Podcast
Questions and Answers
What is the function of RNA primase in DNA replication?
What is the function of RNA primase in DNA replication?
- Helps DNA polymerase stay attached to the template strand
- Removes RNA primers from the new strands of DNA
- Repairs the gaps left after RNase H degrades RNA nucleotides
- Synthesizes short RNA primers to provide a 3’ end for DNA polymerase (correct)
What is the role of the sliding clamp in DNA replication?
What is the role of the sliding clamp in DNA replication?
- Binds to DNA polymerase and helps it stay attached to the template strand (correct)
- Removes RNA primers from the new DNA strands
- Repairs the gaps left after RNase H degrades RNA nucleotides
- Synthesizes short RNA primers for DNA polymerase
Why are Okazaki fragments formed during DNA replication?
Why are Okazaki fragments formed during DNA replication?
- To facilitate the binding of DNA polymerase to the template strand
- Due to the antiparallel orientation of the lagging strand (correct)
- To provide a 5’ end for DNA polymerase
- To repair damaged DNA nucleotides
What is the enzyme responsible for degrading the RNA nucleotides in the RNA primers?
What is the enzyme responsible for degrading the RNA nucleotides in the RNA primers?
Why does DNA polymerase require a pre-existing chain or primer to start the replication process?
Why does DNA polymerase require a pre-existing chain or primer to start the replication process?
What is the name of the repetitive sequences of DNA that protect the ends of eukaryotic chromosomes?
What is the name of the repetitive sequences of DNA that protect the ends of eukaryotic chromosomes?
Which enzyme can extend the ends of the chromosomes by adding more telomeric repeats to the 3’ end of the lagging strand?
Which enzyme can extend the ends of the chromosomes by adding more telomeric repeats to the 3’ end of the lagging strand?
What is the first safeguard against mutations during DNA replication?
What is the first safeguard against mutations during DNA replication?
What happens to telomeres with each cell division in eukaryotic cells?
What happens to telomeres with each cell division in eukaryotic cells?
Which type of cells are vulnerable to cellular senescence or apoptosis due to telomere shortening?
Which type of cells are vulnerable to cellular senescence or apoptosis due to telomere shortening?
