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Questions and Answers
Which major mammalian DNA repair pathway is responsible for repairing external damage, such as UV damage?
Which major mammalian DNA repair pathway is responsible for repairing external damage, such as UV damage?
- Nucleotide excision repair (correct)
- DNA strand break repair
- Mismatch excision repair
- Base excision repair
Which type of genetic disease is caused by recessively inherited defects in different NER genes?
Which type of genetic disease is caused by recessively inherited defects in different NER genes?
- Cystic fibrosis
- Xeroderma pigmentosum (correct)
- Sickle cell anemia
- Huntington's disease
Which type of repair pathway is responsible for repairing single strand breaks in DNA?
Which type of repair pathway is responsible for repairing single strand breaks in DNA?
- Single strand break repair (correct)
- Double strand break repair
- Nonhomologous end joining
- Homologous recombination
Which repair pathway is responsible for repairing double strand breaks in DNA through the use of homologous sequences?
Which repair pathway is responsible for repairing double strand breaks in DNA through the use of homologous sequences?
Which type of repair pathway is responsible for removing damaged sections of DNA and filling the gap with DNA polymerase?
Which type of repair pathway is responsible for removing damaged sections of DNA and filling the gap with DNA polymerase?
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Study Notes
DNA Repair Pathways
- Nucleotide Excision Repair (NER) is responsible for repairing external damage, such as UV damage.
- Recessively inherited defects in NER genes can cause Xeroderma Pigmentosum, a genetic disease.
- Base Excision Repair (BER) is responsible for repairing single strand breaks in DNA.
- Homologous Recombination (HR) repair pathway is responsible for repairing double strand breaks in DNA through the use of homologous sequences.
- Nucleotide Excision Repair (NER) is also responsible for removing damaged sections of DNA and filling the gap with DNA polymerase.
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