypothalamus is not producing enough TRH, which of the following hormonal imbalances would you expect to see?

<p>Decreased levels of TSH, T3, and T4. (D)</p> Signup and view all the answers

Which of the following accurately describes the mechanism by which parathyroid hormone (PTH) increases blood calcium levels?

<p>Stimulating osteoclast activity and promoting vitamin D activation. (B)</p> Signup and view all the answers

In a scenario where a patient's blood glucose levels are dangerously high, which hormone would the pancreas typically release to counteract this condition?

<p>Insulin, to promote glucose uptake into cells. (C)</p> Signup and view all the answers

During a stressful situation, the adrenal cortex releases cortisol. What are the primary effects of cortisol release?

<p>Managing stress, increasing glucose availability, and suppressing the immune system. (C)</p> Signup and view all the answers

Which of the following correctly pairs a G protein-coupled receptor (GPCR) pathway with its downstream effectors?

<p>Gs → Activates cAMP → Protein Kinase A (PKA). (A)</p> Signup and view all the answers

A patient presents with low blood pressure. How does the Renin-Angiotensin-Aldosterone System (RAAS) work to restore blood pressure?

<p>Stimulating renin release, converting angiotensinogen to angiotensin I, then angiotensin II, leading to aldosterone release and water retention. (C)</p> Signup and view all the answers

Which of the following is the correct sequence of structures through which sperm pass from production to ejaculation?

<p>Seminiferous Tubules → Epididymis → Vas Deferens → Ejaculatory Duct → Urethra. (A)</p> Signup and view all the answers

During the female ovarian cycle, what hormonal event triggers ovulation?

<p>A surge in luteinizing hormone (LH) levels. (B)</p> Signup and view all the answers

Which of the following best describes the role of the prostate gland in the male reproductive system?

<p>Producing an alkaline fluid to enhance sperm motility. (D)</p> Signup and view all the answers

A woman is experiencing heavy menstrual bleeding due to a thickened endometrial lining. Which phase of the uterine cycle is she most likely in, and which hormone is primarily responsible for this condition?

<p>Proliferative Phase; Estrogen. (C)</p> Signup and view all the answers

Considering the mnemonic 'FLAT PiG' for anterior pituitary hormones, which hormone is responsible for stimulating the adrenal cortex?

<p>Adrenocorticotropic Hormone (ACTH). (C)</p> Signup and view all the answers

Flashcards

Endocrine System

Regulates metabolism, growth, homeostasis, and reproduction by secreting hormones into the bloodstream.

Peptide/Protein Hormones

Water-soluble hormones that bind to surface receptors.

Steroid Hormones

Lipid-soluble hormones that pass through membranes to bind nuclear receptors.

Amine Hormones

Hormones derived from amino acids.

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GnRH (Gonadotropin-Releasing Hormone)

Stimulates FSH & LH release.

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FSH (Follicle-Stimulating Hormone)

Stimulates sperm & egg production.

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LH (Luteinizing Hormone)

Triggers ovulation & testosterone production.

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ADH (Vasopressin)

Promotes water retention in kidneys.

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Parathyroid Hormone (PTH)

Raises blood calcium by stimulating osteoclasts and activating vitamin D.

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Insulin

Lowers blood glucose by increasing glucose uptake into cells.

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Glucagon

Raises blood glucose by promoting glycogen breakdown.

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Aldosterone

Increases sodium and water retention to raise blood pressure.

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Cortisol

Manages stress, increases glucose, and suppresses the immune system.

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Negative Feedback

Most hormones use this mechanism; high hormone levels inhibit further secretion.

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Positive Feedback

Rare; hormone release causes more hormone release (e.g., oxytocin in labor).

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FSH in Males

Stimulates Sertoli cells, which are responsible for spermatogenesis.

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Follicular Phase

Outer layer of follicles develops; estrogen rises.

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Sperm Pathway

Includes: Seminiferous Tubules, Epididymis, Vas Deferens, Ejaculatory Duct, Urethra, Penis.

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Study Notes

  • Focus is on the endocrine and reproductive systems, for exam preparation
  • Includes hormone functions, reproductive anatomy, feedback loops, and key physiological processes

Endocrine System Overview

  • The endocrine system regulates metabolism, growth, homeostasis, and reproduction
  • Regulation occurs by secreting hormones into the bloodstream
  • Unlike the fast electrical signals of the nervous system, the endocrine system uses slow but long-lasting chemical messengers
  • Glands like the pituitary, thyroid, adrenal glands, pancreas, and gonads produce hormones

Key Hormone Classes

  • Peptide/Protein Hormones: Water-soluble, bind to surface receptors (e.g., insulin, glucagon)
  • Steroid Hormones: Lipid-soluble, pass through membranes to bind nuclear receptors (e.g., cortisol, testosterone)
  • Amine Hormones: Derived from amino acids (e.g., epinephrine, norepinephrine, dopamine)

Major Hormones and Their Functions

  • Includes the location of production

Hypothalamus & Pituitary Gland (Master Glands)

  • GnRH (Gonadotropin-Releasing Hormone): Stimulates FSH & LH release
  • TRH (Thyrotropin-Releasing Hormone): Stimulates TSH release
  • CRH (Corticotropin-Releasing Hormone): Stimulates ACTH release
  • GHRH (Growth Hormone-Releasing Hormone): Stimulates GH release

Anterior Pituitary Hormones

  • Mnemonic: FLAT PiG
  • FSH (Follicle-Stimulating Hormone): Stimulates sperm & egg production
  • LH (Luteinizing Hormone): Triggers ovulation & testosterone production
  • ACTH (Adrenocorticotropic Hormone): Stimulates cortisol release
  • TSH (Thyroid-Stimulating Hormone): Stimulates T3 & T4 secretion
  • Prolactin: Promotes milk production
  • Growth Hormone: Stimulates cell growth, metabolism, and IGF-1 release

Posterior Pituitary Hormones

  • Oxytocin: Stimulates uterine contractions & milk ejection
  • ADH (Vasopressin): Promotes water retention in kidneys

Thyroid & Parathyroid Glands

  • T3 & T4: Regulate metabolism, energy production, and body temperature
  • Calcitonin: Lowers blood calcium by inhibiting osteoclasts
  • Parathyroid Hormone (PTH): Raises blood calcium by stimulating osteoclasts & vitamin D activation

Pancreas (Blood Sugar Regulation)

  • Insulin: Lowers blood glucose by increasing uptake into cells
  • Glucagon: Raises blood glucose by promoting glycogen breakdown

Adrenal Glands

  • Cortex:
    • Aldosterone: Increases sodium & water retention to raise blood pressure
    • Cortisol: Manages stress, increases glucose, and suppresses the immune system
    • Androgens: Precursor hormones for testosterone and estrogen
  • Medulla:
    • Epinephrine & Norepinephrine: Fight-or-flight response, increases heart rate and alertness

Hormonal Regulation & Feedback Loops

  • Hormone secretion is tightly regulated through feedback mechanisms
  • Negative Feedback: Most hormones use this mechanism (e.g., high cortisol inhibits ACTH)
  • Positive Feedback: Rare, but occurs in labor (oxytocin) and lactation (prolactin)

GPCR Pathways

  • Gs → Activates cAMP → Protein Kinase A (PKA)
  • Gq → Activates phospholipase C → IP3 & DAG → Calcium release

Renin-Angiotensin-Aldosterone System (RAAS)

  • Renin is released by the kidneys due to low blood pressure
  • Renin converts angiotensinogen to angiotensin I
  • ACE converts angiotensin I to angiotensin II
  • Angiotensin II stimulates aldosterone release, causing sodium & water retention

Reproductive System Overview

Male Reproductive System

  • Spermatogenesis occurs in seminiferous tubules, sperm matures in the epididymis
  • Path of Sperm: Seminiferous Tubules → Epididymis → Vas Deferens → Ejaculatory Duct → Urethra
  • Hormonal Regulation:
    • GnRH stimulates FSH & LH
    • FSH stimulates Sertoli cells (spermatogenesis)
    • LH stimulates Leydig cells (testosterone production)

Accessory Glands

  • Seminal Vesicles: Secrete fructose-rich fluid
  • Prostate Gland: Produces alkaline fluid for sperm motility
  • Bulbourethral Glands: Secrete lubricating mucus

Female Reproductive System

  • Oogenesis: Primary oocytes arrest in prophase I until puberty

Ovarian Cycle Phases

  • Follicular Phase: Follicles grow, estrogen rises
  • Ovulation: LH surge causes egg release
  • Luteal Phase: Corpus luteum secretes progesterone

Uterine Cycle Phases

  • Menstrual Phase: Shedding of the endometrium
  • Proliferative Phase: Estrogen causes endometrial thickening
  • Secretory Phase: Progesterone maintains the lining for potential pregnancy

Key Mnemonics

  • FLAT PiG = Anterior Pituitary Hormones (FSH, LH, ACTH, TSH, Prolactin, GH)
  • RAAS: Remember R-A-A → Renin → Angiotensin → Aldosterone
  • Sperm Pathway: SEVEn UP = Seminiferous Tubules, Epididymis, Vas Deferens, Ejaculatory Duct, Urethra, Penis

Active Recall & Study Strategies

  • Quiz Yourself: Use flashcards for hormone functions & feedback loops
  • Draw Diagrams: Recreate the RAAS system, ovarian cycle, and sperm pathway
  • Teach Someone Else: Explaining solidifies understanding

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