Early Tooth Development: Part 1
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Questions and Answers

What is the first branchial arch responsible for in embryonic development?

  • Production of enamel and dentin
  • Development of the maxilla and mandible (correct)
  • Development of the teeth and salivary glands
  • Formation of the oral cavity

    • Which sequence represents the correct sequential events of tooth development?

  • Bud, Cap, Induction, Initial crowning, Bell
  • Bell, Cap, Bud, Induction, Initial crowning
  • Initial crowning, Bud, Cap, Bell, Induction
  • Induction, Bud, Cap, Bell, Initial crowning (correct)

    • What are the principal cell types involved in guiding early tooth development?

  • Neurons and Astrocytes
  • Ameloblasts and Odontoblasts (correct)
  • Fibroblasts and Osteoblasts
  • Keratinocytes and Melanocytes

    • What migrates to the ventral side of the head early during embryogenesis?

    <p>NCCs from the neural tube</p> Signup and view all the answers

    During which week of intrauterine development does the invagination of the oral epithelium into mesenchyme occur?

    <p>Week 6</p> Signup and view all the answers

    What is the first stage in the development of teeth?

    <p>Bud stage</p> Signup and view all the answers

    What is the main role of the enamel knot during tooth development?

    <p>Crown development</p> Signup and view all the answers

    At which stage does the enamel organ take on a bell shape?

    <p>Early bell stage</p> Signup and view all the answers

    What is the main function of the stellate reticulum in the enamel organ?

    <p>Jelly-like ECM production</p> Signup and view all the answers

    What is the role of the dental papilla in tooth development?

    <p>Formation of dentine and pulp</p> Signup and view all the answers

    During which stage do we see a transition from cap to bell stage in tooth development?

    <p>Late cap stage</p> Signup and view all the answers

    What occurs during the late cap - early bell stage transition in tooth development?

    <p>Appearance of inner enamel epithelium and stellate reticulum</p> Signup and view all the answers

    What happens during the bud stage of tooth development?

    <p>Epithelium grows into ectomesenchyme</p> Signup and view all the answers

    When does the invagination of oral epithelium into mesenchyme occur?

    <p>Week 6 intrauterine</p> Signup and view all the answers

    What do we see at the late cap stage to early bell stage transition in tooth development?

    <p>Appearance of inner enamel epithelium and stellate reticulum</p> Signup and view all the answers

    What is the main function of the stellate reticulum in the enamel organ?

    <p>Jelly-like ECM production</p> Signup and view all the answers

    What is the composition of healthy dentine?

    <p>70% inorganic, 20% organic, 10% water</p> Signup and view all the answers

    What are the different types of dentine and where are they located within the mature tooth?

    <p>Primary dentine, secondary dentine, and tertiary dentine. Primary dentine is located in the crown, secondary dentine in the root, and tertiary dentine forms in response to injury or irritation.</p> Signup and view all the answers

    What cells are responsible for dentine formation?

    <p>Odontoblasts</p> Signup and view all the answers

    What is dentinogenesis?

    <p>The process of dentine formation</p> Signup and view all the answers

    At what stage of development does dentinogenesis start?

    <p>From 17-18 weeks intrauterine development</p> Signup and view all the answers

    What is the color of healthy dentine?

    <p>Yellow</p> Signup and view all the answers

    What is the role of odontoblasts in dentine formation?

    <p>Odontoblasts secrete a pre-dentine matrix and move inwards as dentine grows</p> Signup and view all the answers

    What is the physiological property of dentine that provides good support for enamel?

    <p>Elastic property</p> Signup and view all the answers

    What is the main inorganic component of dentine?

    <p>Hydroxyapatite (HAP)</p> Signup and view all the answers

    What is the main organic component of dentine?

    <p>Collagen</p> Signup and view all the answers

    What is the role of odontoblasts in dentine deposition?

    <p>Secreting extracellular matrix rich in collagen type I/III fibers and mineralizing the matrix</p> Signup and view all the answers

    What distinguishes the mantle dentine from the bulk of the dentine?

    <p>The thickness of collagen fibers and the fact that odontoblasts have not fully developed the ability to mineralize the matrix yet</p> Signup and view all the answers

    What is the main function of the circumpulpal dentine?

    <p>Forming the bulk of the tooth structure and entombing the odontoblast process within the mineralized matrix</p> Signup and view all the answers

    What happens as odontoblasts retreat pulpally during dentine deposition?

    <p>The odontoblast process is left 'entombed' within the mineralized matrix, forming tubules, and the cell process continues to elongate</p> Signup and view all the answers

    What are the characteristics of the extracellular matrix secreted by odontoblasts in dentine deposition?

    <p>Rich in collagen type I/III fibers and initially unmineralized</p> Signup and view all the answers

    What is the composition of the matrix from which mantle dentine is formed?

    <p>Matrix from new odontoblasts and existing dental papilla cells</p> Signup and view all the answers

    What occurs after the formation of mantle dentine during dentine deposition?

    <p>Odontoblasts secrete matrix and retreat pulpally</p> Signup and view all the answers

    What is the function of the collagen scaffold in dentine deposition?

    <p>Forming a network to accept the deposition of hydroxyapatite crystals and providing a structure for dentine formation</p> Signup and view all the answers

    What is the significance of odontoblasts having a high synthetic/secretory capacity in dentine deposition?

    <p>They are able to secrete the extracellular matrix crucial for dentine formation</p> Signup and view all the answers

    How is the bulk of the dentine different from the mantle dentine?

    <p>It is formed solely from odontoblasts and has thinner collagen fibers compared to mantle dentine</p> Signup and view all the answers

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