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Questions and Answers

A patient with severe hypothyroidism might present with which of the following conditions?

  • Hyperthyroidism
  • Myxedema (correct)
  • Euthyroid goiters
  • Thyroid cancer

Which of the following physiological responses would be expected with an increase in thyroid hormones?

  • Decreased cardiac output
  • Decreased heart rate
  • Decreased body temperature
  • Increased oxygen consumption (correct)

A patient taking levothyroxine begins to experience a rapid heart rate, weight loss, and insomnia. Which of the following adverse effects is the patient MOST likely experiencing?

  • Symptoms of hyperthyroidism (correct)
  • Hypersensitivity reaction
  • Adrenal insufficiency
  • Symptoms of hypothyroidism

Why is it generally recommended to avoid switching brands or types of levothyroxine?

<p>To ensure consistent therapeutic effects (A)</p> Signup and view all the answers

Which of the following conditions is a contraindication for thyroid hormone replacement therapy?

<p>Known hypersensitivity to the drug (C)</p> Signup and view all the answers

What is an important instruction to provide to a patient who has diabetes and is starting thyroid hormone replacement therapy?

<p>Monitor blood glucose levels closely and report hyperglycemia (B)</p> Signup and view all the answers

When should vital signs and weight be assessed in relation to a patient starting on thyroid replacement therapy?

<p>After diagnosis of hypothyroidism, both before and during therapy (B)</p> Signup and view all the answers

A patient on thyroid hormone replacement therapy reports weight loss, increased appetite and pulse rate, and decreased puffiness in their face and hands. What does this indicate?

<p>The patient is having a therapeutic response to the medication (A)</p> Signup and view all the answers

Which instruction should be emphasized when educating clients about taking thyroid hormones to promote an optimal response to therapy?

<p>Take the medication once a day in the morning, preferably before breakfast (C)</p> Signup and view all the answers

A client has been prescribed thyroid hormone replacement. What education should the nurse provide regarding adjustments to the medication?

<p>The client should not alter the dose or discontinue unless advised by their healthcare provider. (C)</p> Signup and view all the answers

Methimazole and propylthiouracil (PTU) are primarily used for the medical management of which endocrine disorder?

<p>Hyperthyroidism (B)</p> Signup and view all the answers

What is an important instruction to give to a patient undergoing treatment with radioactive iodine for hyperthyroidism?

<p>Maintain a distance of at least 6 feet from others (B)</p> Signup and view all the answers

After receiving radioactive iodine, what is an important action a patient should do to help with precautions?

<p>Increase fluid intake to 2-3L/day (D)</p> Signup and view all the answers

What allergy history should be carefully obtained before administering iodine procedures or medications?

<p>Allergy to iodine or seafood (D)</p> Signup and view all the answers

If a patient on methimazole develops a rash, what is the MOST important nursing action?

<p>Carefully document the rash and report it to the primary health care provider (D)</p> Signup and view all the answers

Why is thyroid hormone replacement therapy necessary when hypothyroidism develops?

<p>To compensate for the thyroid gland's inability to produce hormones (C)</p> Signup and view all the answers

Which of the following is a corticosteroid?

<p>Fludrocortisone (C)</p> Signup and view all the answers

A patient taking corticosteroids for an extended period is MOST at risk for developing which of the following conditions?

<p>Adrenocortical insufficiency (B)</p> Signup and view all the answers

Which of the following conditions is a common side effect associated with long-term corticosteroid use?

<p>Wasting of legs and arms (A)</p> Signup and view all the answers

What dietary modification is typically recommended for patients taking corticosteroids?

<p>Low sodium, high vitamin D, protein, and potassium (D)</p> Signup and view all the answers

What is a key monitoring parameter for a diabetic patient who is prescribed corticosteroids?

<p>Monitor blood glucose levels frequently (A)</p> Signup and view all the answers

Why should topical corticosteroids not be covered with occlusive dressings unless specifically directed by a healthcare provider?

<p>To prevent systemic absorption (D)</p> Signup and view all the answers

A patient's medication list includes Betamethasone, Cortisone, and Dexamethasone. What class of medications is the patient taking?

<p>Corticosteroids (A)</p> Signup and view all the answers

What are the three primary properties that describe the action of insulin?

<p>Onset, Peak, Duration (A)</p> Signup and view all the answers

A patient is experiencing tremors, tachycardia, and is diaphoretic. What condition should these signs and symptoms indicate to the nurse?

<p>Hypoglycemia (B)</p> Signup and view all the answers

A patient presents with hot, flushed skin along with fruity breath and polyuria. Thinking about DKA, what condition should these signs and symptoms indicate to the nurse?

<p>Hyperglycemia (D)</p> Signup and view all the answers

It is most important to assess what before the administration of insulin?

<p>Patient's past compliance with prescribed therapeutic regimen (C)</p> Signup and view all the answers

Under what circumstances can Regular insulin be administered intravenously?

<p>Regular insulin is the only insulin preparation that can be given IV (A)</p> Signup and view all the answers

Why should insulin glargine NEVER be mixed with other insulins?

<p>Mixing it causes glucose control to be lost and the insulin will not be effective. (B)</p> Signup and view all the answers

When planning the rotation of insulin injection sites, what consideration is MOST important?

<p>The pattern and spacing of injection sites (D)</p> Signup and view all the answers

What information about insulin administration should be documented on a patient's Medication Administration Record (MAR)?

<p>Injection site used (D)</p> Signup and view all the answers

What is the PRIMARY reason for rotating insulin injection sites?

<p>To prevent lipodystrophy (C)</p> Signup and view all the answers

If a patient is hypoglycemic, what would you NOT do?

<p>Administer IV fluids and dextrose immediately, regardless of gag reflex (A)</p> Signup and view all the answers

Which type of insulin has the fastest onset of action and is often used in insulin pumps?

<p>Rapid-acting insulin (D)</p> Signup and view all the answers

Why can intermediate acting insulin ONLY be administered subcutaneously?

<p>Cloudiness (C)</p> Signup and view all the answers

Which of the following instructions is important for a patient who has been prescribed Glucophage (metformin)?

<p>Hold 48 hours after iodine (B)</p> Signup and view all the answers

Which of the following side effects should a patient report for drugs ending in 'ide'?

<p>Hypoglycemia (C)</p> Signup and view all the answers

When should the medication Precose (acarbose) be taken in relation to meals?

<p>With the first bite of each meal (D)</p> Signup and view all the answers

What instruction regarding the timing of medication is important for a patient newly prescribed Prandin (repaglinide)?

<p>Take the medication 30 minutes prior to meals (C)</p> Signup and view all the answers

A patient with Parkinson's disease is experiencing increased hand tremor, dizziness, and difficulty in swallowing. How are these classified?

<p>Adverse reactions (C)</p> Signup and view all the answers

What is the mechanism of action of levodopa/carbidopa in treating Parkinson's disease?

<p>It helps to give the body more dopamine. (D)</p> Signup and view all the answers

What is one of the most common side effects of Symmetrel (amantadine)?

<p>Orthostatic hypotension (D)</p> Signup and view all the answers

What recommendation should be given to someone who has dry mouth in relation to medications for parkinsonism?

<p>Sips of water and icechips are recommended. (C)</p> Signup and view all the answers

Which of the following is a potential use for thyroid hormones?

<p>Treatment of euthyroid goiters (B)</p> Signup and view all the answers

What physiological change occurs with the increase in thyroid hormone levels?

<p>Increased oxygen consumption (D)</p> Signup and view all the answers

A patient with cardiac disease needs thyroid hormone replacement. What should the healthcare provider consider when initiating therapy?

<p>Patients with cardiac disease should be monitored more frequently. (D)</p> Signup and view all the answers

What indicates a therapeutic response to thyroid hormone replacement therapy?

<p>Increased appetite and mild diuresis (B)</p> Signup and view all the answers

After thyroid hormone therapy starts, a diabetic patient may require closer monitoring for:

<p>Signs of hyperglycemia, because thyroid hormones may reduce insulin effectiveness (C)</p> Signup and view all the answers

When a patient is prescribed methimazole for hyperthyroidism, what instructions should be provided?

<p>Report any signs of sore throat or headache immediately (D)</p> Signup and view all the answers

What is the correct procedure if a suspected iodine allergy is present before administering radioactive iodine?

<p>Document the allergy and contact the provider (D)</p> Signup and view all the answers

After receiving radioactive iodine, patients should maintain a distance of how many feet from others?

<p>6 feet (B)</p> Signup and view all the answers

Why is thyroid hormone replacement typically continued lifelong for individuals with hypothyroidism?

<p>It is necessary because hypothyroidism results from irreversible damage to the thyroid gland (B)</p> Signup and view all the answers

What therapeutic use is commonly associated with corticosteroids?

<p>Decreasing allergic reactions (A)</p> Signup and view all the answers

What condition is a long-term risk with corticosteroid use?

<p>Osteoporosis (B)</p> Signup and view all the answers

Why is it important not to discontinue corticosteroids abruptly?

<p>To allow the adrenal glands to resume normal function (B)</p> Signup and view all the answers

A patient is prescribed corticosteroids. What dietary advice is most appropriate?

<p>Restrict sodium and increase vitamin D and protein intake (C)</p> Signup and view all the answers

What should a patient taking corticosteroids for more than five days do while discontinuing their therapy?

<p>Taper the dose of the medication (A)</p> Signup and view all the answers

What should the nurse tell a patient about applying topical corticosteroids?

<p>Avoid sunlight unless told otherwise. (B)</p> Signup and view all the answers

A patient is ordered to receive Florinef for medication. Which condition does this medication treat?

<p>Adrenocortical deficiency (B)</p> Signup and view all the answers

What aspect of diabetes does assessing HgBA1C as part of a pre-administration assessment for insulin relate to?

<p>The patient's past compliant with the plan of care (B)</p> Signup and view all the answers

Why is insulin glargine typically administered at bedtime?

<p>To provide a basal level of insulin throughout the night and day (A)</p> Signup and view all the answers

Why is it important to plan the injection site when administering insulin?

<p>To ensure consistent insulin absorption (D)</p> Signup and view all the answers

Why is it not safe to administer oral medications to those going through a hypoglycemic reaction?

<p>The gag reflex is suppressed and the patient may aspirate liquids or solids (A)</p> Signup and view all the answers

Which intervention is needed when a patient is ordered to receive Humalog Mix 75/25 insulin suspension?

<p>Check that the solution of the insulin is cloudy. (C)</p> Signup and view all the answers

What patient education should be included with a prescription for Glucophage (metformin)?

<p>Take with meals to reduce abdominal discomfort. (D)</p> Signup and view all the answers

Drugs that end in 'ide' such as Glimepiride, Glyburide, and Glipizide are important to educate patients report which side effect?

<p>Hypoglycemia (C)</p> Signup and view all the answers

Precose (acarbose) lowers blood sugar, but how?

<p>Will not cause hypoglycemia if used alone. (D)</p> Signup and view all the answers

Increased dosing of Prandin may influence what?

<p>If skips a meal, skip a dose (D)</p> Signup and view all the answers

What causes Parkinson's disease?

<p>Excess of Acetylcholine (D)</p> Signup and view all the answers

While working with the patient that has parkinsonism, you hear the doctor has ordered Tolcapone (Tasmar). This medication can be toxic to what?

<p>Liver (B)</p> Signup and view all the answers

The patient states they have been experiencing dry mouth from their parkinsonism medications. What is the nurse's best response?

<p>Try ice chips, frequent mouth care, and sips of water for this. (A)</p> Signup and view all the answers

You are taking care of a Parkinson's disease patient in which the provider has prescribed selegiline. What would you educate to your patient in relation to food?

<p>Avoid foods containing tyramine. (D)</p> Signup and view all the answers

A patient with parkinsonism that has a tremor, what medication would be ordered?

<p>An Anticholinergic (D)</p> Signup and view all the answers

What intervention is most important when providing medications to a patient with memory loss and reduced cognition?

<p>Observe for adverse reactions. (B)</p> Signup and view all the answers

A patient with Alzheimer's disease has an adverse reactions to their medications that includes anorexia, n/v, and dizziness. What can you educated the patient in relation to this?

<p>These can go away, but reach out to your provider to be seen. (B)</p> Signup and view all the answers

Myasthenia gravis reduces the production of what naturally in the body?

<p>Acetylcholine (A)</p> Signup and view all the answers

You remember from clinicals that cholinergic medications can be used for which conditions?

<p>Urinary retention, glaucoma, and myasthenia gravis (B)</p> Signup and view all the answers

A patient with a cholinergic order is reporting salivation and muscle weakness, what would be your next step and what condition are you worried about?

<p>Cholinergic Crisis, administer Atropine (D)</p> Signup and view all the answers

A patient has an adverse affect and are experiencing a urinary retention from their medication. What could the provider order?

<p>Urecholine (C)</p> Signup and view all the answers

A patient takes Benadryl for allergies and Urecholine, a cholinergic for urinary retention. Can these be taken together?

<p>No, anticholinergics will cancel out the effects of the urecholine (B)</p> Signup and view all the answers

What is an expected side-effect if a cholinergic gets into your eyes?

<p>Pupils will become small (B)</p> Signup and view all the answers

What class of medications are you most concerned with while assessing for an allergy to Sulfa?

<p>Diuretics (C)</p> Signup and view all the answers

What would you educate your diabetic patient about to expect regarding their illness, if they are also taking a diuretic?

<p>If you have blood glucose concerns contact health staff. (B)</p> Signup and view all the answers

A nurse has an order for a patient that needs to take a few diuretics. They need to give it but notes that the BUN and Creatinine are 3x the normal value. What should they do?

<p>Hold medication per report and consult MD. (A)</p> Signup and view all the answers

A patient being treated for hypothyroidism with levothyroxine reports persistent constipation and increased fatigue. Which action is the MOST appropriate?

<p>Assess the patient's medication list for other drugs known to cause constipation. (B)</p> Signup and view all the answers

A patient is prescribed methimazole for hyperthyroidism. What potential side effect should the patient be taught to immediately report to their healthcare provider?

<p>Sore throat and fever (A)</p> Signup and view all the answers

A patient with iodine allergy is being prepared for a thyroid scan using radioactive iodine. Which intervention is MOST important?

<p>Pre-medicate with an antihistamine and corticosteroid. (B)</p> Signup and view all the answers

A patient on long-term corticosteroid therapy is scheduled for surgery. What adjustment to their medication regimen is MOST likely needed?

<p>Increase the corticosteroid dose to help the body manage surgical stress. (A)</p> Signup and view all the answers

A patient prescribed prednisone reports insomnia. What instruction should the nurse provide?

<p>Adjust the timing of the prednisone dosage to earlier in the day. (B)</p> Signup and view all the answers

A patient with diabetes who is prescribed corticosteroids should receive which of the following instructions regarding blood glucose monitoring?

<p>Increase the frequency of blood glucose monitoring, especially after meals (D)</p> Signup and view all the answers

A patient is prescribed fludrocortisone for adrenocortical insufficiency. Which of the following should the nurse monitor to determine the effectiveness of the medication?

<p>Blood pressure and electrolyte balance (A)</p> Signup and view all the answers

A patient taking insulin reports consistently high blood sugar levels in the morning. Which action is MOST appropriate?

<p>Suggest the patient consult with their healthcare provider for evaluation and possible adjustment of the insulin regimen (B)</p> Signup and view all the answers

A patient is prescribed insulin glargine. What information should the nurse offer to the patient to help the patient understand the nature of this medication?

<p>Insulin glargine is a long-acting insulin that provides a basal level of insulin. (B)</p> Signup and view all the answers

A patient who takes insulin reports that they are planning to start a new exercise program. Which adjustment to their insulin regimen should be anticipated?

<p>Insulin dosages may need to be decreased, especially before exercise. (A)</p> Signup and view all the answers

A patient receiving Glucophage (metformin) is scheduled for a CT scan with contrast dye. Which action is MOST appropriate?

<p>Hold the Glucophage 48 hours after the procedure. (D)</p> Signup and view all the answers

A patient taking medications from the sulfonylurea class of antidiabetic medications - Glimepiride, Glyburide, and Glipizide - reports feeling shaky, sweaty, and confused. What should be the next nursing action?

<p>Check the patient's blood glucose level (A)</p> Signup and view all the answers

Which of the following actions is an important action a nurse should take when administering Acarbose?

<p>Administer medication with the first bite of foods (A)</p> Signup and view all the answers

What education should be offered to a patient that is taking Prandin (repaglinide)?

<p>If you skip a meal, skip a dose (C)</p> Signup and view all the answers

What is understood about the disease process of Parkinson's?

<p>Parkinson's disease is caused by a deficiency of dopamine and an excess of acetylcholine in the CNS (D)</p> Signup and view all the answers

The doctor orders Tolcapone (Tasmar). The nurse understands that this medication can be toxic to which organ?

<p>Liver (C)</p> Signup and view all the answers

The patient is prescribed selegiline. What food interaction education is most important for the nurse to offer the patient?

<p>Tyramine food interactions (C)</p> Signup and view all the answers

A patient demonstrates an understanding of carbidopa/levodopa when they state:

<p>&quot;This medication will turn my urine and sweat a dark color.&quot; (C)</p> Signup and view all the answers

The patient has been prescribed a medication for Alzheimer's disease. The patient has been having anorexia, nausea/ vomiting, and dizziness. What would be the most correct response?

<p>&quot;Those side effects are usually mild and will go away.&quot; (B)</p> Signup and view all the answers

How do cholinergic medications assist with patients with glaucoma?

<p>it helps with increased pressure within the eye by cause by obstruction of outflow of aqueous humor (D)</p> Signup and view all the answers

What parameter is MOST important to monitor when administering selegiline to a patient with parkinsonism?

<p>Blood pressure (C)</p> Signup and view all the answers

Which of the following best describes the effect of cholinergic drugs on bladder function?

<p>They promote bladder muscle contraction and facilitate urination (C)</p> Signup and view all the answers

A patient with a known history of glaucoma is prescribed a cholinergic medication. What anticipated therapeutic effect should the nurse expect regarding intraocular pressure?

<p>Reduced intraocular pressure (A)</p> Signup and view all the answers

A patient is prescribed a cholinergic medication. Which assessment finding would warrant immediate intervention due to the risk of cholinergic crisis?

<p>Patient exhibits muscle weakness and increased salivation (B)</p> Signup and view all the answers

A patient is taking a cholinergic medication for urinary retention and is now prescribed an antihistamine for seasonal allergies. What could be the MOST significant concern?

<p>Reduced effectiveness of the cholinergic medication (D)</p> Signup and view all the answers

A patient is prescribed a cholinergic eye drop medication. What potential side-effect should the nurse include in the patient education?

<p>Pupil constriction (C)</p> Signup and view all the answers

The nurse correlates which data as a contraindication in the administration of Urecholine for urinary retention?

<p>Peptic ulcer disease (A)</p> Signup and view all the answers

Which concurrent medication would be concerning with a cholinergic due to toxicity?

<p>Aminoglycoside antibiotics (B)</p> Signup and view all the answers

What is the priority intervention when a patient displays signs of cholinergic crisis?

<p>Administer atropine intravenously (C)</p> Signup and view all the answers

When educating a patient about benztropine, a cholinergic-blocking agent prescribed for parkinsonism, what would be a priority?

<p>Using ice chips or sugar free fluids to alleviate dry mouth (B)</p> Signup and view all the answers

What intervention is MOST appropriate for the nurse to recommend to a patient experiencing constipation as an adverse effect of cholinergic-blocking medications?

<p>Increasing fluid intake (B)</p> Signup and view all the answers

Which statement made by the patient demonstrates an understanding of the effects of benztropine (Cogentin)?

<p>&quot;I should expect to have less saliva in my mouth while I'm taking this medication&quot; (D)</p> Signup and view all the answers

Parkinson's Disease affects levels of what in the brain?

<p>Deficiency of dopamine and excess acetylcholine (D)</p> Signup and view all the answers

A diagnosis of Parkinson's Disease is made. What statement would offer insight as to the disease affecting them?

<p>&quot;There is no cure, but drugs are used to help treat symptoms&quot; (B)</p> Signup and view all the answers

Due to the adverse side effects due to levadopa/ carbidopa, what assessment findings would you look for?

<p>N/V, mental changes, and increased movements (D)</p> Signup and view all the answers

Carbidopa is ordered for your patient. Knowing the affects of it, you know:

<p>It has no effect when given alone (C)</p> Signup and view all the answers

What symptoms require consultation?

<p>Confusion, leukepenia, and neutropenia (D)</p> Signup and view all the answers

You have a patient that reports dry mouth. What can the nurse do to help?

<p>Offer sips of water or ice ships (B)</p> Signup and view all the answers

What are some considerations to tell your clients when working with Lamatrogine while they are taking it for parkinsonism?

<p>Potentially fatal rashes can occur (D)</p> Signup and view all the answers

What is not safe to administer?

<p>Give oral medications (C)</p> Signup and view all the answers

What is a priority nursing intervention when administering Humalog Mix 75/25?

<p>Cloudy and needs mixing (D)</p> Signup and view all the answers

What needs to be included with each dose?

<p>All of the above (D)</p> Signup and view all the answers

What education is required when giving Glucophage (metformin)?

<p>Give with meals (A)</p> Signup and view all the answers

What is important report with Sulfonylureas?

<p>Hypoglycemia (D)</p> Signup and view all the answers

What is the method of action with Precose (acarbose)?

<p>Will not cause hypoglycemia (C)</p> Signup and view all the answers

What should happen if the patient skips a meal while ordering prandin?

<p>Skip a dose (D)</p> Signup and view all the answers

Patient teaching for long term corticosteroid therapy should include

<p>Avoid all vaccinations (A)</p> Signup and view all the answers

If a diabetic patient has been prescribed corticosteroids it is important to tell them:

<p>Sugar may incrrease (A)</p> Signup and view all the answers

When on corticosteroid therapy, it is important NOT to d/c abruptly because

<p>Adrenal insuffiency can occur (D)</p> Signup and view all the answers

What diet is best for corticosteroid therapy?

<p>low in sodium, high in vitamin D, protein and potassium (B)</p> Signup and view all the answers

Name a way to monitor and manage care when someone has increased fluid volume?

<p>Excess fluid volume: Check for visible edema, keep accurate fluid intake and output record, obtain daily weight (D)</p> Signup and view all the answers

A goal of synthroid is?

<p>Increase thyroid hormone levels (C)</p> Signup and view all the answers

Known hypersensitivity is to which disorder that correlates synthroid medications?

<p>Hyperthyroidism (A)</p> Signup and view all the answers

Taking synthroid can have an adverse affect of?

<p>Hyperthyroidism (D)</p> Signup and view all the answers

What action would you take if you recognize upper respiratory reactions?

<p>Monitor for signs of infection, particularly upper respiratory infection in visitors and other health care personnel (C)</p> Signup and view all the answers

What distance should the radioactive iodine patient maintain in relation to others

<p>6 feet (D)</p> Signup and view all the answers

Which finding would determine that the treatment is at a therapeutic range?

<p>Weight loss, mild diuresis, increased appetite, increase pulse, decreased puffiness of face, hands, and feet (A)</p> Signup and view all the answers

Which finding would be concerning when receiving Methimazole while pregnant or not?

<p>Sore throat and headache (D)</p> Signup and view all the answers

What action is needed with methimazole in relation to a rash?

<p>Carefully document affected areas, noting size, texture, extent of rash, and report occurrence of rash to the primary health care provider if the patient (C)</p> Signup and view all the answers

Why is it important to take allergy hx with a thyroid scan?

<p>Because of iodine use, particularly to iodine procedure (B)</p> Signup and view all the answers

Why is Thyroid medication needed for the rest of their lives?

<p>The thyroid will always underproduce the T3 and T4 (B)</p> Signup and view all the answers

When is the best time to weight and take vital signs for someone that has hypothyroidism

<p>After diagnosis and before therapy (A)</p> Signup and view all the answers

A patients diabetes becomes what in terms of blood glucose while receiving thyroid replacement therapy?

<p>Closely monitor for sign of hyperglycemia, notify it problem occurs (D)</p> Signup and view all the answers

Flashcards

Uses of Levothyroxine

Treats hypothyroidism, myxedema, cretinism, and euthyroid goiters; may prevent thyroid cancer

Thyroid hormone effects

Metabolic rate, heart/respiratory rate, body temperature, cardiac output, and oxygen consumption.

Adverse reactions to Levothyroxine

Signs of overdose and hyperthyroidism during titration.

Levothyroxine contraindications

Known hypersensitivity, uncorrected adrenal cortical insufficiency (Addison's), and thyrotoxicosis.

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Levothyroxine precautions

Cardiac, renal diseases, hypertension, and diabetes need caution.

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Monitor for with anti-thyroid meds

Vital signs and weight monitoring before & during, look for hyperthyroidism signs.

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Instructions for taking thyroid medication

Once a day, initial low dose, early in the morning, preferably before breakfast.

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Important medication rule to note

Never change brands or types. Don't alter dose or discontinue without advice.

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Propylthiouracil/Methimazole uses

Medical management of hyperthyroidism. Can also prepare for thyroid surgery.

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Adverse reactions of antithyroid meds

Sore throat, headache, nausea, vomiting, paresthesias.

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Serious adverse reactions of anti-thyroid meds

Agranulocytosis (decreased WBC), thrombocytopenia. Monitor for infection.

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Allergies as a precaution for thyroid meds

Closely watch for allergy to iodine or seafood.

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Coritcosteroids

Known as glucocorticoids. Used for anti-inflammation.

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Corticosteroids treat?

Adrenocortical insufficiency (replacement therapy - Florinef), allergic, connective diseases.

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Corticosteroids treat?

Adrenocortical insufficiency (replacement therapy - Florinef), allergic, connective diseases.

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Corticosteroids function?

Anti-inflammatory, regulates blood pressure, carbs/fat metabolism, immunosuppression during stress

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Cushy Carl lab changes

Increased sodium, decreased potassium, high glusose, decreased calcium

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Important lab reminders for meds

Never omit dose (parenterally if can't take PO), watch electrolytes, EKG, TB skin test results

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Corticosteroid Instructions

Monitor glucose, taper dose if long-term, take with food, no live vaccinations.

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Corticosteroid S/S to report

Report signs of infection, epigastric burning, fluid volume excess.

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Corticosteroid drugs

Betamethasone, Cortisone, Dexamethasone, Prednisone, and Methylprednisolone

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Insulin's Onset

How quickly the insulin starts to lower blood sugar.

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Insulin's Peak

When the blood sugars are at their lowest point - right after injection.

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Insulin's Duration

How long insulin lowers that persons blood sugar.

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Low blood sugar symptoms

Tremors, irritability, restlessness, excessive hunger, diaphoresis, and/or depression

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High blood sugar reminders

Hot flushed skin, fruity breath, polyuria, loss of appetite, tiredness, and/or thirst

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Rules regarding regular insulin

Regular insulin should be given 15-30 minutes before meals for best results.

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Other insulin instructions

Insulin glargine, don't dilute with any solution, they lose potency, check with 2 nurses

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Injection site rules

Prevents lipodystrophy, abdomen is biggest for absorb, record site

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Administration rules with hypo's

Don't give oral fluids/substances to counter hypoglycemia unless swallowing and gag reflex are present.

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Insulin Humalog/Novalog characteristics

Rapid, Clear, can use SC or Iv. Is the only insulin that can be used for IV. Can anticipate hypoglycemia mid morning

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Intermediate insulins characteristics

Cloudy, anticipate hypoglycemia around supper, peak over 6-14 hours.

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Long lasting insulin characteristics

Clear, peakless, HS snack.

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Anti-convulsants treat

Treats patients with seizures, and bipolar disorder

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Side effects of Anti-convulsants

Drowsiness, headache, slur speech, gingival hypersplasia

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Important instruction considerations for drug

If rash, may need to de drug. Be careful and watch when drug effectiveness starts.

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Anti-convulsant contraindications

Sore throat, bleeding signs, bright lights, convulsion people

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Nursing considerations

Frequent vs, keep equip nearby. Depression, Confusion common, do not use if res illness

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Health teaching considerations

Drowsiness, sedation, common. Also gingival hyperplasia, good health needed.

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Phenytoin can cause

Liver problems, kidney problems . levels between 10/20 are optimal, if over, will damage bodies functions.

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What the adverse reactions

Difficulty Swallowing, tremors, ha, dizziness, increased had tremor.

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When Disease progresses

No longer working properly

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Dopamine Symmetrel

Indicated to treat post disease

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What does it treat

For dysuria, urinary retension, and for constipation

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Blood flow

Reduced blood flow

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Actolyne

Def from too much actolyne

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Blood helps

Uses: adjuncts to blood

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Hypertension Crisis

From foods

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Slow heart

Slow Conjunction/ decrease heart rate

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Euthyroid goiters

An enlargement of the normal thyroid gland. Caused by hypothyroidism.

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Levothyroxine

The drug of choice for hypothyroidism, it should never be changed between brands or types.

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Hypothyroidism therapeutic response

Weight loss, mild diuresis, increased appetite/pulse, and decreased puffiness.

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Thyroid hormone administration

These medications are administered once daily, starting with a low dose.

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Sodium Iodide

Used to treat hyperthyroidism, need to be given orally with methimazole or propylthiouracil to prepare for thyroid surgery.

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Documenting skin/rash affected areas

Carefully document areas and contact doctor, it could be methimazole (Tapazole) or propylthiouracil (PTU)

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Slowing the breakdown

This occurs by slowing the breakdown of incretins, so insulin is released over a longer period of time.

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Closely monitor blood sugar

May occur if the patient is a diabetic.

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Precautions for taking sodium?

If the patient has an existing electrolyte imbalance, they can't take this medication.

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Administration of metformin

Take after meals to reduce GI upset.

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What do you have to monitor?

BUN, creatinine, liver function tests, blood and urine glucose, and HgbA1C.

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Metformin considerations

This should not be given with iodine-containing contrast medication, hold for 48 hours

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Starlix considerations

Newest drug class, may reduce CV risk

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Anti-seizure meds during pregnancy

An association between anticonvulsant use in pregnant women and birth defects

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D/C for seizures

This should never be stopped abruptly.

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Drug changes?

Check and report if it changes. (aplastic anemia, leukopenia, and thrombocytopenia).

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Parkinson's is thought to be with?

Is thought to be from deficiency of dopamine and excess of acetylcholine with the CNS.

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Symmetrel (amantadine)

Is indicated the treatment of Parkinson's disease (Paralysis Agitans), postencephalitic parkinsonism, and symptomatic parkinsonism

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Therapy used?

Is used a used as adjunctive therapy in all forms of parkinsonism and in control of drug induced extrapyramidal disorders

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Atropine helps and helps decreases what

Decrease/ brady with coly cholc

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What dosage may need to be decreases and why?

May be needed in some individuals. Apnea

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Take meds in what?

To avoid GI upset

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Used with what

To make treatment.

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What inhibitor used what?

Is a MAO-B inhibitor

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Actlycone is important to do what

For memory and thinking.

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Meds acts like

They act like neurotransmitter acetylcholine or inhibit release of enzyme acetylcholinesterase

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Anti Myg gra

Disease that involves rapid fatigue of skeletal muscles because of lack of acetylcholine released at nerve endings of parasympathetic nerves

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Cholenergic crisis signs and symptoms

Increase a

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Why use drug for Urinary ?

For urinary r

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What does Atropine help to do.

To reduce secretion, vagal induce Brady Colicc

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What this drug help if they have what?

It Is for nitrates

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What does Betta Blocker help.

The beta

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What action is

The action is to reduce the pain

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The adverse from reduce to what?

The cause from reduce in

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What does inhhibit.

Inhibib what?

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What dose HTN

Used in a first-line

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The action black the what

Block alpha

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What is cardiac activity

Increases cardiac but also creates activity.

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hold if dig

This will help if you hold these with a potassium , dig and with what.

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The Ac is that do or does?

Binding bile

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Study Notes

Thyroid Hormones

  • Used to treat hypothyroidism, myxedema (severe hypothyroidism in adults), and cretinism (congenital hypothyroidism)
  • Also used for euthyroid goiters (enlargement of normal thyroid gland) and thyroid cancer
  • Cause an increase in metabolic rate of tissues, heart and respiratory rate, body temperature, and cardiac output
  • Increase oxygen consumption, metabolism of fats/proteins/carbohydrates, and mental activity
  • The drug of choice is Levothyroxine (Synthroid), and brands/types should not be changed
  • Most common adverse reactions are signs of overdose and hyperthyroidism, along with titration of drug
    • Overdose symptoms are V/D, diarrhea, wt loss, tachycardia, palpitations, angina, nervousness, tremors, irritability, insomnia, menstrual irregularities, sweating, and heat intolerance
  • Adverse reactions other that hypothyroidism symptoms are rare
  • Contraindicated in patients with hypersensitivity to drug, uncorrected adrenal cortical insufficiency (Addison’s), and thyrotoxicosis (thyroid storm)
  • Should be used cautiously in patients with cardiac/renal disease, hypertension, or diabetes
  • A diagnosis of hypothyroidism should be obtained and therapy started after initial vital signs and weight are taken
  • Monitor vital signs and weight, with signs of hyperthyroidism signalling excessive drug dosage
  • Some results can be seen in 3-4 days, with full effects taking several weeks (6-8 wks)
  • Therapeutic responses include weight loss, mild diuresis, increased appetite/pulse, and decreased puffiness of face/hands/feet
  • Administer thyroid hormones once a day, initially at low dose (may increase over weeks), early in the morning preferably before breakfast (30-60 min)
  • Closely monitor clients with diabetes on thyroid hormone replacement therapy, taking into account signs of hyperglycemia and notifying if a problem occurs
  • Weigh weekly and report significant weight gain or loss, and consult provider before altering or discontinuing the dose
  • Replacement therapy is for life, with periodic thyroid function tests needed (T4 & TSH) (q 6-8 wks)
  • Replacement therapy is necessary if hypothyroidism develops, and follow up evaluations are necessary to review the thyroid gland and treatment effectiveness
    • Levothyroxine sodium, sold as Levothroid and Synthroid, are thyroid replacements
  • Methimazole (Tapizole) and propylthiouracil (PTU) are used for the medical management of hyperthyroidism
  • Sodium iodide (131I) may be administered orally with methimazole/propylthiouracil to prepare for thyroid surgery
  • Radioactive iodine treats hyperthyroidism and selected cases of cancer of thyroid - This radioactive isotope accumulates in thyroid gland cells, which causes destruction of the cells without damaging cells throughout the body
  • Generalized system reactions to antithyroid drugs include sore throat (headache) and nausea (vomiting, paresthesias)
    • Severe system reactions include agranulocytosis (decreased WBC) and thrombocytopenia
  • A careful allergy history should be performed, particularly for iodine/seafood given prescription of an iodine procedure
  • Document affected areas and note size, texture, extent of rash, and report it to primary healthcare provider if rash is experienced while taking methimazole (Tapazole) or propylthiouracil (PTU)
  • For radioactive iodine, follow department of nuclear medicine directions regarding precautions - Maintain 6 feet distance from others - Do not share utensils or cook for others - Limit contact with others (30 min/day/person) - Increase fluid intake (2-3L/day)

Corticosteroids

  • Properties include anti-inflammatory, regulation of blood pressure (increases), metabolism or carbohydrates/protein/fat, and immunosuppressant
  • Also provide protection (released) during stress, as well as CNS responses that increase mood
  • Treats adrenocortical insufficiency, allergic reactions, collagen diseases (lupus), dermatologic conditions, and rheumatic disorders
  • Also treats shock (bp increases), such as with Florinef
  • Side effects include Buffalo hump, moon face, oily skin/acne, osteoporosis, and excess fat deposits on trunk
  • Other side effects include wasting of legs/arms, altered skin pigmentation, weight gain, and increased Na+ levels (decreasing K+), increased glucose, and decreased Ca+
  • Medications should never be omitted, and if unable to take orally, get order for parentally
  • Should watch electrolytes, examine EKG & TB skin test results
  • For diabetics, monitor blood glucose levels and take with food or milk early in morning
    • Never discontinue if given > 5 days
    • Can result in adrenal insufficiency if discontinued without tapering
    • Make sure to eat a diet low in sodium, high in vitamin D, protein, and potassium
  • Should monitor pt. for risk of infections and acute pain, as well as reporting any signs/symptoms of each
  • Monitor for excess fluid volume, as well as fluid intake & output records and daily weights
  • If topical, do not cover and avoid sunlight on the treated area
  • Many of the drugs end in “one”
  • Medications include Betamethasone (Celestone), Cortisone, Dexamethasone (Decadron), Hydrocortisone (Solu-cortef), Methylprednisolone (Medrol), Prednisolone (Prelone), and Fludrocortisone (Florinef)

Antidiabetic Drugs

  • Properties of insulin include: onset (when it starts), peak (max strength), duration (how long it lasts)
  • If hypoglycemia occurs, a patient will experience tremors/tachycardia, irritability, restlessness, excessive hunger, and diaphoresis/depression
  • Hypoglycemia is referred as "TIRED", as well as "Cool and clammy", a candy
  • Signs of hyperglycemia, such as hot/flushed skin, fruity breath, polyuria, loss of appetite, tiredness, and thirst
  • Hyperglycemia is referred as "Hot and Dry", with "Sugar to HIGH!”
  • A patient’s compliance with prescribed therapeutic regimen should be evaluated via health care provider with HgbA1C (2.5-6.0 % = good, > 10% = bad)
  • Regular insulin is only preparation given via IV
  • Regular insulin should be given 15-30 minutes before meals for optimal results
  • Novolog is given immediately (5-15 minutes) before meal, while Humalogg is given 15 minutes before meal or immediately after meal
    • Do not mix or dilute insulin glargine with any other insulin or solution - this will lose glucose control and render the drug ineffective
  • Administer insulin glargine SC once daily at bedtime (HS)
  • Check insulin dose with two nurses
    • Be sure to know how to mix insulins
  • Rotation site should be carefully planned, with 1-1 ½ inches apart and a write in the patient’s chart
  • The abdomen is the fastest absorption rate, then upper arm, then thigh
  • Be sure to record the site on the MAR
  • Avoid lipodystrophy (atrophy of SQ fat) through rotation, which interferes with absorption by slightly dimpling or pitting SQ fat
  • Never give oral fluids/substances unless swallowing and gag reflexes are present, and monitor/report signs of hypoglycemic reaction
  • Rapid Acting includes Humalog and Novalog), given clear and can be given IV/SC to anticipate hypoglycemia mid morning and have peaks of 1-3 hours for durations of 3-5 hours
  • Short Acting (Regular) such as Humulin R or Novolin R are given clear and can be given IV/SC, primarily to check for hypoglycemia before lunch

Antihypoglycemic Agents (Oral)

  • Glucagon, which is administered, Subcut, IM, and IV is used for hypoglycemia in the diabetic client and is more effective once glycogen stores are present
  • Common side effects include nausea and vomiting, while patients on Warfrin may potentiate anticoagulant effects of coumadin if used for extended amounts of time
  • Administration techniques involves following up with oral glucose once the client is awake and able to swallow
  • Glucophage (metformin) should be administered with meals to counter the risks of NV, anorexia, hypoglycemia (rare), diarrhea, and flatulence from the Biguinides
  • Monitor BUN, creatinine, and liver function, as well as reporting hypoglycemia, hepatotoxicity, and blood dyscrasias
  • Some Sulfonylureas are Diabinese (chlorpropamide), Amaryl – Glimepiride (elderly), DiaBeta (Glyburide ), and Glucotrol (Glipizide elderly)
  • Meglitinides such as Prandin and Starlix are drugs given ~30min before a meal
  • Precose (acarbose) is administered with the first bite each meal (3 x day), mainly in Type II if unresponsive for diet/exercise or adjunct therapy with metformin/sulfonylureas
  • Side effects for Precose includes if hypoglycemia in conjunction with other agents or hepatotoxicity, a well as reporting if seen.
  • Thiazolidinediones for diabetes can alter oral contraceptives needs to be observed so that an adequate dose is given
  • These drugs needs to be taken with meals and always ingested after administering
    • Medications include Actos and Avandia
  • The three DPP-4 pill inhibitors (Januvia, Onglyza, Tradjenta) are for type 2 diabetes
    • taken once a day
    • do not promote weight gain
    • often combined with metformin
    • have very little side effects
  • Be aware which of the side effect to report to the provider

GLP-1 Receptor Agonists

  • Exenatide is injected once per week with action matching Byetta given above
  • Liraglutide (Victoza) is injected at the same time each day
  • Dulaglutide and semaglutide are injected each week and given if stimulated to release insulin

Anticonvulsants

  • Treats seizures of all types
  • Treats neuropathic pain, such as with Pregabalin (Lyrica)
  • Treats bipolar disorders such as with Carbamazepine (Tegretol)
  • Treats anxiety disorders and mania such as with Valproic Acid, (Depakote)
  • Treats status epilepticus with Diazepam (Valium)
  • An association between anticonvulsant use in pregnant women and birth defects has been found
  • Adverse Reactions include CNS (drowsiness, headache/somnolence, nystagmus, ataxia, and slurred speech) and GI (NV/D, anorexia, constipation, and gingival hyperplasia)
  • Adverse reactions also include cardiovascular dysrthmias and others, such as skin rashes, stevens johnson syndrome, urinary frequency, and hematologic changes (pancytopenia, leukopenia, aplastic anemiia, and thrombocytopenia)
  • Barbiturates
    • Phenobarbital
    • Phenobarbital sodium - Luminal Sodium
  • Benzodiazepines
    • Clonazapam - Klonopin
    • Clorazepate - Tranxene
    • Diazepam - Valium
    • Lorazepam - Ativan
  • Hydantoins
    • Phenytoin sodium - Dilantin
  • Succinimides
    • Ethosuximide - Zarontin
  • Sodium Channel Inactivator Drugs:
    • Lacosamide-Vimpat (Schedule V subs.)
  • Miscellaneous Preparations
    • Carbamazepine - Tegretol
    • Gabapentin - Neurontin
    • Magnesium sulfate
    • Pregabalin - Lyrica
    • Topiramate - Topamax
    • Valproic acid - Depakote, Depekene
    • Lamotrigine - Lamictal
    • Levetiracetam- Keppra
  • Pregabalin (Lyrica) is also used for neuropathic pain, and postherpetic neuralgia
  • Lorazepam (Ativan) is also a preanesthetic
  • Carbamazepine (Tegretol) is also for bipolar disorder and neuralgia
  • Gabapentin (Neurontin) also treats neuralgia
  • Watch for electrolyte activity if you have taken TB skin test results
  • Mag sulfate is for seizures associated with eclampsia and acute nephritis in children
  • Topiramate (Topamax) and valproic acid (Depakote) help with migraine headaches
  • Valproic acid (Depakote) also helps with mania
  • Medications may require frequent adjustments in the beginning of therapy, and Plasma levels are checked to monitor for therapeutic level and toxicity The drug must never be stopped abruptly, since this may result in return of seizures or status epilepticus
  • Drowsiness is common when administering drugs, where it's encouraged to rise slowly from bed
  • Severe and potentially fatal rash can occur in clients taking lamotrigine (Lamactil) • Check blood levels regularly. • Don’t put anything in the mouth of a convulsing person. • Avoid alcohol

Antiparkinsonism

  • Parkinson's disease
  • Parkinson-like symptoms (extrapyramidal) as a result of injury, drug therapy, or encephalitis
  • Restless leg syndrome
  • Viral infections (amantadine)
  • Adverse Reactions: as the disease progresses, the response to the drug may become less and the period of time that each dose is effective begins to decrease, leading to more frequent doses, and more adverse reactions
  • Choreiform movements, dystonic movements, mental changes, anorexia, n/v, abdominal pain, constipation, dry mouth, difficulty in swallowing, increased hand tremor, ha, and dizziness can occur, so use caution
  • Carbidopa has no effect when given alone
  • Symmetrel (amantadine) is indicated in the treatment of parkinsonism
  • The drug is also used for Parkinson’s disease (Paralysis Agitans), postencephalitic parkinsonism, and symptomatic parkinsonism with Amantadine s/e to including: orthostatic, hypotension, depression, CHF, psychosis, urinary retention, convulsion, leukopenia, and neutropenia confusion, and anorexia.
  • Use is used an adjunctive therapy to tx. all from of antiparisnkomism and for extrapyramindal disorder control
  • Increase fluid intake for constipation, sips of water for dry mouth, keep fluids readily available, ice chips

Other types of AntiCholingenic meds:

  • Atropine reduction of secretions, vagal induced, bradycardia, ureteral and biliary colic
  • Dicyclomine Irritable bowel syndrome
  • Trimethobenzamide: Used for motion sickess, anti anesthesia Parkinson’s is caused by a deficiency in dopamine and excess of acetylcholine w that has No cure. Drigs are only use to manage, that will be changed For used in treatments is adjunts levodopa/carbidoca, which will have blood to the barrier May have have different used include : Mirpex: Requip for the Dopamine recotors Agonist Always asses the patients.

Nursing Alert :

observe patient if the have carbidopa

  • Keep them out of of water, give them the water yourself in small bites
  • The side effect of drug can cause GI Disturbance small and food with be prefered The use of small meals is to prevent difficulty in eating : dizzy.

Aterante for for treatment using parkincon's drugs, it can be for long time depending of drug holiday

Dopaminic Drugs can effect low dose: if you have them for high or serve

  • Use drugs (5 to 18 times)
  • Nursing Education*
  • Take a small part of these drug do not get of it
  • Avoid vitamin B6 If have 6, for diabetic,may interfere check

Anti partkisin drug are broken into two.

  • Anti visual : Amantade for synmple
  • *Complications, to the blood Hypertensive crisis with foods containing tyramine and merperidine, fluoxetine, MAOI, antidepressants, which you must watch out. You have to know parkinson in the drugs, be able to tell the drugs apart
  • The dopamine, you must use promipole
  • The one that make , mesyiolale

Cholinesterase Drugs

  • For pt with Alzeiermers, for short time due too memin

Cholinerghic drugs for anti cholinester

Help for those with MG, this will promote the most contraction. Use for urninary reten

  • Precautions:* Hypertension Epilepsy , it may promote the contracture. With other To help to keep the drug

Adverse Effect includes Topical skin and Flushing May cause and may have cardiac issues

  • Check it out in more detail:

  • For patients, that’s if you keep you out of water.

  • For fluid and what must you do in time

    Antispasmodic Medications

  • Anti-muscarinic medications are a type of Anticholinergics

  • Tolterodine for overachieve bladder

IV Therapy, Nursing Intervention

Wash Hands

  • Follow step for all patient before administering IV meds
  • Follow the site for hour. and tubing. 24 hour
  • Monitor for complications and fluid with
  • Always ensure to provide electrolyte imbalance with
  • Diuretic will to the work before.

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