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Questions and Answers
Which of the following best describes the action of a negative chronotropic drug?
Which of the following best describes the action of a negative chronotropic drug?
Which of the following conditions is a positive inotropic drug primarily used to treat?
Which of the following conditions is a positive inotropic drug primarily used to treat?
What is the primary effect of epinephrine on cardiac function?
What is the primary effect of epinephrine on cardiac function?
Dopamine is used to treat which of the following conditions, based on its cardiac effects?
Dopamine is used to treat which of the following conditions, based on its cardiac effects?
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Which of the following best describes the therapeutic action of dobutamine?
Which of the following best describes the therapeutic action of dobutamine?
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Which of the following best describes the dual action of Digoxin?
Which of the following best describes the dual action of Digoxin?
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Which of the following best describes the primary purpose of administering a drug?
Which of the following best describes the primary purpose of administering a drug?
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Pimobendan is primarily used to treat congestive heart failure (CHF) through which mechanism?
Pimobendan is primarily used to treat congestive heart failure (CHF) through which mechanism?
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Procainamide is used to treat VPC by which mechanism?
Procainamide is used to treat VPC by which mechanism?
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What distinguishes an over-the-counter (OTC) drug from a prescription drug?
What distinguishes an over-the-counter (OTC) drug from a prescription drug?
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What is the determining factor for 'extra-label drug use'?
What is the determining factor for 'extra-label drug use'?
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Propranolol and Atenolol are similar in that they both:
Propranolol and Atenolol are similar in that they both:
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What is the main goal of drug compounding?
What is the main goal of drug compounding?
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What distinguishes Class III antiarrhythmic drugs from other classes?
What distinguishes Class III antiarrhythmic drugs from other classes?
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Which aspect of a prescription label indicates how long a medication should be administered?
Which aspect of a prescription label indicates how long a medication should be administered?
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What does the 'therapeutic range' of a drug refer to?
What does the 'therapeutic range' of a drug refer to?
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What is the primary purpose of administering a loading dose of a drug?
What is the primary purpose of administering a loading dose of a drug?
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What does it indicate if a drug has a low margin of safety?
What does it indicate if a drug has a low margin of safety?
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What effect does protein binding typically have on drug distribution within the body?
What effect does protein binding typically have on drug distribution within the body?
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Pancuronium is a neuromuscular blocker that interferes with the action of which neurotransmitter?
Pancuronium is a neuromuscular blocker that interferes with the action of which neurotransmitter?
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Which drug is described as an anticonvulsant that requires monitoring due to its low therapeutic index?
Which drug is described as an anticonvulsant that requires monitoring due to its low therapeutic index?
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What is the primary use of phenobarbital in veterinary medicine?
What is the primary use of phenobarbital in veterinary medicine?
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Which drug should be avoided in patients with hypertension due to its effects on blood pressure?
Which drug should be avoided in patients with hypertension due to its effects on blood pressure?
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What is the function of goblet cells and cilia in the respiratory tract?
What is the function of goblet cells and cilia in the respiratory tract?
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What class of drugs is used to suppress a non-productive cough?
What class of drugs is used to suppress a non-productive cough?
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What is the role of mucolytics in respiratory treatment?
What is the role of mucolytics in respiratory treatment?
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Which medication is noted for its use in treating acetaminophen toxicity in cats and dogs?
Which medication is noted for its use in treating acetaminophen toxicity in cats and dogs?
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What do terbutaline and albuterol have in common?
What do terbutaline and albuterol have in common?
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What is the mechanism of action for methylxanthine bronchodilators?
What is the mechanism of action for methylxanthine bronchodilators?
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What is the application of Guaifenesin in veterinary medicine?
What is the application of Guaifenesin in veterinary medicine?
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What is the primary use of Diltiazem?
What is the primary use of Diltiazem?
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What is the function of ACE Inhibitors?
What is the function of ACE Inhibitors?
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What distinguishes sympathomimetics?
What distinguishes sympathomimetics?
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What is the primary role of Amlodipine?
What is the primary role of Amlodipine?
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What is the mechanism by which Acetylsalicylic Acid prevents clot formation?
What is the mechanism by which Acetylsalicylic Acid prevents clot formation?
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What do hemostatic drugs achieve?
What do hemostatic drugs achieve?
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What do arteriolar dilators primarily do?
What do arteriolar dilators primarily do?
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What is the effect of parasympatholytic drugs?
What is the effect of parasympatholytic drugs?
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What is the purpose of EDTA in medical treatments?
What is the purpose of EDTA in medical treatments?
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What is the primary neurotransmitter associated with the parasympathetic nervous system?
What is the primary neurotransmitter associated with the parasympathetic nervous system?
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Flashcards
Drug
Drug
A substance administered to diagnose, treat, or prevent disease, relieve pain, or improve physiological function.
Over-the-Counter (OTC) Drug
Over-the-Counter (OTC) Drug
A drug that can be purchased without a prescription.
Extra-Label Drug Use
Extra-Label Drug Use
When a veterinarian prescribes a drug for a use not specifically listed on its label.
Drug Compounding
Drug Compounding
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Duration of Treatment
Duration of Treatment
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Therapeutic Range
Therapeutic Range
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Loading Dose
Loading Dose
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Low Margin of Safety
Low Margin of Safety
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High Margin of Safety
High Margin of Safety
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Protein Binding
Protein Binding
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Diltiazem vs Verapamil
Diltiazem vs Verapamil
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Amlodipine
Amlodipine
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Vasodilator
Vasodilator
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ACE Inhibitors
ACE Inhibitors
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Acetylsalicylic Acid
Acetylsalicylic Acid
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EDTA
EDTA
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Heparin
Heparin
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Hemostatic Drugs
Hemostatic Drugs
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Blood Enhancing Drugs
Blood Enhancing Drugs
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Sympathetic Nervous System
Sympathetic Nervous System
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Negative chronotropic drugs
Negative chronotropic drugs
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Positive inotropic drugs
Positive inotropic drugs
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Negative inotropic drugs
Negative inotropic drugs
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Epinephrine
Epinephrine
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Dopamine
Dopamine
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Dobutamine
Dobutamine
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Digoxin
Digoxin
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Procainamide
Procainamide
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Propranolol
Propranolol
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Sotalol
Sotalol
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Diazepam
Diazepam
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Potassium bromide
Potassium bromide
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Acepromazine
Acepromazine
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Xylazine
Xylazine
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Dexmedetomidine
Dexmedetomidine
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Guaifenesin
Guaifenesin
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Mucolytics
Mucolytics
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Expectorants
Expectorants
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Terbutaline
Terbutaline
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Anticholinergics
Anticholinergics
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Study Notes
Drug Definitions and Classifications
- A drug is a substance administered to diagnose, treat, or prevent disease; relieve pain; or improve physiological function.
- An over-the-counter (OTC) drug can be purchased without a prescription.
- Extra-label drug use occurs when a veterinarian prescribes a drug for a use not explicitly listed on its label.
- Drug compounding combines or alters drugs to create a customized medication for a specific patient.
- Duration of treatment refers to the timeframe for administration, which is often included on a prescription label with details like dosage, route, and frequency.
- The therapeutic range is the drug concentration in the body that produces a desired effect with minimal toxicity.
- A loading dose is a higher initial amount of a drug given to quickly reach the therapeutic range.
Drug Properties
- Low margin of safety means a drug's effective dose is close to its lethal dose.
- High margin of safety occurs when the lethal dose is greater than the effective dose.
- Protein binding is the process of drug molecules binding to blood proteins (like albumin) which may slow their distribution.
- Ion trapping is when a drug becomes trapped in a body compartment due to differences in pH.
Cardiovascular Drugs
- Acetylcholine is a neurotransmitter released at the neuromuscular junction to stimulate muscle contraction.
- Pancuronium is a neuromuscular blocker that competes with acetylcholine for receptor sites and requires a reversal agent for muscle function restoration.
- Positive dromotropic drugs increase conduction of myocardial electrical impulses, used to treat heart block.
- Negative dromotropic drugs decrease conduction of myocardial electrical impulses, used to treat atrioventricular (AV) block.
- Positive chronotropic drugs increase heart rate, used to treat bradycardia.
- Negative chronotropic drugs decrease heart rate, used to treat tachycardia.
- Positive inotropic drugs increase the force of myocardial contraction, used to treat congestive heart failure.
- Negative inotropic drugs decrease the force of myocardial contraction, used to treat hypertension.
- Dopamine is a cardiac stimulant used to increase blood pressure, heart rate, and contraction.
- Dobutamine is a cardiac stimulant used to increase heart contraction and treat cardiac depression with hypotension.
- Digoxin and Digitoxin increase the strength of contraction and decrease heart rate, used to treat congestive heart failure (CHF).
- Pimobendane is a vasodilator used to treat CHF.
- Procainamide and Quinidine increase conduction time, used to treat ventricular premature complexes (VPCs) and ventricular arrhythmias.
- Tocainide and Lidocaine increase conduction time, used to treat ventricular tachycardia.
- Propranolol is a beta-blocker used to decrease automaticity (slow depolarization phase), treating ventricular arrhythmias.
- Atenolol is a beta-blocker used to decrease automaticity, treating hypertension.
- Sotolol, Amiodarone, and Bretylium are potassium channel blockers used to treat ventricular arrhythmias and reduce sinus rate.
- Diltiazem and Verapamil reduce spontaneous depolarization, treating ventricular tachycardia.
- Amlodipine treats hypertension and inhibits calcium movement, acting as a vasodilator.
Miscellaneous Drugs
- ACE inhibitors inhibit angiotensin-converting enzyme, leading to vasodilation and reduced cardiac afterload.
- Acetylsalicylic acid (aspirin) prevents clot formation by inhibiting thromboxane, affecting platelet stickiness.
- EDTA chelates calcium ions, preventing clot formation and used for blood tests or to chelate lead poison.
- Heparin stops the conversion of prothrombin to thrombin, used in blood tests or transfusions.
- Hemostatic drugs promote clotting to stop bleeding (e.g., silver nitrate, vitamin K, protamine sulfate).
- Blood-enhancing drugs (e.g., iron, erythropoietin) increase red blood cell production in the kidneys.
- Potassium bromide is an anticonvulsant used in dogs, with closely monitored blood levels due to its low therapeutic index.
- Acepromazine is used for sedation and as an anti-emetic.
- Xylazine treats pain and is used for sedation.
- Doxapram treats respiratory depression or arrest.
- Dexmedetomidine provides sedation and analgesia.
Nervous System Drugs
- Sympathetic nervous system is responsible for "fight or flight".
- Parasympathetic nervous system is responsible for energy-saving functions with acetylcholine as the primary neurotransmitter.
- Sympathomimetics mimic the sympathetic nervous system's effects.
- Sympatholytics inhibit the sympathetic nervous system.
- Parasympathomimetics mimic the parasympathetic nervous system's effects.
- Parasympatholytics inhibit the parasympathetic nervous system.
- Diazepam is a GABA inhibitory neurotransmitter.
- Pentobarbital is a barbiturate used in euthanasia.
Respiratory Drugs
- Goblet cells and cilia help remove foreign material in the respiratory tract.
- Antitussives suppress non-productive coughs.
- Anticholinergics block acetylcholine receptors and prevent bronchoconstriction.
- Acetylcysteine is a mucolytic drug used to treat acetaminophen toxicity in animals.
- Guaifenesin increases liquid secretion.
- Phenylephrine is a decongestant used to decrease nasal passage blockage.
- Methylxanthine bronchodilators inhibit enzymes that promote bronchoconstriction.
- Terbutaline and albuterol are beta2-adrenergic agonist drugs used to treat feline asthma.
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Description
This quiz explores various definitions and classifications related to drugs, including OTC drugs, extra-label use, and compounding. Additionally, it covers important drug properties such as therapeutic range and margin of safety. Test your knowledge on the essential concepts of pharmacology.