31 Questions
Which term refers to the period following a seizure that usually presents with altered consciousness?
Postictal period
What is the term for continuous seizure lasting 5 minutes or more OR having 2 or more seizures without full recovery?
Status epilepticus
When is the keto diet typically indicated for managing seizures?
For refractory seizures after trying and failing ≥ 2 ASMs
What is a negative effect of the keto diet?
Hypercholesterolemia
Who commonly uses the keto diet?
Children and adolescents
What is considered 1st line in the initial treatment phase for seizures?
IV lorazepam
What occurs in the stabilization phase of status epilepticus?
Checking labs
Which drug should be avoided when a patient has absence seizures?
Carbamazepine (Tegretol)
What are the black box warnings with carbamazepine (Tegretol)?
Agranulocytosis
Which medication is a prodrug with the same major active metabolite as oxcarbazepine?
Eslicarbazepine acetate
(T/F) Hyponatremia is more common in oxcarbazepine (Trileptal) than carbamazepine (Tegretol).
(T)
What is a specific warning associated with ethosuximide?
Lupus
Which adverse effect is specifically linked to vigabatrin use?
Peripheral neuropathy
What monitoring is specifically recommended for felbamate use?
CBC w/diff
Which schedule classification does perampanel fall under?
CV
In which specific condition is cannabidiol (Epidiolex) indicated?
Seizures associated with Lennox-Gastaut syndrome
What is a common adverse effect associated with tiagabine use?
Mild cognitive impairment
Which seizure type is ethosuximide specifically used for?
Atypical absence seizures
What is the black box warning associated with vigabatrin use?
$ ext{BBW}$ for vision loss requiring a REMS program
'CV' schedule classification represents medications that have:
$ ext{High}$ potential for abuse
Which medication has a specific contraindication in familial short QT syndrome?
Rufinamide
What is the black box warning associated with valproate (Depakote)?
Hepatic failure, pancreatitis, teratogenicity
Which medication should be avoided in patients with a history of sinus bradycardia and certain heart blocks?
Phenytoin (Dilantin)
Which antiepileptic medication has the lowest incidence of hyponatremia?
Eslicarbazepine acetate
What can phenytoin (Dilantin) and fosphenytoin cause with chronic use?
Decreased bone mineral density
What are the warnings/precautions associated with levetiracetam (Keppra) and brivaracetam?
Risk of misuse
Which antiepileptic medication is contraindicated in mitochondrial disorders?
Valproate (Depakote)
When does SJS and TEN usually develop with lamotrigine (Lamictal)?
Within 2-8 weeks
What is the schedule of pregabalin (Lyrica)?
CV
What are the monitoring recommendations for valproate (Depakote)?
Therapeutic range = 50-125 mcg/mL, CBC w/diff, LFTs
Which antiepileptic medication has the highest risk of serious skin rashes, including SJS and TEN?
Lamotrigine (Lamictal)
Test your knowledge on drug interactions and adverse effects of antiepileptic drugs like eslicarbazepine acetate and lamotrigine (Lamictal). Learn about potential interactions with oral contraceptives and the black box warning associated with lamotrigine. Find out when serious skin rashes like SJS and TEN typically develop with lamotrigine.
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