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Questions and Answers
What is the best route of administering a drug with extensive first pass effect for emergency use?
Intravenous (IV) administration is the best route.
Why is intravenous administration preferred in emergencies for drugs with high first pass metabolism?
It provides immediate delivery into the bloodstream and avoids metabolic degradation.
What challenges does extensive first pass metabolism present for emergency drug administration?
It reduces the bioavailability of the drug, making it less effective.
How does the route of administration affect the pharmacokinetics of a drug in emergency situations?
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In what scenarios might another route of drug administration, aside from IV, be considered despite first pass effects?
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