DNA Mismatch Repair Proteins

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Questions and Answers

Which protein is present only in E. coli and some other gram-negative bacteria?

  • MutS
  • MutH (correct)
  • MutL
  • MSH2

Which proteins are homologous to MutS and MutL in eukaryotes?

  • MSH2 and MSH6 (correct)
  • MLH1 and PMS2
  • MSH2 and MSH3
  • MSH3 and MSH6

What is the name of the heterodimer formed by MSH2 and MSH6 in humans?

  • MutSβ
  • MutHα
  • MutSα (correct)
  • MutLα

Which homologs of the bacterial MutL protein participate in mismatch repair in mammals?

<p>MLH1 and PMS2 (D)</p> Signup and view all the answers

Who reconstituted the human mismatch repair system in vitro?

<p>Paul Modrich (B)</p> Signup and view all the answers

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