Drugs acting on Skeletal Muscle Systems Quiz

The lecture is about drugs acting on the Cardiovascular System.

One of the objectives of the lecture is to discuss the pharmacology of drugs used to induce skeletal muscle paralysis.

The email provided for Professor M.Gossell-Williams is [email protected].

The arrival of an action potential at a nerve results in the release of the neurotransmitter called Serotonin.

The neurotransmitter travels in the cleft causing the development of Endplate Potential through the stimulation of Potassium channels.

The depolarization gets propagated down the muscle via Sodium channels.

Baclofen acts only on post-synaptic receptors to reduce motor neuron activation.

Diazepam primarily acts on GABA-B receptors in the spinal cord to decrease motor neuron activation.

The half-life of Baclofen is approximately 9 hours.

Dantrolene is not associated with hepatotoxicity and does not require monitoring.

Pyridostigmine inhibits the activity of acetylcholinesterase.

Muscle cramps and weakness are not listed as side effects of pyridostigmine.

The enzyme that terminates the action of the neurotransmitter is called Pseudocholinesterases.

Pancuronium has an ultrashort duration of action.

Dantrolene inhibits the release of Ca2+ from the sarcoplasmic reticulum.

Mivacurium and Pancuronium are metabolized by renal excretion.

Succinylcholine can cause malignant hyperthermia.

Mivacurium competitively blocks nicotinic receptors to inhibit the actions of acetylcholine.

Arrival of an action potential at a nerve results in the release of the neurotransmitter called Serotonin.

Mivacurium competitively blocks nicotinic receptors to inhibit the actions of acetylcholine.

Pancuronium has an ultrashort duration of action.

Succinylcholine can cause malignant hyperthermia.

Muscle cramps and weakness are not listed as side effects of pyridostigmine.

Baclofen acts only on post-synaptic receptors to reduce motor neuron activation.

Baclofen acts on pre-synaptic and post-synaptic receptors to reduce motor neuron activation.

Diazepam primarily potentiates GABA-B receptors in the spinal cord to decrease motor neuron activation.

Dantrolene is not associated with hepatotoxicity and does not require monitoring.

Pyridostigmine inhibits the activity of acetylcholinesterase.

Mivacurium competitively blocks nicotinic receptors to inhibit the actions of acetylcholine.

Succinylcholine can cause malignant hyperthermia.

Mivacurium and Pancuronium have similar pharmacokinetic properties due to their charged N groups.

Succinylcholine and Pancuronium have the same duration of action.

The drug Dantrolene is associated with hepatotoxicity and requires monitoring.

Pyridostigmine primarily acts on post-synaptic receptors to reduce motor neuron activation.

The enzyme that terminates the action of the neurotransmitter is called Serotonin.

Malignant hyperthermia is a side effect associated with Pancuronium.