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Questions and Answers
How is the HLB value of an amphiphilic molecule calculated?
How is the HLB value of an amphiphilic molecule calculated?
What does a lower HLB value indicate about a surfactant?
What does a lower HLB value indicate about a surfactant?
What type of properties do Tweens, polyoxyethylene derivatives of Spans, have?
What type of properties do Tweens, polyoxyethylene derivatives of Spans, have?
What should be the HLB value of an emulsifier to form stable emulsions with an oil phase?
What should be the HLB value of an emulsifier to form stable emulsions with an oil phase?
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What are the HLB value ranges for Spans, which are sorbitan esters?
What are the HLB value ranges for Spans, which are sorbitan esters?
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Study Notes
HLB Value and Calculation
- The HLB (Hydrophilic-Lipophilic Balance) value is a measure of the balance between hydrophilic and lipophilic parts of amphiphilic molecules.
- The HLB value is calculated by dividing the weight percentage of the hydrophilic part by five, according to Griffin.
- A lower HLB value indicates a lipophilic character, while a higher HLB value indicates a hydrophilic character.
- Griffin has established an empirical scale to determine the HLB values of surfactants, which enables the determination of the optimum range for each surface active substance effect.
Surfactants and HLB Values
- Spans, which are sorbitan esters, have lipophilic properties and low HLB values (1.8-8.6).
- Tweens, which are polyoxyethylene derivatives of spans, are hydrophilic and have high HLB values (9.6-16.7).
Emulsification and HLB Values
- To form stable emulsions, an emulsifier or emulsifier mixture with an HLB value equal to the HLB value of the oil phase should be used.
- Different formulas can be used to calculate the HLB values of surface active substances.
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Description
Test your knowledge of HLB value and calculation with this quiz. Learn about the balance between hydrophilic and lipophilic parts of amphiphilic molecules and understand how to calculate HLB values according to Griffin's empirical scale.