Emulsification and HLB Calculations Quiz
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Questions and Answers

What is the required HLB for emulsifying soybean oil?

  • 8
  • 7 (correct)
  • 6
  • 9

    • What is the correct calculation for the required HLB of the oil phase in the lotion described?

  • 10.5
  • 9.9
  • 10.9 (correct)
  • 11.5

    • If the fraction of mineral oil in the oil phase is 0.86, what is the contribution of mineral oil to the required HLB calculation?

  • 8.5
  • 11.1
  • 9.03 (correct)
  • 10.5

    • What HLB value is assigned to Tween 40?

    <p>15.6</p> Signup and view all the answers

    What is the HLB value of glyceryl monostearate?

    <p>3.8</p> Signup and view all the answers

    What is the primary characteristic of an oral pharmaceutical emulsion?

    <p>It is always o/w.</p> Signup and view all the answers

    Which of the following represents a solid emulsion?

    <p>Ointment</p> Signup and view all the answers

    In the context of disperse systems, what type of dispersion medium is used in a solid foam?

    <p>Gas</p> Signup and view all the answers

    What is an example of a liquid aerosol?

    <p>Fogs and mists</p> Signup and view all the answers

    Which of the following systems has a liquid dispersed phase and a solid dispersion medium?

    <p>Sol suspension</p> Signup and view all the answers

    What is a key attribute of a surfactant solution in terms of foam formation?

    <p>It is capable of forming gas in liquid.</p> Signup and view all the answers

    Which of the following examples pertains to a solid aerosol?

    <p>Smoke</p> Signup and view all the answers

    What type of disperse system would you find in a product like a lotion?

    <p>Liquid emulsion</p> Signup and view all the answers

    What must emulsifiers used in parenteral formulations ensure?

    <p>Are non-toxic and prevent embolism</p> Signup and view all the answers

    What is the average droplet size for emulsions used in topical applications?

    <p>1 µm</p> Signup and view all the answers

    Which of the following is NOT a group classified for emulsifier selection?

    <p>Synthetic polymers</p> Signup and view all the answers

    Which factor is least important when formulating emulsions?

    <p>Personal preference of the formulator</p> Signup and view all the answers

    What is the Gibbs free energy change related to in emulsion formation?

    <p>Surface area and surface tension</p> Signup and view all the answers

    When is it crucial to sterilize emulsions?

    <p>For parenteral formulations</p> Signup and view all the answers

    Which oil property is NOT a consideration for emulsion formulation?

    <p>Taste and smell of the oil</p> Signup and view all the answers

    What happens to the possibility of collisions when surfactants are present?

    <p>It decreases due to reduced surface tension</p> Signup and view all the answers

    Which of the following is a hydrophilic colloid used as an emulsifier?

    <p>Methylcellulose</p> Signup and view all the answers

    What is a critical requirement for topical emulsions compared to parenteral emulsions?

    <p>Droplet size is less critical</p> Signup and view all the answers

    What does the HLB system primarily help to select?

    <p>The appropriate emulsifier for stable emulsions</p> Signup and view all the answers

    What HLB range is typically associated with oil-in-water (o/w) emulsifying agents?

    <p>8-18</p> Signup and view all the answers

    Which of the following surfactants has the highest HLB value?

    <p>Polysorbate 20 (Tween 20)</p> Signup and view all the answers

    Which HLB range is likely to be used for anti-foaming agents?

    <p>0-3</p> Signup and view all the answers

    Why is the HLB system limited to non-ionic surfactants?

    <p>The size and strength balance is irrelevant for ionic surfactants</p> Signup and view all the answers

    What does RHLB stand for in the context of the HLB system?

    <p>Required Hydrophile-Lipophile Balance</p> Signup and view all the answers

    Which surfactant has an HLB value closest to 4.7?

    <p>Sorbitan monostearate (Span 60)</p> Signup and view all the answers

    What kind of agents fall under the HLB range of 7-9?

    <p>Wetting and spreading agents</p> Signup and view all the answers

    What is the HLB value of Tween 60?

    <p>14.9</p> Signup and view all the answers

    Which of the following is NOT a fixed oil mentioned in the content?

    <p>Petroleum oil</p> Signup and view all the answers

    What is the calculated Required HLB of the oil phase in the lotion preparation?

    <p>10.9</p> Signup and view all the answers

    If the required HLB for the oil phase is determined to be 11, what is the HLB range for the emulsifiers to be used?

    <p>10 to 12</p> Signup and view all the answers

    What is the HLB of Lanolin (Anhydrous) used in the oil phase?

    <p>10</p> Signup and view all the answers

    Which of the following emulsifiers should be blended to achieve a required HLB of 11, given their HLB values?

    <p>Tween 40 and Glyceryl Monostearate</p> Signup and view all the answers

    What is the contribution of Mineral Oil to the required HLB calculation based on its fraction in the oil phase?

    <p>9.03</p> Signup and view all the answers

    Which type of disperse system contains a liquid dispersed phase and a liquid dispersion medium?

    <p>Emulsion</p> Signup and view all the answers

    What is an example of a solid emulsion?

    <p>Ointment</p> Signup and view all the answers

    Which disperse system is classified as having a gas dispersed phase and a solid dispersion medium?

    <p>Solid foam</p> Signup and view all the answers

    In the context of pharmaceutical emulsions, what is the typical type for oral consumption?

    <p>o/w</p> Signup and view all the answers

    Which of the following examples would classify as a liquid aerosol?

    <p>Mists</p> Signup and view all the answers

    What type of disperse system utilizes a solid as the dispersed phase and a gas as the dispersion medium?

    <p>Solid aerosol</p> Signup and view all the answers

    Which characteristic is unique to pharmaceutical emulsions intended for oral use?

    <p>They are always o/w emulsions.</p> Signup and view all the answers

    What is an example of a solid dispersed phase in a liquid suspension?

    <p>Aluminium hydroxide</p> Signup and view all the answers

    What is the primary purpose of surfactants in emulsion formation?

    <p>To reduce interfacial tension</p> Signup and view all the answers

    What is a characteristic of parenteral emulsions compared to topical emulsions?

    <p>They must always be sterile</p> Signup and view all the answers

    Which of the following classified groups is NOT a type of emulsifier?

    <p>Hydrophobic agents</p> Signup and view all the answers

    Why is the selection of emulsifiers very limited for parenteral formulations?

    <p>They must not cause toxicity or embolism</p> Signup and view all the answers

    Which droplet size is typical for emulsions used in topical applications?

    <p>1 µm</p> Signup and view all the answers

    What role do emulsifying agents play in minimizing globule coalescence?

    <p>They reduce interfacial tension</p> Signup and view all the answers

    What is a common property that formulators must consider regarding oil phases in emulsions?

    <p>Oil must be non-toxic</p> Signup and view all the answers

    What happens to Gibbs free energy ($ΔG^*$) when surfactants are introduced at the oil-water interface?

    <p>$ΔG^*$ decreases</p> Signup and view all the answers

    What is the average droplet size maintained in parenteral emulsions?

    <p>0.2 µm</p> Signup and view all the answers

    Which type of emulsifier is methylcellulose classified under?

    <p>Hydrophilic colloids</p> Signup and view all the answers

    What does the HLB system primarily measure in surfactant molecules?

    <p>The balance of hydrophilic and lipophilic properties</p> Signup and view all the answers

    Which of the following HLB ranges is typically associated with oil-in-water (o/w) emulsifying agents?

    <p>8-18</p> Signup and view all the answers

    What role do surfactants with an HLB of 15-20 play in formulations?

    <p>Solubilizers</p> Signup and view all the answers

    What is the significance of the Required HLB (RHLB) in emulsification?

    <p>It specifies the ideal HLB value for fats and oils.</p> Signup and view all the answers

    Which of the following substances would have the lowest HLB value based on the chart provided?

    <p>Sorbitan trioleate</p> Signup and view all the answers

    In the HLB system, what is the primary function of emulsifiers with an HLB range of 3-6?

    <p>W/o emulsifying agents</p> Signup and view all the answers

    Which fixed oil is listed in the content as an example?

    <p>Olive oil</p> Signup and view all the answers

    Which of the following surfactants has an HLB value closest to 15?

    <p>Polysorbate 60</p> Signup and view all the answers

    Why is the HLB system important for non-ionic surfactants specifically?

    <p>It helps in selecting stable emulsifiers.</p> Signup and view all the answers

    What does an HLB value of 7-9 indicate about a surfactant's function?

    <p>Wetting and spreading agent</p> Signup and view all the answers

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