Podcast
Questions and Answers
Which type of radiation is absorbed strongly by DNA and can cause damage?
Which type of radiation is absorbed strongly by DNA and can cause damage?
- X-rays
- Gamma rays
- UV-B rays
- UV-C rays (correct)
Which enzyme is responsible for repairing mismatched bases during DNA replication?
Which enzyme is responsible for repairing mismatched bases during DNA replication?
- Exonuclease
- Oxygen radicals
- Polymerase
- MMR enzyme (correct)
How many genes participating in DNA repair were revealed by the recent publication of the human genome?
How many genes participating in DNA repair were revealed by the recent publication of the human genome?
- Less than 130
- More than 130 (correct)
- 130
- The number is unknown
Which mechanism of DNA repair involves the removal and replacement of damaged bases?
Which mechanism of DNA repair involves the removal and replacement of damaged bases?
Which enzyme is responsible for removing a specific kind of base damage in the Base Excision Repair (BER) process?
Which enzyme is responsible for removing a specific kind of base damage in the Base Excision Repair (BER) process?
Which enzyme is responsible for synthesizing to fill in the gap in the Base Excision Repair (BER) process?
Which enzyme is responsible for synthesizing to fill in the gap in the Base Excision Repair (BER) process?
Which enzyme is responsible for removing Uracil in the Nucleotide Excision Repair (NER) process?
Which enzyme is responsible for removing Uracil in the Nucleotide Excision Repair (NER) process?
Which enzyme is responsible for filling in the correct nucleotides in the Nucleotide Excision Repair (NER) process?
Which enzyme is responsible for filling in the correct nucleotides in the Nucleotide Excision Repair (NER) process?
Which proteins are involved in recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases in the Mismatch Repair (MMR) process?
Which proteins are involved in recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases in the Mismatch Repair (MMR) process?
Which of the following is the main function of the proteasome?
Which of the following is the main function of the proteasome?
What is the significance of the 2004 Nobel Prize in Chemistry awarded to Aaron Ciechanover, Avram Hershko, and Irwin Rose?
What is the significance of the 2004 Nobel Prize in Chemistry awarded to Aaron Ciechanover, Avram Hershko, and Irwin Rose?
What is the most common source of genetic variation between humans?
What is the most common source of genetic variation between humans?
What are polymorphisms?
What are polymorphisms?
Which mechanism is used by the cell to repair a complete break in a DNA molecule?
Which mechanism is used by the cell to repair a complete break in a DNA molecule?
Which proteins are used in homologous recombination to repair double strand breaks?
Which proteins are used in homologous recombination to repair double strand breaks?
Which phase of the cell cycle does DNA replication occur?
Which phase of the cell cycle does DNA replication occur?
Which checkpoint in the cell cycle ensures that everything is ready to enter the M (mitosis) phase and divide?
Which checkpoint in the cell cycle ensures that everything is ready to enter the M (mitosis) phase and divide?
function of BER enzymes
function of BER enzymes
function of enzymes in NER
function of enzymes in NER
Function of enzymes in MMR
Function of enzymes in MMR
Defect in MMR genes are associated with?
Defect in MMR genes are associated with?
BER, NER, and MMR are all apart of what repairing system?
BER, NER, and MMR are all apart of what repairing system?
Direct joining can also be called
Direct joining can also be called
To fix a complete break in double strand breaks what two things can be done?
To fix a complete break in double strand breaks what two things can be done?
Cell cycle checkpoint protein
Cell cycle checkpoint protein
Twp apoptotic genes are?
Twp apoptotic genes are?
What is the role of Ubiquitin-proteasome?
What is the role of Ubiquitin-proteasome?
Genetic alterations that occur in more than___ percent of the population are called polymorphisms.
Genetic alterations that occur in more than___ percent of the population are called polymorphisms.
Match associated cancers with mutation
Match associated cancers with mutation
Components related to the particular trinucleotide repeat diseases.
Components related to the particular trinucleotide repeat diseases.
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