Thyroid Drugs: Name, Class, Mechanism of Action, Uses, and Adverse Effects
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Questions and Answers

What is the standard of care for long-term treatment of hypothyroidism?

  • Increasing the dose if symptoms worsen
  • Taking the medication in the evening before bed
  • Taking the medication in the morning on an empty stomach (correct)
  • Changing brands frequently to prevent tolerance

    • Which adverse effect is more likely to occur in elderly individuals or those with heart disease when taking thyroid drugs?

  • Gastrointestinal disturbances
  • Cardiovascular events (correct)
  • Respiratory complications
  • Central nervous system side effects

    • What is a black box warning associated with antithyroid drugs like propylthiouracil (PTU)?

  • Severe liver injury or acute liver failure (correct)
  • Severe kidney injury
  • Respiratory depression
  • Hypertensive crisis

    • Which condition warrants caution when using antithyroid drugs like propylthiouracil (PTU)?

    <p>Cardiovascular disease (A)</p> Signup and view all the answers

    What is a nursing implication for patients taking antithyroid drugs like propylthiouracil (PTU)?

    <p>Ensuring even distribution of doses around the clock (C)</p> Signup and view all the answers

    What should be monitored in patients taking antithyroid drugs like propylthiouracil (PTU) due to possible hematologic effects?

    <p>Complete blood count (CBC) (A)</p> Signup and view all the answers

    What is the primary reason for using alternate day therapy with corticosteroids?

    <p>To mimic endogenous secretion and decrease the risk of renal insufficiency (A)</p> Signup and view all the answers

    Which condition is NOT typically treated with corticosteroids according to the text?

    <p>Endocrine disorders like diabetes (D)</p> Signup and view all the answers

    What are some of the musculoskeletal effects associated with prolonged corticosteroid use?

    <p>Hypocalcemia leading to osteoporosis (D)</p> Signup and view all the answers

    Which of the following is a common integumentary effect of corticosteroid therapy?

    <p>Stretch marks (D)</p> Signup and view all the answers

    What CNS symptom might a patient experience due to corticosteroid therapy?

    <p>Insomnia (C)</p> Signup and view all the answers

    Which of the following is a cardiovascular symptom associated with corticosteroid use?

    <p>Hypotension (C)</p> Signup and view all the answers

    What is the main purpose of glucocorticoids?

    <p>Increase glucose in the blood (A)</p> Signup and view all the answers

    In which condition would a patient most likely need glucocorticoids?

    <p>Ulcerative colitis (A)</p> Signup and view all the answers

    Why is it important to schedule corticosteroids appropriately?

    <p>To avoid adrenal insufficiency (A)</p> Signup and view all the answers

    What is one of the adverse effects of glucocorticoids?

    <p>Weight gain (C)</p> Signup and view all the answers

    When might a patient need glucocorticoids for respiratory issues?

    <p>COPD exacerbation (A)</p> Signup and view all the answers

    What is the primary mechanism of action of glucocorticoids?

    <p>Decreasing inflammation (D)</p> Signup and view all the answers

    What is the function of stress doses in patients with adrenocortical insufficiency?

    <p>To compensate for the body's normal response to stress (D)</p> Signup and view all the answers

    Which adverse effect is associated with drugs used to treat Cushing's syndrome?

    <p>Hepatotoxicity (C)</p> Signup and view all the answers

    What is the mechanism of action of ketoconazole in treating Cushing's syndrome?

    <p>Prevents conversion of cortisol to 11-deoxycortisol (B)</p> Signup and view all the answers

    Why should PO doses of ketoconazole be taken with food?

    <p>To decrease gastric irritation (D)</p> Signup and view all the answers

    What should be taught to patients receiving drugs for adrenal gland disorders regarding their treatment?

    <p>Lifetime replacement may be necessary (B)</p> Signup and view all the answers

    Which endocrine effect is associated with stress doses in patients with adrenocortical insufficiency?

    <p>Hyperglycemia (C)</p> Signup and view all the answers

    Which drug acts to decrease capillary permeability and increase retention of sodium and water?

    <p>Fludrocortisone (D)</p> Signup and view all the answers

    What is the black box warning associated with drugs used to treat Addison's disease?

    <p>Should not receive live virus vaccines (D)</p> Signup and view all the answers

    What is the mechanism of action of desmopressin acetate (DDAVP) in treating neurogenic diabetes insipidus?

    <p>Decreases urine volume by increasing cAMP (B)</p> Signup and view all the answers

    Which drug is used to inhibit gonadotropin, thereby decreasing testosterone and estrogen?

    <p>Leuprolide acetate (D)</p> Signup and view all the answers

    What is the primary use of calcium preparations such as calcium carbonate (Tums)?

    <p>Relief from indigestion/heartburn (A)</p> Signup and view all the answers

    Which hormone is responsible for stimulating skeletal, muscle, and organ growth?

    <p>Somatropin (D)</p> Signup and view all the answers

    Which drug is used for acromegaly and works by inhibiting serotonin, GH, and insulin?

    <p>Octreotide (A)</p> Signup and view all the answers

    What is the main side effect associated with vitamin D supplementation?

    <p>Hypercalcemia (B)</p> Signup and view all the answers

    What is the primary use of somatropin in drug therapy?

    <p>Stimulate growth in children with growth deficiency. (C)</p> Signup and view all the answers

    What is the key role of calcitriol in bone metabolism and calcium regulation?

    <p>Increases serum calcium levels. (B)</p> Signup and view all the answers

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