Endocrine System: Neurohormonal Control of Reproductive Hormones
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Questions and Answers

What is the primary function of the Fallopian tubes in the female reproductive system?

  • To transport eggs from the ovaries to the uterus (correct)
  • To nurture the fetus
  • To dilate for birthing
  • To synthesize hormones
  • Which hormone is primarily responsible for maintaining pregnancy in the female reproductive system?

  • Oestrogen
  • Progesterone (correct)
  • Chorionic gonadotropin
  • Androgen
  • What is the name of the axis that regulates the reproductive system in both males and females?

  • Hypothalamic-Pituitary-Pancreatic Axis
  • Hypothalamic-Pituitary-Gonadal Axis (correct)
  • Hypothalamic-Pituitary-Adrenal Axis
  • Hypothalamic-Pituitary-Thyroid Axis
  • What is the main source of chorionic gonadotropin (hCG)?

    <p>Placental chorion</p> Signup and view all the answers

    What is the primary function of the cervix in the female reproductive system?

    <p>To dilate for birthing</p> Signup and view all the answers

    Which of the following is NOT a steroid hormone involved in the reproductive system?

    <p>Chorionic gonadotropin</p> Signup and view all the answers

    What is the primary purpose of GnRH agonist in IVF treatment?

    <p>To shut off gonadotropin secretion</p> Signup and view all the answers

    What is the typical duration of FSH injection in IVF treatment?

    <p>10 days</p> Signup and view all the answers

    What is the primary cause of osteoporosis in menopausal women?

    <p>↓ circulating oestrogen</p> Signup and view all the answers

    What is the benefit of tibolone tablets in HRT?

    <p>Can be used continuously without cyclical progesterone</p> Signup and view all the answers

    What is the adverse effect of unopposed oestrogen in HRT?

    <p>↑ Risk of endometrial cancer</p> Signup and view all the answers

    Why does progesterone reduce the risk of cancer in HRT?

    <p>It counteracts the oestrogenic effect on the endometrium</p> Signup and view all the answers

    What is the primary function of DHT in target cells?

    <p>Inducing gene expression to stimulate proliferation and inhibit apoptosis</p> Signup and view all the answers

    Which of the following is NOT a metabolic effect of androgens?

    <p>Stimulating spermatogenesis</p> Signup and view all the answers

    What is the enzyme responsible for converting testosterone to DHT in peripheral tissues?

    <p>5α-reductase</p> Signup and view all the answers

    What is the main source of circulating testosterone?

    <p>Gonads (ovaries, testes, adrenal cortex)</p> Signup and view all the answers

    What is the effect of high levels of testosterone on libido?

    <p>Stimulates libido</p> Signup and view all the answers

    What is the ultimate effect of androgens on epiphyseal plates?

    <p>Fusion of epiphyseal plates</p> Signup and view all the answers

    What is the effect of very obese men converting their testosterone to oestrogen?

    <p>Feminizing effects</p> Signup and view all the answers

    What is the role of Inhibin in the Hypothalamo-Pituitary-Testicular axis?

    <p>Inhibits FSH release</p> Signup and view all the answers

    What is the cause of 3° hypogonadism?

    <p>Hypothalamic failure to secrete GnRH</p> Signup and view all the answers

    What is the typical karyotype of Klinefelter's syndrome?

    <p>XXY</p> Signup and view all the answers

    What is the effect of androgen insensitivity or resistance?

    <p>Partial or complete inability of cells to respond to androgens</p> Signup and view all the answers

    What is the approximate frequency of androgen insensitivity or resistance in XY births?

    <p>1 in 20,000 to 64,000</p> Signup and view all the answers

    What is the primary reason for abusing tetrahydrogestrinone, stanozolol, and nandrolone?

    <p>To improve muscle mass and endurance</p> Signup and view all the answers

    What is the mechanism of action of Abiraterone acetate?

    <p>Inhibiting the biosynthesis of androgens</p> Signup and view all the answers

    Which of the following is a side effect of using Finasteride?

    <p>Hair re-growth</p> Signup and view all the answers

    What is the difference between Finasteride and Dutasteride?

    <p>Finasteride is a type II inhibitor, while Dutasteride is a type I and II inhibitor</p> Signup and view all the answers

    What is the effect of 5α-reductase inhibitors on hair follicles?

    <p>Decrease the proportion of DHT</p> Signup and view all the answers

    What is the primary use of Anastrozole?

    <p>Treating breast cancer in postmenopausal women</p> Signup and view all the answers

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