DNA Repair Enzymes

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What happens to a cell that has stopped dividing due to cellular ageing?

Senescence

What is the result of failure to repair extensive DNA damage?

One of three states: Senescence, Apoptosis or Unregulated cell division

What is the role of photolyases in DNA repair?

To reversibly bind and convert lesions back to original bases in the presence of visible light

What is the outcome of unregulated cell division?

Formation of a malignant tumor

What is necessary for photoreactivation to occur?

Visible light

What is the process by which a cell identifies and repairs DNA damage?

DNA repair

What determines the rate of DNA repair?

Cell type, cell age, and extracellular environment

What is the result of apoptosis?

Cells destroy themselves

What is the only biomolecule that can be repaired?

DNA

What is the term for the process by which DNA damage is directly reversed?

Single-Strand Break Repair

What is the outcome of cellular senescence?

Cells stop dividing

Learn about the different types of DNA repair enzymes, including alkyltransferase and methyl guanine methyltransferase, and how they correct DNA damage. Understand the process of single-strand break repair and excision repair.

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