Thyroid Drugs: Name, Class, Mechanism of Action, Uses, and Adverse Effects

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What is the standard of care for long-term treatment of hypothyroidism?

Taking the medication in the morning on an empty stomach

Which adverse effect is more likely to occur in elderly individuals or those with heart disease when taking thyroid drugs?

Cardiovascular events

What is a black box warning associated with antithyroid drugs like propylthiouracil (PTU)?

Severe liver injury or acute liver failure

Which condition warrants caution when using antithyroid drugs like propylthiouracil (PTU)?

Cardiovascular disease

What is a nursing implication for patients taking antithyroid drugs like propylthiouracil (PTU)?

Ensuring even distribution of doses around the clock

What should be monitored in patients taking antithyroid drugs like propylthiouracil (PTU) due to possible hematologic effects?

Complete blood count (CBC)

What is the primary reason for using alternate day therapy with corticosteroids?

To mimic endogenous secretion and decrease the risk of renal insufficiency

Which condition is NOT typically treated with corticosteroids according to the text?

Endocrine disorders like diabetes

What are some of the musculoskeletal effects associated with prolonged corticosteroid use?

Hypocalcemia leading to osteoporosis

Which of the following is a common integumentary effect of corticosteroid therapy?

Stretch marks

What CNS symptom might a patient experience due to corticosteroid therapy?

Insomnia

Which of the following is a cardiovascular symptom associated with corticosteroid use?

Hypotension

What is the main purpose of glucocorticoids?

Increase glucose in the blood

In which condition would a patient most likely need glucocorticoids?

Ulcerative colitis

Why is it important to schedule corticosteroids appropriately?

To avoid adrenal insufficiency

What is one of the adverse effects of glucocorticoids?

Weight gain

When might a patient need glucocorticoids for respiratory issues?

COPD exacerbation

What is the primary mechanism of action of glucocorticoids?

Decreasing inflammation

What is the function of stress doses in patients with adrenocortical insufficiency?

To compensate for the body's normal response to stress

Which adverse effect is associated with drugs used to treat Cushing's syndrome?

Hepatotoxicity

What is the mechanism of action of ketoconazole in treating Cushing's syndrome?

Prevents conversion of cortisol to 11-deoxycortisol

Why should PO doses of ketoconazole be taken with food?

To decrease gastric irritation

What should be taught to patients receiving drugs for adrenal gland disorders regarding their treatment?

Lifetime replacement may be necessary

Which endocrine effect is associated with stress doses in patients with adrenocortical insufficiency?

Hyperglycemia

Which drug acts to decrease capillary permeability and increase retention of sodium and water?

Fludrocortisone

What is the black box warning associated with drugs used to treat Addison's disease?

Should not receive live virus vaccines

What is the mechanism of action of desmopressin acetate (DDAVP) in treating neurogenic diabetes insipidus?

Decreases urine volume by increasing cAMP

Which drug is used to inhibit gonadotropin, thereby decreasing testosterone and estrogen?

Leuprolide acetate

What is the primary use of calcium preparations such as calcium carbonate (Tums)?

Relief from indigestion/heartburn

Which hormone is responsible for stimulating skeletal, muscle, and organ growth?

Somatropin

Which drug is used for acromegaly and works by inhibiting serotonin, GH, and insulin?

Octreotide

What is the main side effect associated with vitamin D supplementation?

Hypercalcemia

What is the primary use of somatropin in drug therapy?

Stimulate growth in children with growth deficiency.

What is the key role of calcitriol in bone metabolism and calcium regulation?

Increases serum calcium levels.

Test your knowledge on thyroid drugs including drug names, classes, mechanisms of action, uses, adverse effects, contraindications, and nursing implications. Explore the standard of care for long-term treatment of hypothyroidism, symptoms of hyperthyroidism, and important considerations for administration.

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