Drug Absorption and Elimination Flashcards
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Questions and Answers

What factors can affect how drugs enter the bloodstream?

  • Type of drug
  • Rate of entry
  • Concentration of the drug
  • All of the above (correct)

How does the way a drug enters the body affect its absorption?

It impacts the rate it enters the bloodstream and the extent of the effect of the substance.

Alcohol requires digestion before it enters the bloodstream.

False (B)

What is used to measure the amount of alcohol in the system?

<p>Concentration</p> Signup and view all the answers

Where is most alcohol absorbed?

<p>Small intestine</p> Signup and view all the answers

Why is alcohol absorbed faster than food?

<p>Alcohol does not have to be digested.</p> Signup and view all the answers

List some factors that determine the rate of alcohol absorption.

<p>Alcohol strength, food, carbonation, other beverage ingredients, emotions, gender.</p> Signup and view all the answers

Higher alcohol concentration will lead to slower absorption.

<p>False (B)</p> Signup and view all the answers

What effect does food have on alcohol absorption?

<p>It slows down absorption.</p> Signup and view all the answers

Estimates for absorption are - on an empty stomach versus - on a full stomach.

<p>20-40 minutes, 60-90 minutes</p> Signup and view all the answers

What accelerates the absorption of alcohol into the bloodstream?

<p>Carbonation</p> Signup and view all the answers

Strong emotions can slow down alcohol absorption.

<p>False (B)</p> Signup and view all the answers

What enzyme do women have less of that affects alcohol metabolism?

<p>Alcohol dehydrogenase</p> Signup and view all the answers

Because females have less of this enzyme, up to _____ more alcohol may be absorbed into their bloodstream.

<p>30%</p> Signup and view all the answers

The faster alcohol is consumed, the slower its effects will occur.

<p>False (B)</p> Signup and view all the answers

How does the size of a drink affect its impact?

<p>The larger the drink, the more effect it will have.</p> Signup and view all the answers

At what rate do average individuals eliminate alcohol from their bodies?

<p>.015 BAL per hour</p> Signup and view all the answers

Blood alcohol level will continue to rise even if a person stops drinking.

<p>True (A)</p> Signup and view all the answers

Why do people feel more sober after their blood alcohol level has peaked?

<p>They compare their current state to the worst level of impairment.</p> Signup and view all the answers

How does the method of putting a drug into the system affect its absorption?

<p>It varies how quickly the drug reaches the bloodstream.</p> Signup and view all the answers

Injection allows a drug to enter the bloodstream instantly.

<p>True (A)</p> Signup and view all the answers

What does the rate of absorption depend on when swallowing a drug?

<p>Type of drug and amount of food in the stomach.</p> Signup and view all the answers

What happens to substances when they are smoked?

<p>They are transferred very quickly to the brain.</p> Signup and view all the answers

Smoking is a slower method of transferring substances to the brain than injection.

<p>False (B)</p> Signup and view all the answers

Inhaling a substance is similar to which other method?

<p>Smoking</p> Signup and view all the answers

A higher percentage of active ingredient in a drug usually leads to slower absorption.

<p>False (B)</p> Signup and view all the answers

How are most drugs eliminated from the body?

<p>By being metabolized or excreted.</p> Signup and view all the answers

What are some key factors to remember about alcohol absorption?

<p>70%-80% of alcohol is absorbed through the small intestine, food slows down absorption, and strong emotions speed up absorption.</p> Signup and view all the answers

Flashcards

Drug Absorption

The process of a drug entering the bloodstream.

Alcohol Absorption

Alcohol's entry into the bloodstream, faster than food.

Blood Alcohol Level (BAL)

The concentration of alcohol in the blood, measured, not total content.

Small Intestine Absorption

70-80% of alcohol absorbed here.

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Factors Influencing Absorption

Things that impact how quickly a drug is absorbed, like food, emotions, concentration etc.

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Food and Absorption

Food slows down alcohol absorption.

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High Alcohol Concentration

Absorbs quickly, but excess 100-proof alcohol absorbs slower.

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Carbonation and Absorption

Carbonation accelerates alcohol absorption.

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Empty Stomach Absorption

Alcohol absorption in empty stomach is 20-40 min.

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Full Stomach Absorption

Alcohol absorption in a full stomach is 60-90 mins.

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Emotional Effects on Absorption

Strong emotions speed up alcohol absorption.

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Gender and Absorption

Women absorb up to 30% more alcohol than men due to lower alcohol dehydrogenase.

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Consumption Rate and Effects

Faster consumption leads to quicker and larger effects.

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Alcohol Elimination Rate

About 0.015 BAL per hour.

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Temporary BAL Rise

BAL can rise temporarily even after stopping drinking.

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Perception of Sobriety

Individuals may misjudge their sobriety after drinking.

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Intravenous Injection

Direct entry of drug into the bloodstream.

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Swallowing Absorption

Absorption depends on drug type and food.

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Smoking Absorption

Rapid transfer to the brain.

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Inhaling Absorption

Similar to smoking, quick absorption.

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Drug Elimination

Drugs are broken down or removed from the body via kidneys, saliva, sweat etc.

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Drug Metabolism and Excretion

Drug are broken down or excreted by kidneys, saliva and sweat etc.

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Variable Elimination Rates

Elimination rates differ based on drug type and health.

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Study Notes

Drug Absorption

  • Drug absorption effects vary by drug type, entry rate into the bloodstream, concentration, and other influencing factors.
  • How a drug enters the body affects its absorption rate and overall effect.
  • Alcohol does not require digestion, leading to faster absorption compared to food.

Alcohol Absorption

  • Blood alcohol level (BAL) is measured by concentration rather than total content in the system.
  • Approximately 70%-80% of alcohol is absorbed in the small intestine.
  • Faster absorption of alcohol occurs since it does not need digestion, unlike food.

Factors Influencing Absorption Rate

  • Key factors include alcohol strength, food presence, carbonation, other beverage ingredients, emotions, and gender.
  • High alcohol-concentration beverages are absorbed quickly; however, excess 100-proof alcohol absorbs more slowly due to stomach irritation.
  • Food slows absorption by coating the stomach and diluting alcohol rather than soaking it up.

Time Estimates

  • Absorption estimates: 20-40 minutes on an empty stomach, 60-90 minutes on a full stomach.
  • Carbonation accelerates alcohol absorption.

Emotional Effects

  • Strong emotions like anger or stress can quicken the absorption of alcohol from the stomach.

Gender Differences

  • Women have less alcohol dehydrogenase, the enzyme responsible for breaking down alcohol, leading to up to 30% more alcohol absorbed in their bloodstream compared to men.

Consumption Rate

  • Faster alcohol consumption correlates with quicker and greater effects; larger drinks enhance effects.

Alcohol Elimination

  • Average alcohol elimination rate is approximately 0.015 BAL per hour.
  • Despite ceasing drinking, BAL may continue to rise temporarily.

Perception of Sobriety

  • After drinking, individuals may perceive themselves as more sober than they actually are, influenced by previous impairment levels.

Drug Administration Methods

  • Injection: Intravenous injection provides instant entry into the bloodstream.
  • Swallowing: Absorption rate depends on drug type and food in the stomach.
  • Smoking: Transfers substances to the brain rapidly, faster than injection or swallowing.
  • Inhaling: Similar to smoking, resulting in quick absorption and action.
  • Higher active ingredient percentage in a drug generally leads to faster bloodstream delivery.

Drug Elimination

  • Drugs are metabolized or excreted; majority eliminated via kidneys in urine, some through saliva, sweat, or exhalation.
  • Elimination rates vary significantly based on drug type and individual health conditions.

Summary of Alcohol Absorption

  • Key points to remember: 70%-80% of alcohol absorbed in the small intestine; food slows absorption; strong emotions increase absorption rate; gender affects absorption efficiency.

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Description

Explore key concepts related to drug absorption and elimination with these flashcards. Each card focuses on essential terms and definitions that explain how drugs enter the body and their effects on the bloodstream. Ideal for students in pharmacology or related fields.

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