5 Questions
Which major mammalian DNA repair pathway is responsible for repairing external damage, such as UV damage?
Nucleotide excision repair
Which type of genetic disease is caused by recessively inherited defects in different NER genes?
Xeroderma pigmentosum
Which type of repair pathway is responsible for repairing single strand breaks in DNA?
Single strand break repair
Which repair pathway is responsible for repairing double strand breaks in DNA through the use of homologous sequences?
Homologous recombination
Which type of repair pathway is responsible for removing damaged sections of DNA and filling the gap with DNA polymerase?
Base excision repair
Study Notes
DNA Repair Pathways
- Nucleotide Excision Repair (NER) is responsible for repairing external damage, such as UV damage.
- Recessively inherited defects in NER genes can cause Xeroderma Pigmentosum, a genetic disease.
- Base Excision Repair (BER) is responsible for repairing single strand breaks in DNA.
- Homologous Recombination (HR) repair pathway is responsible for repairing double strand breaks in DNA through the use of homologous sequences.
- Nucleotide Excision Repair (NER) is also responsible for removing damaged sections of DNA and filling the gap with DNA polymerase.
Test your knowledge on DNA repair mechanisms with this quiz! Learn about the major mammalian DNA repair pathways, including nucleotide excision repair, mismatch excision repair, base excision repair, and DNA strand break repair. Explore the different types of strand break repair pathways, such as single strand break repair and double strand break repair through nonhomologous end joining and homologous recombination. Challenge yourself and gain a deeper understanding of the fascinating world of DNA repair.
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