Docusate Sodium (Colace) Flashcards

What is the trade name for docusate sodium?

What is the therapeutic class of docusate sodium?

What is the primary route of administration for docusate sodium?

What is the mechanism of action for docusate sodium?

Which of the following is NOT an indication for docusate sodium?

Which of the following are common side effects of docusate sodium? (Select all that apply)

Which condition is a contraindication for using docusate sodium?

What should be assessed before administering docusate sodium?

What should be assessed after administering docusate sodium?

Adequate _____ consumption is as necessary as bulk for patients taking docusate sodium.

Normal bowel movements occur daily.

What should patients be advised regarding the presence of abdominal pain?

Docusate Sodium (Colace) Overview

Trade names include Colace and Doculace.
Classified as a laxative and emollient.
Minimal absorption, not metabolized, and excreted via bile.
Half-life remains unknown.

Pharmacokinetics

Oral onset: approximately 24 hours.
Rectal onset: around 4-6 hours.

Dosage and Administration

Adult dosage ranges from 50-300 mg per day.
Can use 240 mg as a PRN enema (4 mL).
Administered orally or rectally.

Mechanism of Action

Enhances water and fat penetration in the intestine.
Facilitates easier stool passage, preventing constipation.

Indications

Prevents hard, dry stool formation.
Aids in the prevention of constipation.
Softens fecal impaction, making bowel movements easier.

Side Effects

Common side effects include:
- Bitter taste and throat irritation.
- Nausea and vomiting.
- Anorexia and abdominal cramps.
- Diarrhea and possible rash.

Contraindications

Not suitable for individuals with:
- Known hypersensitivity to the drug.
- Intestinal obstruction or fecal impaction.
- Presence of nausea or vomiting.

Checks Before Administration

Conduct a baseline assessment including:
- Vital signs (BP, HR, RR, ECG).
- Mental status and lung sounds.
- Screening for allergies.
Observe for signs of edema.

Checks After Administration

Reassess vital signs and monitor for changes in mental status and ECG.
Look for symptoms and signs of cramps, rectal bleeding, nausea, or vomiting.

Patient Education

Emphasize the importance of adequate fluid consumption alongside bulk intake.
Clarify that normal bowel movements do not necessarily occur daily.
Advise against use if abdominal pain or nausea is present.

Test your knowledge of Docusate Sodium, also known as Colace, with these flashcards. Explore its trade names, therapeutic class, pharmacokinetics, pharmacodynamics, dosage, and administration routes. Perfect for pharmacy students or anyone interested in medical knowledge.